Abstract:
PURPOSE:We investigated the incidence of lymph node metastasis in gastrointestinal stromal tumor (GIST) patients in our PET/CT database. The demographic data and characteristics of the primary tumor were evaluated in GIST patients with or without lymph node metastasis. MATERIALS AND METHODS:We reviewed our PET/CT database from January 1, 2007 to November 30, 2010 by using keyword search, and identified GIST with lymph node metastasis according to our standard of reference. Statistical analysis was conducted between GIST group with or without lymph node metastasis based on the age, sex, primary tumor size, and primary tumor location. RESULTS:A total of 29 GIST patients were found in our database. Six of them had lymph node metastasis, corresponding to 20.7%. When considering only the adult patients, the incidence was 17% (5 out of 28). There were 4 males and 1 female, with the mean age of 66.8 years old, which was 8 years older than the group without lymph node metastasis. Of the 5 adult metastasis patients, 4 had their primary tumor located at very rare sites other than stomach or small bowel. Statistical analysis using Fisher exact test of rare location showed significance between the 2 groups with P = 0.004. The mean size of the primary tumor in the group with lymph node metastasis was 5.2 cm, which was 2.9 cm less than the group without metastasis. No statistical significance was found in age, sex, or size of primary tumor between the 2 groups. CONCLUSION:The incidence of lymph node metastasis in GISTs in our database is 20.7%, which is surprisingly higher than we thought from other previous studies. In contrast to the group without lymph node metastasis, these patients tend to be of older ages and had rare location of the primary tumor. This result supports further study with larger sample size.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Gong N,Wong CS,Chu YCdoi
10.1097/RLU.0b013e318219ad31subject
Has Abstractpub_date
2011-08-01 00:00:00pages
678-82issue
8eissn
0363-9762issn
1536-0229pii
00003072-201108000-00009journal_volume
36pub_type
杂志文章abstract::A 57-year-old woman initially presented with the acute onset of low back pain after gardening. Plain film at that time was reported as showing Scheurmann's disease of the lumbar spine. The pain resolved slowly, but recurred acutely after minimal trauma 5 months later. Bone scintigraphy revealed increased uptake in L4 ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318149ee54
更新日期:2007-10-01 00:00:00
abstract:PURPOSE OF THE REPORT:Extrahepatic bile duct (EHD) cancer varies in uptake of FDG. The aim of the present study was to determine the role of glucose transporter (GLUT) 1 and hexokinase (HK) 2 in the glucose metabolism of EHD cancer cells using immunohistochemistry and 18F-FDG PET/CT. METHODS:Twenty-six patients with E...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000640
更新日期:2015-03-01 00:00:00
abstract::Urinothorax or urothorax, the presence of urine in the pleural space, is a rare complication of percutaneous access to the kidney for the management of complex renal and proximal ureteral calculi and ureteropelvic junction obstruction. Other causes such as blunt renal trauma, ureteral instrumentation, or ureteral surg...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31818bf181
更新日期:2008-12-01 00:00:00
abstract::A case of false-negative Tc-99m MDP bone scintigrams, taken at one and two weeks for pathologic fractures in a patient with metabolic bone disease and a super-scan appearance, is described. The patient had renal osteodystrophy, and postparathyroidectomy hypocalcemia. Postoperative seizures caused multiple pathologic f...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198707000-00004
更新日期:1987-07-01 00:00:00
abstract::We report a case of mucinous cystic neoplasm which showed FDG accumulation in its cyst wall. MRI revealed that this tumor had repeated intracystic hemorrhage. Inhomogeneous FDG accumulation was found in the cyst wall. The epithelium was focally denuded and ovarian-like stroma with macrophage migration, which phagocyto...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181feedd9
更新日期:2011-01-01 00:00:00
abstract:AIM:The aim of the study was to evaluate if there is a prognostic importance of pretreatment Tc-MAA uptake of liver lesion of patients who received Y selective internal radiation therapy (SIRT) treatment for hepatocellular cancer (HCC) or not. METHODS:Nineteen patients (5 female and 14 male patients; mean age, 64.5 ± ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31828162e8
更新日期:2013-04-01 00:00:00
abstract:ABSTRACT:We report the case of a 45-year-old woman with a history of right breast reconstruction with silicone implant for breast cancer. An 18F-FDG PET/CT performed several years later revealed the presence of 18F-FDG-avid nodules at the periphery of the silicone implant, in the right internal mammary chain, and in th...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003422
更新日期:2021-02-01 00:00:00
abstract::For better delineation of regional ventilation abnormalities, a lateral-view imaging has been employed when one or more areas of abnormal retention were visible in posterior views of 133Xe washout images. It is technically simple to obtain lateral views during the 133Xe washout phase. The resulting images were found t...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197902000-00001
更新日期:1979-02-01 00:00:00
abstract::Reduced cortical benzodiazepine receptor binding potential in late images of I-iomazenil SPECT indicates neuronal damage in the cortex. We present the case of a 31-year-old woman with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) who had focal seizures in the right hand. FLA...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318299610f
更新日期:2014-06-01 00:00:00
abstract::A 23-year-old man with Dyke-Davidoff-Masson syndrome (DDMS) was admitted to the hospital with increasing frequency of epileptic seizures. Physical examination revealed mental retardation, left facial asymmetry, and left-sided spastic hemiparesis. Dysdiadochokinesia on the left upper limb was detected, and there was no...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000890
更新日期:2015-09-01 00:00:00
abstract::Pheochromocytomas/paragangliomas (PGLs) are rare tumors and mostly benign. We report on a 32-year-old woman with metastatic PGL who was first diagnosed with an abdominal PGL at the age of 12 years. She soon developed metastatic disease and received several treatments including external beam radiation and chemotherapy....
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001116
更新日期:2016-05-01 00:00:00
abstract::Pituitary macroadenoma constitutes a frequently misdiagnosed benign tumor. We report herein a case where such macroadenoma, a prolactinoma, was incidentally discovered in a 63-year-old man who had been referred to F-FDG PET and F-FDOPA PET imaging for a pharmacoresistant epilepsy. An increased uptake was documented fo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001721
更新日期:2017-08-01 00:00:00
abstract::A 51-year-old man presented with cough and pain in his upper chest for 1 week. Chest CT showed an ill-defined right paratracheal mass with slight enhancement in the upper mediastinum. A FDG PET/CT was performed showing focal increased FDG uptake with SUVmax of 4.7 in the mass. The mass was excised surgically. Histopat...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002860
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:Gliomas constitute the most frequent primary brain tumors. Glioblastoma, the most common and malignant glioma in adults, has dismal prognosis with any current therapy. On the other hand, low-grade gliomas, the second most common type of gliomas, are potentially curative with appropriate treatment. METHODS:We c...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,meta分析
doi:10.1097/RLU.0000000000002654
更新日期:2019-11-01 00:00:00
abstract::Incidental findings on PET CT studies are common. The distribution of Ga-DOTATATE is dependent on cell surface expression of somatostatin receptors, which may be pathologic or physiologic. Osteoporosis circumscripta is the early lytic phase of Paget disease associated with well-defined osteopenia, most commonly seen w...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002567
更新日期:2019-06-01 00:00:00
abstract::The costosternoclavicular region is not a common bone metastasis site, and symmetrical involvement is even rarer. Increased tracer uptake in the manubrium and sternoclavicular joints usually gives the typical "bull-horn" appearance seen in SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis). Herei...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001061
更新日期:2016-02-01 00:00:00
abstract::Anatomic localization of spine lesions, shown by Tc-99m phosphonate SPECT, to facet joint or pedicle is often difficult due to limitations in resolution. Indirect localization, relating lesion position on sagittal reconstruction to the adjacent visible vertebral bodies and also to patient spine radiographs, might be r...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199107000-00002
更新日期:1991-07-01 00:00:00
abstract::Hemangiomas are easily, quickly and relatively noninvasively detected using whole-body imaging with Tc-99m labeled RBCs. A case in which this method was used to confirm known lesions and detect additional unsuspected lesions is described. This method can also be useful in the detection and evaluation of other types of...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198610000-00012
更新日期:1986-10-01 00:00:00
abstract::Growth arrest lines (also referred to as Harris lines) refer to dense metaphyseal trabecular lines, perpendicular to the long axis of the bone. The phenomenon is seen only in patients with immature skeletal structure after periods of nutritional insufficiency, illness, and prolonged immobilization or bisphosphonates a...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31825ae89d
更新日期:2012-10-01 00:00:00
abstract::A patient with disseminated osseous metastases due to breast cancer reported multifocal pain. Because of persisting pain after a first cycle of chemotherapy, 1,295 MBq Re-186 HEDP was administered intravenously. Excellent pain relief was observed. Subsequently, the patient received further combined chemotherapy and Re...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199808000-00001
更新日期:1998-08-01 00:00:00
abstract::Thoracic pain is an entity that can be difficult to diagnose etiologically. Once the cardiac origin has been ruled out, the rheumatologic, neoplastic, and infectious causes have to be taken into account. We present the case of a patient with atypical chest pain after triple-bypass surgery in whom F-FDG PET/CT scan sho...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002237
更新日期:2018-10-01 00:00:00
abstract::A 17-year-old girl underwent F-NaF PET/CT to evaluate bone pain after an accident. The images did not identify any osseous lesion. However, there was a focally increased activity in the left upper chest, which corresponded to a partially calcified soft tissue mass in the mediastinum, suggestive of malignancy. The resu...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001343
更新日期:2016-10-01 00:00:00
abstract::A previously healthy 3-year-old girl developed rhinorrhea, painful right neck swelling, and fever. Contrast-enhanced CT of the neck revealed cervical lymphadenopathy, for which lymphoma was considered. FDG PET/CT images showed intense activity not only in the neck but also in the thorax, abdomen, and pelvis. Biopsy wa...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000267
更新日期:2014-02-01 00:00:00
abstract::Schmorl's node (SN) is a common entity characterized by protrusion of intervertebral disc material through a break in the subchondral end plate of a vertebral body. They can show increased 99mTC methylene diphosphonate uptake on bone scintigraphy mimicking metastasis and can be symptomatic. Differentiation of SN from ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31824d2516
更新日期:2012-07-01 00:00:00
abstract::A 75-year-old woman with a history of sarcoidosis presenting with low cardiac output and complete right bundle-branch block underwent 4'-[methyl-C]-thiothymidine (4DST) PET/CT after cardiac MRI and FDG PET/CT for the evaluation of suspected cardiac sarcoidosis (CS) before treatment. Cardiac MRI revealed late gadoliniu...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002059
更新日期:2018-06-01 00:00:00
abstract::Lower neck uptake in bone scan is hard to interpret because of superposition of several structures. Single photon emission computerized tomography can be beneficial, as illustrated in this patient with a laryngeal tumor. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198312000-00012
更新日期:1983-12-01 00:00:00
abstract:PURPOSE:PET is a useful tool for detecting the presence and extent of brain tau accumulation. However, most first-generation tau PET tracers are limited for high off-target binding and detection of tau in non-Alzheimer disease (AD). This study evaluated potential clinical applications of F-PI-2620 as a novel PET tracer...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003261
更新日期:2020-11-01 00:00:00
abstract::Eleven patients, each with a painful solitary cold nodule of the thyroid were evaluated. All patients had subacute thyroiditis associated with neck pain and tenderness. Despite elevated sedimentation rate and increased thyroglobulin levels, nine of the patients were euthyroid, and I-131 uptake was normal in six. In al...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199511000-00008
更新日期:1995-11-01 00:00:00
abstract::The unique information provided by radionuclide techniques allows the noninvasive characterization of primary tumors and tumor-like conditions of the liver. A thorough knowledge of the mechanisms of radiopharmaceutical localization and the histologic abnormalities present in each condition is required to optimally use...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198707000-00022
更新日期:1987-07-01 00:00:00
abstract::The authors have previously shown that the definition of ablation of thyroid tissue in patients treated with thyroidectomy and radioiodine (I-131) for thyroid carcinoma depends upon the dose of I-131 used to scan the patient. The therapeutic response to I-131 therapy was evaluated in a group of ten differentiated thyr...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198510000-00003
更新日期:1985-10-01 00:00:00