The role of autophagy in THP-1 macrophages resistance to HIV- vpr-induced apoptosis.

abstract：:The tumor-associated immune response is governed by the signalling events of various regulatory molecules, one of which is the cytotoxic T lymphocyte-associated antigen 4 (CTLA-4). In conventional T cells, CTLA-4 could outcompete CD28 in binding to CD80/86 but does not produce a co-stimulatory signal, resulting in T c...

journal_title：Experimental cell research

authors： Lang C,Wang J,Chen L

更新日期：2017-11-15 00:00:00

abstract：:Mps-one-binder (Mob) proteins play a crucial role in yeast cytokinesis. After cloning two Mob1-like genes, MsMob1-A and MsMob1-B from alfalfa (Medicago sativa L.) we show that, although they are constitutively expressed in roots, stems, leaves, flowers and pods, their transcripts and proteins are mostly produced in ac...

journal_title：Experimental cell research

authors： Citterio S,Piatti S,Albertini E,Aina R,Varotto S,Barcaccia G

更新日期：2006-04-15 00:00:00

abstract：:Protein kinase C (PKC) is a family of Ser/Thr protein kinases categorized into three subfamilies: classical, novel, and atypical. The subcellular localization of classical PKCalpha, -betaI, and -gamma in the process of porcine oocyte maturation, fertilization, and parthenogenetic activation and their involvement in co...

journal_title：Experimental cell research

authors： Fan HY,Tong C,Li MY,Lian L,Chen DY,Schatten H,Sun QY

更新日期：2002-07-15 00:00:00

abstract：:Insulin-like growth factor I (IGF-I) promotes the motility of different cell types. We investigated the role of IGF-I receptor (IGF-IR) signaling in locomotion of MCF-7 breast cancer epithelial cells overexpressing the wild-type IGF-IR (MCF-7/IGF-IR). Stimulation of MCF-7/IGF-IR cells with 50 ng/ml IGF-I induced disru...

journal_title：Experimental cell research

authors： Guvakova MA,Surmacz E

更新日期：1999-08-25 00:00:00

abstract：:The ultrastructural localization of adenylate cyclase was studied in bovine cumulus-oocyte complexes. Adenylate cyclase was observed on the plasma membrane of the oocyte and occasionally on the plasma membrane of cumulus cells. The cytochemical observations presented demonstrate that there is more adenylate cyclase in...

journal_title：Experimental cell research

authors： Kuyt JR,Kruip TA,de Jong-Brink M

更新日期：1988-01-01 00:00:00

abstract：:Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population and show significant expansion under pathological conditions. microRNA plays important roles in many biological processes, whether microRNAs have a function in the expansion of MDSCs is still not very clear. In this study, miR-34a overexpression c...

journal_title：Experimental cell research

authors： Huang A,Zhang H,Chen S,Xia F,Yang Y,Dong F,Sun D,Xiong S,Zhang J

更新日期：2014-08-15 00:00:00

abstract：:A highly sensitive, kinetically unambiguous assay for alpha-factor-induced delay of cell passage through the "start" step of cell division in yeast is presented. The assay employs perfusion with periodic microscopy to monitor the bud emergence kinetics on the 20% of cells within an exponentially growing population whi...

journal_title：Experimental cell research

authors： Moore SA

更新日期：1987-08-01 00:00:00

abstract：:A method for isolation of C-cells from rat fetuses was developed, and the morphological plasticity of the cells in primary culture systems was tested. Thyroid-parathyroid-ultimobranchial body (UB) complexes from 16-day rat fetuses were treated with 0.1% collagenase and 1000 PU/ml Dispase at 37 degrees C for 1 h. After...

journal_title：Experimental cell research

authors： Nishiyama I,Fujii T

更新日期：1992-02-01 00:00:00

abstract：:The mechanisms of replicative senescence by telomere shortening are not fully understood. The Indian muntjac has the fewest chromosomes of all mammals, greatly simplifying the analysis of each telomere over time. In this study, telomere shortening was observed throughout the life span of cultured normal muntjac cells ...

journal_title：Experimental cell research

authors： Zou Y,Yi X,Wright WE,Shay JW

更新日期：2002-11-15 00:00:00

abstract：:Cultured megakaryocytes, isolated from guinea pig bone marrow, were treated with buffer or adenosine diphosphate (ADP) (10 microM) on plain or coated glass surfaces. Control cells were rounded and non-adherent. The nucleotide induced the cells to spread to several times the initial diameter, and to become flattened an...

journal_title：Experimental cell research

authors： Leven RM,Nachmias VT

更新日期：1984-06-01 00:00:00

abstract：:Release of mitochondrial cytochrome c has been recently linked to the activation of the "executioner" phase of the cellular programs for death by apoptosis. This release is known to be negatively regulated by Bcl-2 and Bcl-XL proteins. We show here that treatment of human leukemia cells HL60 with 1,25-dihydroxyvitamin...

journal_title：Experimental cell research

authors： Wang X,Studzinski GP

更新日期：1997-08-25 00:00:00

abstract：:With multiple divisions in culture, normal diploid cells suffer a loss of growth potential that leads to replicative senescence and a finite replicative capacity. Using quantitative RT-PCR, we have monitored mRNA expression levels of c-fos, c-jun, JunB, c-myc, p53, H-ras, and histone H4 during the replicative senescen...

journal_title：Experimental cell research

authors： Irving J,Feng J,Wistrom C,Pikaart M,Villeponteau B

更新日期：1992-09-01 00:00:00

abstract：:The interphase nucleus is a structurally ordered, three-dimensional structure, in which specific chromatin domains occupy distinct spatial positions that can, in turn, be modified with changes in cell function. A fundamental goal in developmental neurobiology is the identification of mechanisms that dictate the orderl...

journal_title：Experimental cell research

authors： Martou G,De Boni U

更新日期：2000-04-10 00:00:00

abstract：:Macrophage polarization plays a crucial role in regulating myocardial inflammation and injuries of coxsackievirus B3 (CVB3)-induced viral myocarditis (VM). It has been reported that miR-223 is a potent regulator of inflammatory responses that involved in macrophage polarization. However, the functional roles of miR-22...

journal_title：Experimental cell research

authors： Gou W,Zhang Z,Yang C,Li Y

更新日期：2018-05-01 00:00:00

abstract：:When mesenchymal cells from the early chick limb bud (stage 23-24) are plated at high cell density they spontaneously undergo chondrogenesis implicating extensive cell-to-cell interactions. In the past it has been shown that TGF-beta and vitamin D can influence this process and can stimulate chondrogenesis. Given the ...

journal_title：Experimental cell research

authors： Tsonis PA,Del Rio-Tsonis K,Millan JL,Wheelock MJ

更新日期：1994-08-01 00:00:00

abstract：:The CDC25Mm gene codes for Ras-guanine nucleotide exchange factors. Four different full-length cDNA clones derived from the same gene and coding for proteins of different sizes that have in common the last 661 amino acids have been isolated from mouse brain. In order to investigate the expression of the products of th...

journal_title：Experimental cell research

authors： Ferrari C,Zippel R,Martegani E,Gnesutta N,Carrera V,Sturani E

更新日期：1994-02-01 00:00:00

abstract：:In mammalian cells, it has been shown that adjacent multiple DNA replicons, termed a replicon cluster or a replicon domain, are replicated coordinately in a defined temporal order during the DNA synthetic (S) phase. However, no intranuclear structure of this replicon domain has been revealed in the nucleus labelled wi...

journal_title：Experimental cell research

authors： Nakamura H,Morita T,Sato C

更新日期：1986-08-01 00:00:00

abstract：:Promyelocytic leukemia nuclear bodies (PML-NBs) are implicated in transcriptional regulation. Here we identify a novel transcriptional repressor, PML-associated repressor of transcription (PAROT), which is regulated in its repressor activity through recruitment to PML-NBs. PAROT is a Krüppel-associated box ( KRAB) zin...

journal_title：Experimental cell research

authors： Fleischer S,Wiemann S,Will H,Hofmann TG

更新日期：2006-04-01 00:00:00

abstract：:The ccl mutation in Paramecium tetraurelia reversibly and rapidly blocks cell cycle progression and DNA synthesis at the restrictive temperature. Progression through the cell cycle is blocked during both the G1 and S portions of the cell cycle, while at the restrictive temperature there is neither residual cell cycle ...

journal_title：Experimental cell research

authors： Rasmussen CD,Berger JD

更新日期：1984-12-01 00:00:00

abstract：:Integrins are heterodimeric transmembrane proteins that mediate substrate adhesion and migration but also the bidirectional transfer of information across the plasma membrane via their cytoplasmic domains. We addressed the question of whether the very short cytoplasmic tail of the alpha1 integrin subunit of alpha1beta...

journal_title：Experimental cell research

authors： Vossmeyer D,Kaufmann C,Löster K,Lucka L,Horstkorte R,Reutter W,Danker K

更新日期：2000-04-10 00:00:00

abstract：:Human calmodulin-like protein (CLP) is a calcium-binding protein down-regulated in a cell culture model of mammary tumorigenesis as well as in a majority of breast cancers in vivo. CLP down-regulation may be a result of the poorly differentiated state of these cell lines and tumors, or CLP expression may be incompatib...

journal_title：Experimental cell research

authors： Rogers MS,Kobayashi T,Pittelkow MR,Strehler EE

更新日期：2001-07-15 00:00:00

abstract：:Tob, a member of the Tob and BTG antiproliferative protein family, plays an important role in many cellular processes including cell proliferation. In this study, we have addressed molecular mechanisms regulating subcellular localization of Tob. Treatment with leptomycin B, an inhibitor of nuclear export signal (NES) ...

journal_title：Experimental cell research

authors： Maekawa M,Yamamoto T,Nishida E

更新日期：2004-04-15 00:00:00

abstract：:The fruit fly Drosophila melanogaster has recently emerged as an excellent system to investigate the genetics of cardiovascular development and disease. Drosophila provides an inexpensive and genetically-tractable in vivo system with a large number of conserved features. In addition, the Drosophila embryo is transpare...

journal_title：Experimental cell research

authors： McFaul CMJ,Fernandez-Gonzalez R

更新日期：2017-09-01 00:00:00

abstract：:Mitotic BHK21 cells were examined by immunofluorescence optical sectioning after staining with anti-vimentin. Throughout all stages of mitosis, intact 10-nm filaments were observed to form a cage around the mitotic spindle. These observations were confirmed by serial section electron microscopy which demonstrated asse...

journal_title：Experimental cell research

authors： Blose SH,Bushnell A

更新日期：1982-11-01 00:00:00

abstract：:Protein C23 (also called nucleolin or 100-kDa nucleolar protein) is a major nucleolar phosphoprotein involved in ribosome biogenesis. To determine the effects of protein C23 on preribosomal RNA (pre-rRNA) synthesis anti-C23 antiserum was microinjected into nuclei of Chironomus tentans salivary glands. Transcription wa...

journal_title：Experimental cell research

authors： Egyhazi E,Pigon A,Chang JH,Ghaffari SH,Dreesen TD,Wellman SE,Case ST,Olson MO

更新日期：1988-10-01 00:00:00

abstract：:The puromycin analog N6,N6-dimethyladenine (6-dimethylaminopurine or 6-DMAP) was found to inhibit meiosis reinitiation in starfish oocytes stimulated by the natural hormone 1-methyladenine. Increasing concentrations of this agent delayed and eventually blocked germinal vesicle breakdown. They were found to be effectiv...

journal_title：Experimental cell research

authors： Neant I,Guerrier P

更新日期：1988-05-01 00:00:00

abstract：:dNTP pools are quite low in immature oocytes of the starfish, expand during the 1-methyladenine-induced maturational process and thereafter reach a maximal level (approx. 35, 20, 15 and 5 fmoles/egg for dTTP, dCTP, dATP and dGTP, respectively) which is maintained in overmatured eggs. Maturing oocytes were inseminated ...

journal_title：Experimental cell research

authors： Nagano H,Okano K,Ikegami S

更新日期：1983-04-15 00:00:00

abstract：:The neurohormone serotonin (5HT) triggers meiosis reinitiation in oocytes of the pelecypod molluscs Spisula solidissima and Ruditapes philippinarum. However, while Spisula oocytes complete maturation, Ruditapes oocytes arrest in metaphase I. Anti-phosphotyrosine antibody revealed that serotonin triggered an early tyro...

journal_title：Experimental cell research

authors： Abdelmajid H,Rivailler P,Krantic S,Guerrier P

更新日期：1994-06-01 00:00:00

abstract：:Endocytosis and transport of bovine liver β-glucuronidase to lysosomes in human fibroblasts are mediated by two receptors: the well-characterized cation-independent mannose 6-phosphate receptor (IGF-II/Man6PR) and an IGF-II/Man6PR-independent receptor, which recognizes a Ser-Trp*-Ser sequence present on the ligand. Th...

journal_title：Experimental cell research

authors： Ramírez-Mata A,Michalak C,Mendoza-Hernández G,León-Del-Río A,González-Noriega A

更新日期：2011-10-01 00:00:00

abstract：:Experiments are described which show that the torsional oscillations arising in a strand of the slime mould, Physarum polycephalum, under certain conditions remain closely correlated to oscillations in cytoplasmic streaming. When this is the case, the direction of rotation is related to the direction of streaming by a...

journal_title：Experimental cell research

authors： Obendorf P,O'Sullivan RA

更新日期：1983-11-01 00:00:00