Remission of bone metastases after combined chemotherapy and radionuclide therapy with Re-186 HEDP.

Abstract:

:A patient with disseminated osseous metastases due to breast cancer reported multifocal pain. Because of persisting pain after a first cycle of chemotherapy, 1,295 MBq Re-186 HEDP was administered intravenously. Excellent pain relief was observed. Subsequently, the patient received further combined chemotherapy and Re-186 HEDP therapy and remained pain free. Tc-99m MDP bone imaging showed a significant regression of osseous metastases. It may be speculated that the combination of Re-186 HEDP and chemotherapy results in significantly increased palliation of metastatic bone disease.

journal_name

Clin Nucl Med

authors

Palmedo H,Grünwald F,Wagner U,Köhler S,Krebs D,Biersack HJ

doi

10.1097/00003072-199808000-00001

subject

Has Abstract

pub_date

1998-08-01 00:00:00

pages

501-4

issue

8

eissn

0363-9762

issn

1536-0229

journal_volume

23

pub_type

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