Positive iodine-131 6 beta-iodomethyl-19-norcholesterol (NP-59) adrenal images can precede return of adrenocortical function after o,p' DDD treatment.

Abstract:

:A patient with bilateral adrenal hyperplasia, due to the ectopic adrenocorticotrophic hormone (ACTH) syndrome, received a 3-month course of treatment with 1,1 dichloro-2(o-chlorophenyl)-2-(p-chlorophenyl)ethane (o,p' DDD), which caused adrenal hypofunction requiring steroid therapy. Eleven months later, Cushing's syndrome recurred. His CT scan showed a left adrenal gland that was enlarged and a normal-sized right adrenal gland. However, the NP-59 image showed increased uptake by both glands. Venous effluent was sampled from each adrenal vein. The plasma cortisol level from the left gland was 1392 ng/ml, and that from the right gland was 667 ng/ml. The latter value was not significantly different from the values obtained at peripheral sites (517-744 ng/ml). In the course of recovery from o,p' DDD damage, the ability of the adrenal gland to take up NP-59 may be restored before the return of its biosynthetic and secretory functions. Serial NP-59 adrenal images can anticipate the recurrence of Cushing's syndrome after adrenolytic therapy, thereby permitting early retreatment.

journal_name

Clin Nucl Med

authors

Sparagana M,Ackerman L

doi

10.1097/00003072-198805000-00011

subject

Has Abstract

pub_date

1988-05-01 00:00:00

pages

348-51

issue

5

eissn

0363-9762

issn

1536-0229

journal_volume

13

pub_type

杂志文章
  • Rapidly Growing Chest Wall Mass in a Case of Sporadic Metastatic Paraganglioma: Imaging With 4 Different PET Radiopharmaceuticals.

    abstract::Pheochromocytomas/paragangliomas (PGLs) are rare tumors and mostly benign. We report on a 32-year-old woman with metastatic PGL who was first diagnosed with an abdominal PGL at the age of 12 years. She soon developed metastatic disease and received several treatments including external beam radiation and chemotherapy....

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001116

    authors: Janssen I,Xekouki P,Nambuba J,Chen CC,Herscovitch P,Millo CM,Schrump DS,Pacak K

    更新日期:2016-05-01 00:00:00

  • Ureteral Metastasis From Prostate Cancer: A PSMA PET Pitfall.

    abstract::A 72-year-old man with a history of prostate adenocarcinoma initially managed by radical prostatectomy and salvage radiation therapy underwent resection of a left vas deferens recurrence identified on PSMA PET. Despite an initial response, PSA failed to fall below 3.5 ng/L, prompting re-evaluation with PSMA PET/CT: a ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000003136

    authors: Chaussé G,Skinnider B,Crook J,Black P,Abikhzer G,Probst S

    更新日期:2020-09-01 00:00:00

  • Parathyroid adenomas and hyperplasia. Dual radionuclide scintigraphy and bone densitometry studies.

    abstract::Dual radionuclide imaging of the neck (Tc-99m pertechnetate and TI-201 thallous chloride) was performed in 22 patients with chemical evidence of hyperparathyroidism (elevated blood calcium and parathormone [PTH] levels). Of these, 19 of 22 had localization of a TI-201 "excess" area on radiothallium-radiotechnetium sub...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198504000-00003

    authors: Gupta SM,Belsky JL,Spencer RP,Frias J,Kotch P,Halpin T,Herrera NE

    更新日期:1985-04-01 00:00:00

  • Esthesioneuroblastoma on 68Ga DOTANOC PET/CT.

    abstract::Esthesioneuroblastoma is a rare neoplasm arising from the neural crest cells of olfactory epithelium mostly in the nasal vault. We describe the Ga DOTANOC PET/CT findings of a 44-year-old woman who was operated for right nasal mass diagnosed as paraganglioma in the past and then develop a mass in the right nasal cavit...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002644

    authors: Tripathy S,Kumar R,Kakkar A,Kumar R,Sharma P,Shamim SA

    更新日期:2019-08-01 00:00:00

  • Resolution of Hypoxic Tissue in Cerebellar Hemispheres After Arterial Bypass Surgery in a Patient With Symptomatic Bilateral Vertebral Artery Occlusion: A 18F-FRP170 PET Study.

    abstract::A 48-year-old man experienced recurrent vertigo refractory to antiplatelet medications. Cerebral angiography showed occlusion of bilateral vertebral arteries with poor collateral circulation. PET using O2 gas showed reduced blood flow and metabolic rate of oxygen and elevated oxygen extraction fraction in bilateral ce...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002469

    authors: Oikawa K,Kobayashi M,Beppu T,Terasaki K,Ogasawara K

    更新日期:2019-04-01 00:00:00

  • Pseudo-vascular tumor in a renal flow study.

    abstract::A case in which, for the first time, the superior mesenteric artery caused an appearance mimicking vascular tumor on a kidney radionuclide angiogram (RNA) obtained posteriorly, is reported. A subsequent contrast arteriogram showed that the superior mesenteric artery caused that appearance and confusion with possible v...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198503000-00019

    authors: Elgazzar AH,Fernandez-Ulloa M,Powers GT

    更新日期:1985-03-01 00:00:00

  • Detection of active bleeding from ruptured aortic aneurysm by emergency radionuclide angiography.

    abstract::Radionuclide angiography of the abdominal aorta provides hemodynamic information of the kidneys, aorta and aneurysm as well as the location and extent of aneurysm. Visualization of early abnormal activity in the pelvic region simultaneously with iliac artery visualization is thought to be a specific finding of active ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197807000-00003

    authors: Bunko H,Seto H,Tonami N,Hisada K

    更新日期:1978-07-01 00:00:00

  • The value of urine creatinine analysis in the evaluation on Schilling tests.

    abstract::We performed a prospective study to assess the clinical value of evaluating the adequacy of 24-hour urine specimens submitted for Schilling tests. A total of 121 specimens were evaluated of which 51 had abnormal vitamin B12 excretion values. Of those 51, there were 23 with apparently inadequate total creatinine conten...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199003000-00010

    authors: Heironimus JD,Borchert RD,Weiland FL

    更新日期:1990-03-01 00:00:00

  • Eye Symptoms in a Patient With Prostate Cancer.

    abstract::A 66-year-old man with castration-resistant prostate cancer was evaluated with F-prostate-specific membrane antigen (PSMA) 1007 PET/CT, which revealed extensive PSMA-positive skeletal metastases in the skull, thorax, spine, pelvis, and extremities. He was then treated Lu-PSMA-617 therapy. Twenty-four-hour SPECT/CT rev...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002982

    authors: Kairemo K,Kangasmäki A,Joensuu T,Seregard S

    更新日期:2020-05-01 00:00:00

  • Cholescintigraphy in gallbladder carcinoma.

    abstract::Findings on cholescintigraphy in gallbladder carcinoma are described in five patients. Four patients presenting with acute cholecystitis had nonvisualization of the gallbladder with normal hepatoenteric transit time. One of these had a large portal mass and two had liver metastasis as additional findings. The fifth pa...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198604000-00013

    authors: Colletti PM,Ralls PW,Siegel ME,Halls JM

    更新日期:1986-04-01 00:00:00

  • The false-positive finding of left pulmonary Kimura disease on 18F-FDG PET/CT.

    abstract::Kimura disease is a chronic inflammatory disorder that occurs mainly in Asians. We present a patient with pulmonary Kimura disease assessed by whole-body 18F-FDG PET/CT examination and proved by pathologic findings. Chest x-ray detected left pulmonary hilum enlargement in a 49-year-old Chinese man. CT showed a soft ti...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3182867d70

    authors: Li D,Li YJ,Zhan FH,Dang CJ

    更新日期:2013-07-01 00:00:00

  • Technetium-99m methoxy isobutyl isonitrile simultaneous evaluation of ventricular function and myocardial perfusion in patients with congenital heart disease.

    abstract::The authors evaluated the clinical applications of Tc-99m methoxy isobutyl isonitrile (MIBI) in the simultaneous assessment of ventricular function and myocardial perfusion in patients with congenital heart disease. Global ventricular function was assessed by first-pass ECG gated study. Myocardial perfusion was evalua...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199401000-00009

    authors: Imbriaco M,Cuocolo A,Pace L,Nicolai E,Nappi A,Celentano L,Palma G,Vosa C

    更新日期:1994-01-01 00:00:00

  • Reflux in native kidneys mimicking urine leak postrenal transplant.

    abstract::A 19-year man underwent live related renal transplantation for end-stage renal disease. He was referred for a baseline renal scan on day 4. The urine output was satisfactory and the serum creatinine showed a decreasing trend. Renal dynamic scintigraphy with technetium-99m ethylenedicysteine demonstrated radiotracer ac...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/01.rlu.0000159684.38607.e3

    authors: Tripathi M,Chandrashekar N,Kumar R,Malhotra A

    更新日期:2005-05-01 00:00:00

  • Peliosis Hepatis Simulating Metastatic Liver Disease on FDG PET/CT.

    abstract::A 20-year-old man with gastrointestinal symptoms and weight loss underwent FDG PET/CT, which revealed multiple hypermetabolic hepatic lesions concerning for metastatic liver disease. The outcome of liver biopsy was consistent with the diagnosis of peliosis hepatis which is a rare benign disease characterized by multip...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002114

    authors: Levin D,Hod N,Anconina R,Ezroh Kazap D,Shaco-Levy R,Lantsberg S

    更新日期:2018-07-01 00:00:00

  • Misleading findings on indium-111 leukocyte images.

    abstract::In-111 leukocyte imaging usually yields images which are interpreted easily. Five potentially misleading cases were noted, however, of over 200 scans performed over a four-year period. These included two cases of bladder visualization without bladder inflammation and three cases of abdominal activity without intra-abd...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198606000-00004

    authors: Goodgold HM,Samuels LD

    更新日期:1986-06-01 00:00:00

  • Intense Uptake in Amyloidosis of the Seminal Vesicles on 68Ga-PSMA PET Mimicking Locally Advanced Prostate Cancer.

    abstract::We report a case of benign senile seminal vesicle amyloidosis demonstrating intense Ga-prostate-specific membrane antigen (PSMA) uptake on PET/CT. A 68-year-old man underwent staging PSMA PET/CT and MRI for biopsy-proven prostate adenocarcinoma. There was an intense focus of Ga-PSMA uptake in the primary malignancy, a...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001460

    authors: Stephens M,Kim DI,Shepherd B,Gustafson S,Thomas P

    更新日期:2017-02-01 00:00:00

  • An unusual white blood cell scan in a child with inflammatory bowel disease: a case report.

    abstract::Technetium-99m-labeled leukocyte (WBC) imaging is a valuable screening method for inflammatory bowel disease, especially in children, because of its high rate of sensitivity, low cost, and ease of preparation. A 14-year-old girl is described who had juvenile arthritis and iritis complicated by inflammatory bowel disea...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-200010000-00010

    authors: Porn U,Howman-Giles R,O'Loughlin E,Uren R,Chaitow J

    更新日期:2000-10-01 00:00:00

  • Radionuclide imaging and echography of thyroid nodules.

    abstract::The usefulness of grey scale ultrasonography in association with radionuclide imaging in the evaluation of thyroid nodules is discussed. Nodules were classified in five categories, according to the magnitude of the internal echoes (echogenicity). The assessment of neoplasms in each of these categories is reported in 1...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197907000-00001

    authors: Espinasse P,Espinasse D

    更新日期:1979-07-01 00:00:00

  • Characterization of an orbital melanoma and mucosa associated lymphoid tissue (MALT) lymphoma by dual phase N-isopropyl-p-I-123 iodoamphetamine.

    abstract::Usefulness of N-isopropyl-p-I-123 iodoamphetamine (I-123 IMP) for the detection of malignant melanoma and malignant lymphoma is well known. The appropriate interval from administration until image acquisition is unusual because the accumulation mechanism is different. We present a case of choroidal melanoma of the rig...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3180a1abbd

    authors: Yoshimura M,Akata S,Saito K,Shindo H,Park J,Hirose H,Koizumi K,Goto H

    更新日期:2007-08-01 00:00:00

  • Radionuclide study of functional resolution of unilateral renal vein thrombosis.

    abstract::The diagnosis of unilateral renal vein thrombosis was established in a 50-year-old woman. A functional evaluation, by means of Tc-99m DTPA, was performed almost immediately, and at intervals up to nearly eight months later. Functional return of the involved kidney could be documented by plotting the ratio of affected ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198311000-00007

    authors: Chapman CN,Sziklas JJ,Spencer RP,Rosenberg RJ

    更新日期:1983-11-01 00:00:00

  • Epstein-Barr Virus-negative posttransplant lymphoproliferative disorder with coexisting native renal cell carcinoma: PET/CT demonstration.

    abstract::Compared with the general population, solid organ transplant recipients, including renal transplant patients, who are under long-term immunosuppression, present with up to a 120-fold increased risk of developing skin cancer and non-Hodgkin lymphoma. For the renal transplant population with prior long-term dialysis, th...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/01.rlu.0000204461.39404.56

    authors: Nguyen BD,Ram PC,Roarke MC

    更新日期:2006-04-01 00:00:00

  • The last surviving wall.

    abstract::A total of 66 patients with advanced coronary artery disease (CAD) and 36 with dilated cardiomyopathies (DCM) with ejection fractions less than 20% were analyzed retrospectively to establish patterns of wall motion in each of four quadrants on standard left anterior oblique gated radionuclide ventriculograms. In both ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198709000-00017

    authors: Boykin M,Hartshorne MF,Bauman JM,Byrd BF

    更新日期:1987-09-01 00:00:00

  • Significance of solitary spine abnormalities on technetium-99m bone imaging.

    abstract::Solitary abnormalities located within the spine from 75 bone images with Tc-99m MDP were reviewed. For the sake of convenience, patients were grouped in three classes of age: 15-50, 51-65, and 66-90 years. In 67 cases, the diagnosis was apparent from clinical studies, x-ray examinations, or biopsies. In eight cases, n...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198807000-00013

    authors: Thivolle P,Mathieu L,Mathieu P,Raynal M,Bouyoucef SE,Damideaux J,Vignon E,Berger M

    更新日期:1988-07-01 00:00:00

  • CyberKnife radiosurgery planning of a secreting pituitary adenoma performed with ⁶⁸Ga DOTATATE PET and MRI.

    abstract::The images of a patient with acromegaly, who previously underwent operation for pituitary adenoma, were obtained. The MRI scan showed a mass in the right cavernous sinus, with biochemical test results positive for the presence of a hormonally active adenoma. The patient was scheduled for CyberKnife radiotherapy. Radio...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000535

    authors: d'Amico A,Stąpór-Fudzińska M,Tarnawski R

    更新日期:2014-12-01 00:00:00

  • Radionuclide ventriculographic quantitation of left ventricular dimensions. Comparison to echocardiography.

    abstract::Left ventricular internal cavity dimensions (LVID) were determined from radionuclide ventriculographic (RNVG) studies using a spatial calibration algorithm and visually defined edges and were compared to the results from two-dimensional echocardiography. Routine clinical cases were used with no additional views and no...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199108000-00011

    authors: Madanay LD,Cerqueira MD,Jacobson AF,Matsuoka D,Matsuda M,Stratton JR

    更新日期:1991-08-01 00:00:00

  • Exercise-induced muscle uptake of technetium-99m MDP.

    abstract::Intense muscle localization of Tc-99m MDP to upper extremity musculature was noted three days following weight lifting exercises. This phenomenon is due to an unknown mechanism although several causative factors have been suggested. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198705000-00003

    authors: du Cret RP,Boudreau RJ,Block JB,Jensen PR,Loken MK

    更新日期:1987-05-01 00:00:00

  • 18F-FDG and 68Ga-DOTATATE PET/CT in von Hippel-Lindau Disease-Associated Retinal Hemangioblastoma.

    abstract::Retinal hemangioblastomas are highly vascular benign tumors that can be encountered either sporadically or within the von Hippel-Lindau (VHL) syndrome. We report a case of a VHL patient with retinal hemangioblastoma who underwent PET/CT scans using F-FDG and Ga-DOTATATE. The tumor showed low-level F-FDG and increased ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001511

    authors: Papadakis GZ,Millo C,Jassel IS,Bagci U,Sadowski SM,Karantanas AH,Patronas NJ

    更新日期:2017-03-01 00:00:00

  • Glucose Hypermetabolism in Contralateral Basal Ganglia Demonstrated by Serial FDG PET/CT Scans in a Patient With SLE Chorea.

    abstract::We reported a 24-year-old woman who developed a movement disorder of mouth and limbs during systemic lupus erythematosus. Brain MRI did not find any abnormalities. Increased FDG uptake in basal ganglia was found using FDG PET/CT brain scan. The symptoms remitted after therapy and the activities of the original hyperme...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001450

    authors: Niu N,Cui R

    更新日期:2017-01-01 00:00:00

  • Evaluation of response to multikinase inhibitor in metastatic renal cell carcinoma by FDG PET/contrast-enhanced CT.

    abstract:PURPOSE:Multikinase inhibitor (MKI) is a promising drug for treatment of metastatic renal cell carcinoma (mRCC). We explained the usefulness of [¹⁸F]-2-fluoro-2-deoxyglucose positron emission tomography/contrast-enhanced computed tomography (FDG PET/CECT) for mRCC in evaluating the early response to MKI and in predicti...

    journal_title:Clinical nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/RLU.0b013e3181f9ddd9

    authors: Minamimoto R,Nakaigawa N,Tateishi U,Suzuki A,Shizukuishi K,Kishida T,Miura T,Makiyama K,Yao M,Kubota Y,Inoue T

    更新日期:2010-12-01 00:00:00

  • Unusual metastases of thyroid cancer to mediastinal blood vessels.

    abstract::Poorly differentiated thyroid cancer is a rare thyroid cancer, accounts for approximately 5% of all thyroid cancer cases, and is associated with a poor prognosis. It commonly metastasizes to regional lymph nodes, lung, and bones. We present a patient with poorly differentiated thyroid cancer with unusual extensive spr...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000352

    authors: Ma HY,Moadel R,Freeman LM

    更新日期:2015-01-01 00:00:00