Abstract:
AIM:to evaluate the treatment response in patients with recurrent colorectal cancer (CRC) using FDG PET/CT. MATERIALS AND METHODS:a total of 32 recurrent CRC patients (21 males, 11 females; mean age, 52.8 years) were included in this retrospective study. All patients underwent a baseline and follow-up FDG PET/CT scans after chemotherapy. Of 32 patients, 23 patients had follow-up carcinoembryonic antigen (CEA) levels. RESULTS:on qualitative analysis of baseline and follow-up FDG PET/CT studies, there were 20 nonresponders and 12 were responders. On quantitative analysis, there were 19 nonresponders and 13 were responders. In responders, baseline and follow-up mean SUV(max) were 11.8 ± 10.1 and 3.7 ± 4.1, respectively (significant decrease, P = 0.001). Among nonresponders, baseline and follow-up mean SUV(max) were 8.1 ± 5.2 and 14.1 ± 9.0, respectively (significant increase, P = 0.003). There was no association between response and different factors like age, sex, diagnosis, extent of the lesions, and number of lesions. CONCLUSION:FDG PET/CT appears to be useful modality in evaluating chemotherapy response and can differentiate responders from nonresponders in recurrent CRC patients.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Shamim SA,Kumar R,Shandal V,Halanaik D,Kumar G,Bal CS,Malhotra Adoi
10.1097/RLU.0b013e3181feeb48subject
Has Abstractpub_date
2011-01-01 00:00:00pages
11-6issue
1eissn
0363-9762issn
1536-0229pii
00003072-201101000-00003journal_volume
36pub_type
杂志文章abstract::Xerostomia is a significant morbidity of radiation treatment in the management of head and neck cancers. To preserve salivary function, a surgical technique has been developed that involves the transfer of one submandibular gland to the ipsilateral submental space, where it can be shielded during radiation therapy. F-...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318219ac4a
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:To analyze the biodistribution of Ga-DOTA-TATE in the normal tissues and uptake in benign, indeterminate, and malignant lesions in a population of patients with known neuroendocrine tumors (NET) using semiquantitative standardized uptake values (SUV) measurements. METHODS:One hundred four consecutively scanned...
journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/RLU.0000000000001100
更新日期:2016-06-01 00:00:00
abstract::Three cases involving renal scans that showed both severe photopenia and also increase in uptake in a rim surrounding the renal graft are presented. As previously mentioned in the literature, the bad prognostic import of photopenia is confirmed. The increased rim of activity has been rarely mentioned in the literature...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198508000-00012
更新日期:1985-08-01 00:00:00
abstract::Erlotinib is a reversible epidermal growth factor receptor tyrosine kinase inhibitor used to treat advanced non-small cell lung carcinoma patients who have shown progression on at least 1 prior chemotherapy regimen. Most of the patients on erlotinib show cutaneous adverse effects. We report the 18F-FDG PET/CT findings...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000586
更新日期:2015-04-01 00:00:00
abstract::The value of using heparin as a pharmacologic intervention to induce a positive scintiscan was studied in a patient with chronic occult gastrointestinal bleeding. When all standard diagnostic tests (upper and lower gastrointestinal series, upper and lower endoscopy, and conventional noninterventional Tc-99m RBC imagin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198404000-00003
更新日期:1984-04-01 00:00:00
abstract::Anthracyclines are one of the most commonly used and potent chemotherapeutic agents. Doxorubicin (Adriamycin) is one common anthracycline used to treat many solid tumors including breast, sarcomas, gynecologic and hematological malignancies, such as leukemias and lymphomas. However, its use is often limited due to dos...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,评审
doi:10.1097/RLU.0b013e3181b7d76f
更新日期:2009-11-01 00:00:00
abstract::Pulmonary artery involvement can occur in about half of the patients suffering Takayasu arteritis. Increased FDG activity in the aorta and its main branches in patients with Takayasu arteritis on PET/CT had been well-reported. However, the FDG PET/CT appearance of pulmonary artery involvement in Takayasu arteritis is ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003149
更新日期:2020-09-01 00:00:00
abstract::A 50-year-old woman presented a painless left submandibular mass. She had history of partial thyroidectomy for nodular goiter. A radioiodine whole-body scan showed tracer accumulation in the mass, which connected with the thyroid remnant. The left submandibular mass was resected, and the pathological examination demon...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001226
更新日期:2016-06-01 00:00:00
abstract::Two patients with myocardial sarcoidosis are presented, both of whom underwent SPECT imaging with Tl-201 and Ga-67. The first had Ga-67 myocardial uptake with a Tl-201 defect, which disappeared with corticosteroid therapy. The second had multiple Tl-201 defects without Ga-67 uptake, which persisted despite corticoster...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199006000-00009
更新日期:1990-06-01 00:00:00
abstract::Optimal scan time of F-fluorocholine (FCH) PET/CT for localization of hyperfunctioning parathyroid glands is poorly documented. We report a small series of 9 histologically proven hyperfunctioning parathyroid gland with heterogeneous temporal uptake profile. Thirty-minute dynamic acquisition starting just after F-fluo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002132
更新日期:2018-07-01 00:00:00
abstract::Abnormal accumulation of Tc-99m MDP in two metastatic lesions of the liver was observed in a patient with resected colon carcinoma. Single-photon emission computed tomography (SPECT) revealed characteristic marginal accumulation of Tc-99m MDP in both of those metastatic lesions. X-ray CT showed the corresponding margi...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198501000-00004
更新日期:1985-01-01 00:00:00
abstract::Pituitary macroadenoma constitutes a frequently misdiagnosed benign tumor. We report herein a case where such macroadenoma, a prolactinoma, was incidentally discovered in a 63-year-old man who had been referred to F-FDG PET and F-FDOPA PET imaging for a pharmacoresistant epilepsy. An increased uptake was documented fo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001721
更新日期:2017-08-01 00:00:00
abstract::Tc-99m hydroxymethylene disphosphonate administered for skeletal scintigraphy may be seen in the extraosseous tissues for various etiologies. This report presents similar abnormal lower extremity skeletal muscle uptake in 2 patients status postorthotopic liver transplant. Although the history and scintigraphic appeara...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200411000-00004
更新日期:2004-11-01 00:00:00
abstract::Tc-99m galactosyl-neoglycoalbumin (NGA) is a new liver imaging agent that specifically binds to a hepatocyte specific membrane receptor, the hepatic binding protein. Scintigraphy with Tc-99m NGA is a noninvasive method that provides functional images of the liver. This report deals with one case of fulminant hepatic f...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199504000-00009
更新日期:1995-04-01 00:00:00
abstract::We report on an incidental detection of a meningioma on [F]-2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (F-FMAU) PET/CT scan that was performed during a prospective investigation of F-FMAU PET/CT for targeted biopsy of potential sites of tumor in men with suspected prostate cancer based on elevated prostate-spe...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002123
更新日期:2018-07-01 00:00:00
abstract::A woman with bilateral breast cancer treated with bilateral mastectomies, implant reconstructions, chemotherapy, and hormonal therapy underwent FDG PET/CT imaging. Imaging demonstrated sternal, nodal, and lung lesions which were stable or slowly increasing, as well as a parasternal chest wall mass which was enlarging ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31828e98dc
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:In recent years, several case reports have described venous thromboembolism (VTE) on FDG PET/CT. In this short communication, we present results from a proof-of-concept pilot study aimed at providing some preliminary data on the efficacy of FDG PET/CT in prospective patients with suspected VTE. PATIENTS AND ME...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000453
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:Fully automated synthesis of 11C-labeled 2β-carbomethoxy-3β-(4-fluorophenyl)tropane (11C CFT) as a dopamine transporter positron emission tomography (PET) tracer is performed with Sep-Pak purification, which cannot separate 11C CFT from nor-β-CFT and will result in the residual precursor nor-β-CFT in the final ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/RLU.0b013e31824c5fae
更新日期:2012-08-01 00:00:00
abstract::Hypertrophic pseudarthrosis was studied with Tc-99m MDP and Ga-67 citrate in 11 patients. Two of the 11 pseudarthroses were complicated by infection. A high concentration of both radiopharmaceuticals was obtained at all 11 sites and their distribution patterns were identical. It was therefore impossible to distinguish...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198302000-00001
更新日期:1983-02-01 00:00:00
abstract::Renal vein thrombosis is a rare complication of renal transplantation. The scintigraphic features of a documented case of renal vein thrombosis studied with Tc-99m DTPA and the differential diagnosis relevant to these findings are discussed. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198806000-00009
更新日期:1988-06-01 00:00:00
abstract::An 18F-FDG PET/CT scan was performed in a 26-year-old man with a known alveolar rhabdomyosarcoma for staging. The PET/CT scan showed abnormally increased FDG activity involving almost all bones in the imaged regions. In contrast, 99mTc-MDP whole-body bone scan demonstrated only very limited bone metastases. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000277
更新日期:2013-12-01 00:00:00
abstract::SPECT findings in a very rare case of primary amyloidosis localized in the laryngotracheobronchial area are reported. SPECT using Tc-99m PYP revealed widespread uptake in the larynx and the entire tracheobronchial tree up to the subsegmental divisions; the areas corresponded to diffuse thickening and calcification of ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199308000-00011
更新日期:1993-08-01 00:00:00
abstract::A 46-year-old female patient with a mediastinal neuroendocrine carcinoma complicated by superior vena cava syndrome was referred for a bone metastatic workup. Bone scan with SPECT/CT showed several vertebral fixations without alterations on the unenhanced CT, but a CT scan with injection of contrast media showed verte...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182a20daa
更新日期:2013-11-01 00:00:00
abstract::We present a case of a 55-year-old man with a history of poorly differentiated metastatic thyroid cancer, which is rare and shows aggressive behavior. The patient had radioactive iodine-negative multiple metastasis on F-FDGPET/CT, therefore Ga-DOTATATE and Ga-PSMA PET/CT were performed whether an opportunity exist for...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003362
更新日期:2020-11-03 00:00:00
abstract::A 2-year-old girl with cardiorespiratory distress and suspected pulmonary embolism (PE) was referred for urgent lung perfusion scintigraphy, proven negative for perfusion defects but unexpectedly revealing an enlarged orthotopic thyroid. This finding was, under the circumstances, considered as suggestive of thyroid st...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31829af5ed
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:This study aims to investigate the feasibility of using simultaneous breast MRI and PET to assess the synergy of MR pharmacokinetic and fluorine-18 fluorodeoxyglucose (F-FDG) uptake data to characterize tumor aggressiveness in terms of metastatic burden and Ki67 status. METHODS:Twelve consecutive patients unde...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001254
更新日期:2016-08-01 00:00:00
abstract::Two cases of unilateral septic sacro-iliitis are reported. Importance of the anterior view of sacroiliac joints on the radionuclide bone scan is stressed. Limitation of the posterior view in evaluation of sacroiliac joints may lead to misdiagnosis and false negative results in unilateral sacro-illiac disease. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198309000-00006
更新日期:1983-09-01 00:00:00
abstract::Giant cell tumor of tendon sheath (GCTTS) is benign mesenchymal neoplasm, and it rarely induces hypophosphatemia. We report a 49-year-old woman with suspicious tumor-induced osteomalacia underwent Ga-DOTA-TATE PET/CT to identify potential causative tumor, which showed a hypermetabolic soft tissue nodule in the right f...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002550
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:This study was performed to evaluate the diagnostic accuracy of brain perfusion SPECT in patients visiting the cognitive disorder clinic for initial evaluation using 3D-SSP compared with using standard transaxial section. MATERIALS AND METHODS:Standard transaxial section displays and 3D-SSP z-score maps obtain...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.rlu.0000246818.24566.54
更新日期:2006-12-01 00:00:00
abstract::ITP (idiopathic thrombocytopenic purpura) causes rapid sequestration and destruction of thrombocytes by the spleen, liver, bone marrow, and reticuloendothelial elements of other organs. The usefulness of multiple radionuclide functional imaging procedures in the management of a 34-year-old woman with chronic ITP, two ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199208000-00009
更新日期:1992-08-01 00:00:00