Regional ventilation-perfusion mismatch in interstitial pneumonia. Correlation between scintigraphy and CT.

Abstract:

:Interstitial pneumonia is one of the many causes of a scintigraphic ventilation-perfusion (V/Q) mismatch. To evaluate the morphologic features of V/Q mismatched areas in patients with interstitial pneumonia, we correlated the findings on lung scintigraphy using Kr-81m and Tc-99m MAA with CT scan findings. Of 41 patients, 20 (49%) had a high V/Q mismatched areas. All of these areas corresponded to cystic air spaces shown on CT, and most of the showed a honeycomb pattern. Ventilation-perfusion matched defects were seen in 23 patients (56%). The matched defects corresponded to cystic air spaces (honeycomb or bullous changes) or lung attenuation changes of varying degrees on CT. Cystic air spaces with high V/Q mismatch are considered to be normally ventilated. To distinguish mismatched areas of interstitial pneumonia from areas of pulmonary embolism, it may be necessary to compare scintigraphic findings with CT.

journal_name

Clin Nucl Med

authors

Ogawa Y,Ashizawa K,Hashmi R,Takemoto Y,Hayashi K

doi

10.1097/00003072-199703000-00006

subject

Has Abstract

pub_date

1997-03-01 00:00:00

pages

166-71

issue

3

eissn

0363-9762

issn

1536-0229

journal_volume

22

pub_type

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