Abstract:
PURPOSE:The purpose of this study was to assess left ventricular (LV) function by gated SPECT in acute hypothyroidism. METHODS:Thirty-eight acute hypothyroid patients without any cardiac disease and 40 healthy controls underwent gated SPECT at rest. Fourteen patients had a second examination during thyroxine replacement therapy. Gated SPECT was performed using Tc-99m sestamibi with 16 frames per cardiac cycle. The LV end-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF), peak ejection rate (PER), peak filling rate (PFR), and time to peak filling (TTPF) were measured by quantitative gated SPECT (QGS). Systolic wall thickening/motion was determined in 5 myocardial segments. RESULTS:Hypothyroid patients exhibited a decrease in PFR (222 +/- 52 EDV/s) and prolongation of TTPF (194 +/- 32 msec) as compared with controls (247 +/- 41 EDV/s and 179 +/- 17 msec, respectively; P < 0.05). During thyroxine therapy, the mean values for EDV (74 +/- 21 mL) and PFR (265 +/- 64 EDV/s) increased significantly in 14 follow-up patients (pretreatment values 67 +/- 18 mL and 219 +/- 50 EDV/s, respectively; P < 0.05). A significant difference was detected in the mean TTPF between the thyroxine group and the controls (195 +/- 35 msec vs 179 +/- 17 msec; P < 0.05). No significant differences were found in wall thickening and motion values (P > 0.05). CONCLUSION:Gated SPECT findings revealed diastolic dysfunction as indicated by a decrease in PFR and a prolongation in TTPF in patients with acute hypothyroidism.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Aydin M,Reyhan M,Sukan A,Yapar AF,Aktas Adoi
10.1097/01.rlu.0000252180.95540.64subject
Has Abstractpub_date
2007-02-01 00:00:00pages
94-100issue
2eissn
0363-9762issn
1536-0229pii
00003072-200702000-00003journal_volume
32pub_type
杂志文章abstract::Eleven patients, each with a painful solitary cold nodule of the thyroid were evaluated. All patients had subacute thyroiditis associated with neck pain and tenderness. Despite elevated sedimentation rate and increased thyroglobulin levels, nine of the patients were euthyroid, and I-131 uptake was normal in six. In al...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199511000-00008
更新日期:1995-11-01 00:00:00
abstract:ABSTRACT:A 13-year-old boy with mediastinal T-cell lymphoblastic lymphoma demonstrated an altered biodistribution with diffuse activity in subcutaneous white adipose tissue and decreased visceral activity on interim posttreatment FDG PET/CT. This altered biodistribution was attributed to administration of the chemother...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003340
更新日期:2021-03-01 00:00:00
abstract::A 54-year-old man with multiple endocrine neoplasia type 1 had previous history of parathyroid surgery and left thyroid lobectomy 5 years earlier, and was referred for recurrent hypoglycemic episodes. Ga-DOTATATE PET/CT had showed multiple lesions in the right lung, liver, and pancreas. Biopsy from pancreas revealed l...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002500
更新日期:2019-06-01 00:00:00
abstract::Parameters of systolic and diastolic function obtained from radionuclide ventriculography (RNV) were evaluated in nine cardiac allograft recipients. In 25 examinations, left end-diastolic volume (LEDV), cardiac output (CO), left ejection fraction (LEF), right ejection fraction (REF), heart rate (HR), peak filling rate...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198903000-00007
更新日期:1989-03-01 00:00:00
abstract:PURPOSE:This article illustrates the complementary nature of preoperative radionuclide parathyroid imaging and intraoperative rapid parathyroid hormone (PTH) assays in primary hyperparathyroid disease. The authors review the literature on these procedures and compare this protocol and its cost-effectiveness with those ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,评审
doi:10.1097/00003072-200003000-00002
更新日期:2000-03-01 00:00:00
abstract:ABSTRACT:A 63-year-old man with recent diagnosis of high-risk prostate adenocarcinoma was referred to our Nuclear Medicine Department for 18F-fluciclovine PET/CT to rule out metastasis in the setting of elevated serum prostate-specific antigen levels. The patient had previous history of nodular melanoma of the right ch...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003319
更新日期:2021-02-01 00:00:00
abstract::The diagnosis of unilateral renal vein thrombosis was established in a 50-year-old woman. A functional evaluation, by means of Tc-99m DTPA, was performed almost immediately, and at intervals up to nearly eight months later. Functional return of the involved kidney could be documented by plotting the ratio of affected ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198311000-00007
更新日期:1983-11-01 00:00:00
abstract::Abnormal accumulation of Tc-99m MDP in two metastatic lesions of the liver was observed in a patient with resected colon carcinoma. Single-photon emission computed tomography (SPECT) revealed characteristic marginal accumulation of Tc-99m MDP in both of those metastatic lesions. X-ray CT showed the corresponding margi...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198501000-00004
更新日期:1985-01-01 00:00:00
abstract::An unusual case is described in which in spite of clinical, scintigraphic and histologic findings strongly supportive of a diagnosis of "hyperacute rejection," recovery of renal function occurred. These findings are in contrast to the current literature in which it is generally accepted that a renal allograft showing ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198302000-00005
更新日期:1983-02-01 00:00:00
abstract:PURPOSE:Renal biopsy is crucial for management of lupus nephritis. However, it is invasive and can cause bleeding and infection. In our previous study, we developed a semiquantitative method for gallium renal imaging and demonstrated a good correlation between the left kidney-to-spine ratio (K/S ratio) and the results ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001108
更新日期:2016-06-01 00:00:00
abstract::Intense muscle localization of Tc-99m MDP to upper extremity musculature was noted three days following weight lifting exercises. This phenomenon is due to an unknown mechanism although several causative factors have been suggested. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198705000-00003
更新日期:1987-05-01 00:00:00
abstract::Solitary abnormalities located within the spine from 75 bone images with Tc-99m MDP were reviewed. For the sake of convenience, patients were grouped in three classes of age: 15-50, 51-65, and 66-90 years. In 67 cases, the diagnosis was apparent from clinical studies, x-ray examinations, or biopsies. In eight cases, n...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198807000-00013
更新日期:1988-07-01 00:00:00
abstract:PURPOSE:To investigate the significance of increased perfusion associated with some hepatic hemangiomata during radionuclide blood volume imaging. METHODS:Immediate dynamic planar projections and delayed SPECT imaging of a hepatic lesion were obtained after the administration of Tc-99m-labeled RBC. Scintigraphic data ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199708000-00006
更新日期:1997-08-01 00:00:00
abstract::A 21-year-old woman was admitted to our hospital after incidental detection of a left renal lesion on ultrasound scan. Abdominal contrast-enhanced CT scan revealed a moderately enhanced lesion in the left kidney and a round mass with slight enhancement in the retroperitoneum. FDG PET/CT imaging was performed for whole...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31825b2218
更新日期:2013-02-01 00:00:00
abstract::Unexplained false-positive accumulation of In-111 leukocyte in the gastrointestinal tract has been reported previously. In a pediatric population, uptake in the submandibular gland was noted in 19 of 42 children. This is believed to be a normal finding in children that is not seen in adults. In some of these 19 childr...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198711000-00010
更新日期:1987-11-01 00:00:00
abstract::We report a case of a 25-year-old woman presented with neutropenic fever after chemotherapy for the relapse of acute biphenotypic leukemia. Gallium-67 scintigraphy for the detection of infectious foci demonstrated a unique pattern of numerous foci with intense and varying-sized radioactivity spreading throughout the b...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318219ae3f
更新日期:2011-08-01 00:00:00
abstract::A 43-year-old man, previously submitted to right hepatectomy, right hepatic artery chemoembolization, and surgical resection of liver lesions, with well-differentiated and moderately differentiated hepatocellular carcinoma (HCC) confirmed by histopathology, underwent cholescintigraphy with Tc diisopropyliminodiacetic ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182815d28
更新日期:2014-01-01 00:00:00
abstract::A 17-year-old girl with a history of Hodgkin disease showed increased gallium accumulation in the region of the right hip and reduced uptake in the muscles of the right lower extremity. Increased gallium accumulation in the right hip was attributed to avascular necrosis and the reduced gallium activity was attributed ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000159922.84803.03
更新日期:2005-05-01 00:00:00
abstract::Renal neuroendocrine tumor (NET) is an extremely rarely occurring disease. The sporadic reports in the literature are mostly case reports, or less commonly small studies. In cases of metastatic disease from renal NET, there are no established therapies. We are reporting our experience with a patient with extensive oss...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001386
更新日期:2016-12-01 00:00:00
abstract::After prolonged androgen deprivation therapy, a subset of castrate-resistant prostate cancer patients will develop neuroendocrine prostate cancer (NEPC) associated with resistance to further hormonal therapy and frequent visceral metastases. Imaging the presence of somatostatin receptors on the cancer cell surface may...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000776
更新日期:2015-06-01 00:00:00
abstract::We presented a promising result of radionuclide therapy using Lu-PSMA and Lu-DOTATATE in a patient with prostatic adenocarcinoma and neuroendocrine differentiation. Functional imaging of somatostatin receptors in patients with metastatic castration-resistant prostate cancer may pave the way toward implementation of no...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002824
更新日期:2019-12-01 00:00:00
abstract::An 85-year-old woman who had an invasive ductal carcinoma of the breast and elevated alkaline phosphatases (420 U/L) was referred for Tc-99m MDP bone scintigraphy for initial evaluation of skeletal metastases. Bone symptoms were limited to chronic pain in both knees. A bone scan revealed pagetoid findings in both calc...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000247783.43949.c1
更新日期:2006-12-01 00:00:00
abstract::A case is reported in which a urinoma developed following a renal transplant. Dual isotope renography-cystography using Tc-99m DTPA and Ga-67 citrate revealed the diagnosis after ultrasonography and radiographic cystography were nondiagnostic. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198704000-00002
更新日期:1987-04-01 00:00:00
abstract::Fifteen patients who had bilateral mediofrontal hypoactivity and 30 control subjects without this SPECT anomaly underwent Tc-99m HMPAO brain SPECT imaging. Bilateral mediofrontal hypoactivity was found in various neurologic disorders, including subcortical arteriosclerotic encephalopathy, lacunar state, chronic alcoho...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199410000-00006
更新日期:1994-10-01 00:00:00
abstract::The literature on gallium imaging in mycosis fungoides is limited and conflicting. A case of mycosis fungoides with increased uptake of Ga-67 in clinically noninfected skin lesions is reported. The literature regarding mycosis fungoides and gallium imaging is reviewed. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198802000-00013
更新日期:1988-02-01 00:00:00
abstract::We report the case of a 45-year-old woman diagnosed with non-Hodgkin lymphoma. Six months after completion of R-CHOP, she relapsed, and 2 cycles of R-ESHAP were given, with a view to allograft transplant. One month later, F-FDG PET/CT revealed disease progression. Biopsy of lymph nodes showed reactive changes, without...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001083
更新日期:2016-03-01 00:00:00
abstract::A 49-year-old man presented with a left nasal cavity mass, biopsy of which revealed extranodal NK/T cell lymphoma. A PET-CT scan showed increased F-18 FDG uptake in the nasal mass, anterior mediastinal lymph nodes, and multiple subcutaneous nodular deposits in the chest wall, gluteal region, and right femoral areas. T...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31816a7a23
更新日期:2008-05-01 00:00:00
abstract::A 24-year-old female gymnast had a 3-month history of bilateral forearm pain. A Tc-99m MDP bone scan demonstrated focally increased activity in the radial shafts on blood pool and delayed images, characteristic of fatigue fractures. Fatigue fractures commonly occur in the lower extremities. Upper extremity fatigue fra...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199408000-00002
更新日期:1994-08-01 00:00:00
abstract::Numerous expected competencies of a chief nursing officer are outlined in this article including communication, ability to build relationships, expertise about the environment of healthcare and its future directions, leadership, expertise in business matters, combating bullying, encouraging shared decision making, and...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003221
更新日期:2020-08-11 00:00:00
abstract::A 52-year-old woman with right breast cancer was referred for 18F-fluoride whole-body PET/CT for the assessment of bone metastases. The peripheral i.v. access was not obtained after multiple attempts. The radiopharmaceutical was administered by oral route. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000250
更新日期:2013-12-01 00:00:00