Abstract:
:After prolonged androgen deprivation therapy, a subset of castrate-resistant prostate cancer patients will develop neuroendocrine prostate cancer (NEPC) associated with resistance to further hormonal therapy and frequent visceral metastases. Imaging the presence of somatostatin receptors on the cancer cell surface may provide a readily available, noninvasive means to distinguish adenocarcinoma from NEPC. This distinction is important for therapeutic decision making and may open the door for developing novel radionuclide targets for the treatment of this aggressive subtype of prostate cancer. We describe a case of NEPC successfully imaged using In-labeled octreotide.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Hope TA,Aggarwal R,Simko JP,VanBrocklin HF,Ryan CJdoi
10.1097/RLU.0000000000000776subject
Has Abstractpub_date
2015-06-01 00:00:00pages
540-1issue
6eissn
0363-9762issn
1536-0229journal_volume
40pub_type
杂志文章abstract:PURPOSE:The present study aimed to determine the predictive value of the heart-liver uptake ratio (H/L ratio) of rectally administered (201)Tl scintigraphy for hepatic decompensation, which was conducted in 107 patients with cirrhosis. METHODS:We retrospectively assessed the predictive value of a noninvasive parameter...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31827087e3
更新日期:2013-03-01 00:00:00
abstract::An unusual posterior extension of the right lobe of the liver mimicked a retroperitoneal mass on CT scanning. Tc-99m SC SPECT imaging documented normal liver uptake within the suspected mass, proving that it was an anomalous extension of the right lobe of the liver rather than a pathologic lesion. This unusual liver v...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199008000-00008
更新日期:1990-08-01 00:00:00
abstract::In this study, we report the results of using fluorine deoxyglucose positron emission tomography/computed tomography (FDG PET/CT) to guide the antifungal therapy against chronic disseminated candidiasis in patients with acute leukemia. Three adult patients were enrolled in this study. All patients underwent a series o...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181e4db84
更新日期:2010-08-01 00:00:00
abstract::Tc-99m sulfur colloid has been shown to be accurate in the detection of intrapulmonary bleeding (1,2). The present example demonstrates the usefulness of Tc-99m sulfur colloid in identifying an unusual manifestation of intrathoracic hemorrhage. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198411000-00020
更新日期:1984-11-01 00:00:00
abstract::Stress fractures are a common injury in long-distance runners, and typically involve the lower extremities. Although relatively rare, pubic ramus stress fractures also occur, primarily in female runners. Bone imaging visualized a pubic stress fracture and a tibial stress fracture in a female long-distance runner with ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198612000-00005
更新日期:1986-12-01 00:00:00
abstract::We present a case of a right skull base paraganglioma detected using F-choline PET/CT in a 63-year-old man. The F-choline PET/CT scan was performed to assess a known prostate cancer. In addition, the scan demonstrated a mildly choline-avid (SUVmax, 3.8) tumor within the carotid sheath of the right skull base, extendin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002708
更新日期:2019-09-01 00:00:00
abstract::SPECT imaging with I-123 IMP or Tc-99m HMPAO was performed in two patients with Creutzfeldt-Jakob disease to evaluate abnormalities in brain perfusion. In the first patient, there was decreased perfusion of the left frontal, parietal, and temporal lobes. CT and MRI were negative. In the second patient, there was patch...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199603000-00010
更新日期:1996-03-01 00:00:00
abstract::Soft tissue localization of radiotracer on bone scintigraphy may result in false-positive interpretations, if the activity overlies a bony structure. A case is presented in which special views and follow-up clarified the soft tissue nature of focal uptake in arm and axilla. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199303000-00004
更新日期:1993-03-01 00:00:00
abstract::Whereas benign leiomyoma of the uterus (fibroid) is very common, malignant degeneration of such fibroids to leiomyosarcoma is rare. Anatomical imaging with CT or MRI cannot differentiate between larger leiomyoma and leiomyosarcoma. Imaging with F-FDG PET/CT can be helpful in differentiating the two. High-grade F-FDG u...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001330
更新日期:2016-10-01 00:00:00
abstract:UNLABELLED:Interpretation of radionuclide arthrograms (RNA) of the knee after total knee joint replacement (TKR) may be difficult because of the lack of sufficient anatomic reference information. Additional transmission images may provide the necessary reference information required for correct interpretation of RNA of...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199710000-00001
更新日期:1997-10-01 00:00:00
abstract::Single-photon emission computed tomography has been proven to detect more abnormalities than planar bone scintigraphy in patients with low back pain (LBP). Both 180 degrees and 360 degrees acquisitions were performed in 24 patients with LBP to determine whether the shorter 180 degrees posterior SPECT is as accurate fo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199306000-00004
更新日期:1993-06-01 00:00:00
abstract::Extrapulmonary small cell carcinoma (SCC) is an uncommon malignancy. A 57-year-old man was referred because of a 1-month history of left lumbago. MR images showed an ovoid tumor in the left adrenal gland. FDG PET/CT showed intense FDG uptake of the left adrenal tumor with thrombosis of the left renal vein. The patient...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318286bfcc
更新日期:2013-11-01 00:00:00
abstract::Interstitial pneumonia is one of the many causes of a scintigraphic ventilation-perfusion (V/Q) mismatch. To evaluate the morphologic features of V/Q mismatched areas in patients with interstitial pneumonia, we correlated the findings on lung scintigraphy using Kr-81m and Tc-99m MAA with CT scan findings. Of 41 patien...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199703000-00006
更新日期:1997-03-01 00:00:00
abstract::A variety of sequelae of elevated calcium levels are encountered in patients with underlying primary hyperparathyroidism, including stone formation such as calculi in the urinary tract and sialoliths in the salivary glands and ducts. We present a case of a 54-year-old woman with fatigue, myalgia, and poor concentratio...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001863
更新日期:2017-12-01 00:00:00
abstract::Metastatic calcifications according to histopathologic and scintigraphic findings have been well-defined. The authors report a postoperative case of hyperparathyroidism with multiple metastatic calcifications in the lung, kidney, stomach, heart, and vessels that were primarily detected by bone scintigraphy and demonst...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199202000-00010
更新日期:1992-02-01 00:00:00
abstract::Focal radionuclide accumulation of Tc-99m sulfur colloid (SC) and tc-99m macroaggregated albumin (MAA) in the liver has been reported in both inferior and superior vena caval obstruction. We studied a patient with uniform radionuclide accumulation of Tc-99m MAA in the liver during lung scintigraphy. In this patient, b...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198308000-00009
更新日期:1983-08-01 00:00:00
abstract:PURPOSE:The benefit of time-of-flight (TOF) information in PET oncology studies is well established, demonstrating improved signal-to-noise ratio and enhanced lesion detection. In cardiac PET studies, tracer distribution and study interpretation differ substantially from oncology PET, and the benefit of TOF is less est...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001441
更新日期:2017-02-01 00:00:00
abstract::Ventriculoperitoneal shunt malfunction is common in patients after shunt surgery. Imaging is done to reveal the underlying cause and confirm the diagnosis. Shunt infection is one of the common causes of shunt malfunction. FDG PET CT is an accepted infection imaging tool and can be used to diagnose shunt infection accu...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002756
更新日期:2020-03-01 00:00:00
abstract::We reported a 24-year-old woman who developed a movement disorder of mouth and limbs during systemic lupus erythematosus. Brain MRI did not find any abnormalities. Increased FDG uptake in basal ganglia was found using FDG PET/CT brain scan. The symptoms remitted after therapy and the activities of the original hyperme...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001450
更新日期:2017-01-01 00:00:00
abstract::We report a 58-year-old man whose incidentally discovered papillary thyroid carcinoma in the left lobe showed high FDG and low FLT uptake on PET/CT. The SUVmax was 19.7 for FDG and 3.0 for FLT. The Ki-67 labeling index of the tumor was 1.9%. Thus, the low FLT uptake might be attributed to the low proliferative activit...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318252d80f
更新日期:2012-06-01 00:00:00
abstract:ABSTRACT:A 51-year-old man with a palpable neck mass and elevated parathyroid hormone was referred to our department for parathyroid scintigraphy. After injection of 740 MBq 99mTc-MIBI, a dual-phase scan was obtained, which revealed a persistent and intense focal hyperactivity in the left side of the neck (compatible w...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003448
更新日期:2021-02-01 00:00:00
abstract::Magnetic resonance imaging (MRI) was compared with radionuclide scintigraphy (RNS) in 16 patients with renal transplants undergoing renal failure to determine which modality could best discriminate between rejection, acute tubular necrosis (ATN), and cyclosporin nephrotoxicity (CN). Although all rejecting transplants ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198804000-00005
更新日期:1988-04-01 00:00:00
abstract::Primary endometrial hepatoid adenocarcinoma is a rare tumor. We present a case of a 64-year-old woman with vaginal bleeding for 2 months and a markedly elevated serum α-fetoprotein of 3931 ng/mL. Hysteroscopic segmental curettage revealed endometrial adenocarcinoma. A pelvic MRI was performed for local tumor invasion,...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002538
更新日期:2019-07-01 00:00:00
abstract::A 35-year-old man presented with right lower extremity numbness and weakness. CT demonstrated an irregular left parietal hypoattenuation with a punctuate calcification. MRI revealed a T1 low signal and T2 high signal lesion with extensive surrounding edema. Gadolinium-enhanced MRI showed an irregular enhancing lesion....
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182708352
更新日期:2012-12-01 00:00:00
abstract::The efficacy and merit of testicular imaging, utilizing Tc-99m pertechnetate, were studied prospectively in a group of patients who presented with acute onset of scrotal pain. Consecutive admissions were studied. All were managed according to the likelihood of the problem being testicular torsion, which was determined...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198606000-00002
更新日期:1986-06-01 00:00:00
abstract::A 17-year-old girl with a history of Hodgkin disease showed increased gallium accumulation in the region of the right hip and reduced uptake in the muscles of the right lower extremity. Increased gallium accumulation in the right hip was attributed to avascular necrosis and the reduced gallium activity was attributed ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000159922.84803.03
更新日期:2005-05-01 00:00:00
abstract::Patients with ascites are known to have complications such as pleural effusions and hernias. Special diagnostic procedures are occasionally necessary to determine the nature of the abnormality and to determine the corrective medico-surgical approach. The two cases described illustrate the usefulness of intraperitoneal...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199002000-00007
更新日期:1990-02-01 00:00:00
abstract::SPECT findings in a very rare case of primary amyloidosis localized in the laryngotracheobronchial area are reported. SPECT using Tc-99m PYP revealed widespread uptake in the larynx and the entire tracheobronchial tree up to the subsegmental divisions; the areas corresponded to diffuse thickening and calcification of ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199308000-00011
更新日期:1993-08-01 00:00:00
abstract:PURPOSE:We investigated the incidence of lymph node metastasis in gastrointestinal stromal tumor (GIST) patients in our PET/CT database. The demographic data and characteristics of the primary tumor were evaluated in GIST patients with or without lymph node metastasis. MATERIALS AND METHODS:We reviewed our PET/CT data...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318219ad31
更新日期:2011-08-01 00:00:00
abstract::Stress-lymphoscintigraphy evaluates the effects of exercise on lymph drainage. Results may predict outcomes of complex physical therapy as a first-line lymphedema treatment. Microsurgical approaches are best in patients with lymphangectasia or dermal backflow. Lymphatic pathway mapping helps plan lympho-venous anastom...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002560
更新日期:2019-08-01 00:00:00