Abstract:
:Early treatment, soon after infection, reduces HIV transmissions and benefits patients. The Transmission Reduction Intervention Project (TRIP) evaluated a network intervention to detect individuals recently infected (in the past 6 months). TRIP was conducted in Greece (2013-2015) and focused on drug injector networks. Based on HIV status, testing history, and the results of an assay to detect recent infections, TRIP classified drug injector "Seeds" into groups: Recent Seeds (RS), and Control Seeds with Long-term HIV infection (LCS). The network members of RS and LCS were traced for two steps. The analysis included 23 RS, 171 network members of the RS, 19 LCS, and 65 network members of the LCS. The per-seed number of recents detected in the network of RS was 5 times the number in the network of LCS (Ratio RS vs. LCS: 5.23; 95% Confidence Interval (CI): 1.54-27.61). The proportion of recents among HIV positives in the network of RS (27%) was approximately 3 times (Ratio RS vs. LCS: 3.30; 95% CI: 1.04-10.43) that in the network of LCS (8%). Strategic network tracing that starts with recently infected persons could support public health efforts to find and treat people early in their HIV infection.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Nikolopoulos GK,Pavlitina E,Muth SQ,Schneider J,Psichogiou M,Williams LD,Paraskevis D,Sypsa V,Magiorkinis G,Smyrnov P,Korobchuk A,Vasylyeva TI,Skaathun B,Malliori M,Kafetzopoulos E,Hatzakis A,Friedman SRdoi
10.1038/srep38100subject
Has Abstractpub_date
2016-12-05 00:00:00pages
38100issn
2045-2322pii
srep38100journal_volume
6pub_type
杂志文章abstract::This study aimed to identify single nucleotide polymorphisms (SNPs) associated with milk cholesterol (CHL) content via a genome wide association study (GWAS). Milk CHL content was determined by gas chromatography and expressed as mg of CHL in 100 g of fat (CHL_fat) or in 100 mg of milk (CHL_milk). GWAS was performed w...
journal_title:Scientific reports
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2014-07-16 00:00:00
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pub_type: 杂志文章
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更新日期:2016-09-22 00:00:00
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journal_title:Scientific reports
pub_type: 杂志文章
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更新日期:2016-04-21 00:00:00
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journal_title:Scientific reports
pub_type: 杂志文章
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更新日期:2017-07-14 00:00:00
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pub_type: 杂志文章
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更新日期:2017-07-12 00:00:00
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pub_type: 杂志文章
doi:10.1038/s41598-018-25714-z
更新日期:2018-05-08 00:00:00
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journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46082
更新日期:2017-04-19 00:00:00
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journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21964-z
更新日期:2018-02-26 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2017-08-24 00:00:00
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journal_title:Scientific reports
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更新日期:2015-09-29 00:00:00
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journal_title:Scientific reports
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更新日期:2015-11-26 00:00:00
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journal_title:Scientific reports
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