11C-4DST PET/CT Imaging of Cardiac Sarcoidosis: Comparison With 18F-FDG and Cardiac MRI.

Abstract:

:A 75-year-old woman with a history of sarcoidosis presenting with low cardiac output and complete right bundle-branch block underwent 4'-[methyl-C]-thiothymidine (4DST) PET/CT after cardiac MRI and FDG PET/CT for the evaluation of suspected cardiac sarcoidosis (CS) before treatment. Cardiac MRI revealed late gadolinium enhancement on the anterior-to-lateral and posterior wall, indicating CS. FDG uptake was shown on the anterior-to-lateral wall, but not on the posterior wall. In contrast, 4DST uptake was demonstrated on both anterior-to-lateral and posterior walls. Use of 4DST appears promising for detecting CS without dietary restriction, due to the lack of physiological uptake in myocardium.

journal_name

Clin Nucl Med

authors

Hotta M,Minamimoto R,Kubota S,Awaya T,Hiroi Y

doi

10.1097/RLU.0000000000002059

subject

Has Abstract

pub_date

2018-06-01 00:00:00

pages

458-459

issue

6

eissn

0363-9762

issn

1536-0229

journal_volume

43

pub_type

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