18F-FDG and 68Ga-DOTATATE PET/CT in von Hippel-Lindau Disease-Associated Retinal Hemangioblastoma.

Abstract:

:Retinal hemangioblastomas are highly vascular benign tumors that can be encountered either sporadically or within the von Hippel-Lindau (VHL) syndrome. We report a case of a VHL patient with retinal hemangioblastoma who underwent PET/CT scans using F-FDG and Ga-DOTATATE. The tumor showed low-level F-FDG and increased Ga-DOTATATE activity, suggesting cell-surface overexpression of somatostatin receptors. The presented case indicates the clinical applications of somatostatin receptor imaging with Ga-DOTA-conjugated peptides in detection and follow-up of VHL manifestations, screening of asymptomatic gene carriers, and in diagnosis of sporadic retinal hemangioblastomas, which may have similar features on MRI with other retinal tumors.

journal_name

Clin Nucl Med

authors

Papadakis GZ,Millo C,Jassel IS,Bagci U,Sadowski SM,Karantanas AH,Patronas NJ

doi

10.1097/RLU.0000000000001511

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

189-190

issue

3

eissn

0363-9762

issn

1536-0229

journal_volume

42

pub_type

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