Utility of FDG PET/CT in guiding antifungal therapy in acute leukemia patients with chronic disseminated candidiasis.

Abstract:

:In this study, we report the results of using fluorine deoxyglucose positron emission tomography/computed tomography (FDG PET/CT) to guide the antifungal therapy against chronic disseminated candidiasis in patients with acute leukemia. Three adult patients were enrolled in this study. All patients underwent a series of PET/CT scans during the course of antifungal therapy. Antifungal therapy was modified based on the change of the FDG activity in the known sites of the fungal infection. With the guidance of FDG PET/CT, all 3 patients achieved favorable outcomes with long-term follow-up. FDG PET/CT appeared to be a valuable modality in designing proper antifungal therapy against chronic disseminated candidiasis in patients with acute leukemia.

journal_name

Clin Nucl Med

authors

Xu B,Shi P,Wu H,Guo X,Wang Q,Zhou S

doi

10.1097/RLU.0b013e3181e4db84

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

567-70

issue

8

eissn

0363-9762

issn

1536-0229

pii

00003072-201008000-00001

journal_volume

35

pub_type

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