Abstract:
:In 14 patients with ophthalmoplegia plus Tc-99m hexamethylpropylene amineoxime (HMPAO) brain SPECT imaging was performed. Three patients showed bilateral parieto-occipital hypoperfusions, and two patients had left parietal defects (one with an additional right temporal lesion). Two patients presented with occipital hypoperfusions and one with a distinct hypoperfusion in the medial part of both frontal lobes. Hypoperfusion of the visual cortex might result from permanently decreased input from the degenerated retina. The hypoperfusion in the visual cortex and in other regions alternatively might reflect direct central nervous system (CNS) involvement due to neuronal degeneration or to impaired vascular function caused by morphologically changed mitochondria in smooth muscle and endothelial cells. The data suggest CNS involvement in ophthalmoplegia plus with abnormalities of cerebral blood flow similar to those found in other mitochondrial encephalomyopathies.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Grünwald F,Zierz S,Broich K,Dewes W,Böker T,Biersack HJdoi
10.1097/00003072-199101000-00005subject
Has Abstractpub_date
1991-01-01 00:00:00pages
20-3issue
1eissn
0363-9762issn
1536-0229journal_volume
16pub_type
杂志文章abstract::A 52-year-old man with metastatic poorly differentiated bronchogenic carcinoma and serum calcium levels as high as 14.6 had intense Tc-99m MDP uptake found throughout the stomach wall on SPECT imaging. FDG uptake assessed by PET imaging was not elevated in the stomach, whereas multiple hyper-metabolic tumor foci could...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199509000-00002
更新日期:1995-09-01 00:00:00
abstract::Stress fractures of the upper extremities are uncommon but can be a serious source of morbidity if not correctly diagnosed. We present a rare case of a 49-year-old female typist, who reported a 4-month history of a pain located in the region of the left lower ulnar epiphysis and extended to the left portion of the wri...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000178030.55730.2e
更新日期:2005-10-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the diagnostic capacity of F-18 fluorodeoxyglucose dual-time-point (DTP) positron emission tomography (PET)/computed tomography (CT) for intrathoracic lymph node (LN) metastases in patients with nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS:Thirty-four patients ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31819a1f3d
更新日期:2009-04-01 00:00:00
abstract::A case of Takayasu's arteritis is reported. Ventilation-perfusion lung scans and exercise thallium scintigraphy clearly showed pulmonary and coronary arterial involvement, respectively. Clinical examination and angiography revealed no other abnormal vascular findings. This case points out the difficulty in attempting ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199302000-00009
更新日期:1993-02-01 00:00:00
abstract::Extraosseous Tc-MDP uptake on bone scans is frequently encountered and has a broad differential diagnosis. A small subset of such patients can present with intestinal Tc-MDP uptake. We present the case of a 35-year-old woman with status after right nephrectomy for renal cell carcinoma, being followed with bone scan fo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002506
更新日期:2019-05-01 00:00:00
abstract::Two patients with myocardial sarcoidosis are presented, both of whom underwent SPECT imaging with Tl-201 and Ga-67. The first had Ga-67 myocardial uptake with a Tl-201 defect, which disappeared with corticosteroid therapy. The second had multiple Tl-201 defects without Ga-67 uptake, which persisted despite corticoster...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199006000-00009
更新日期:1990-06-01 00:00:00
abstract:PURPOSE:Recent studies have shown that thyroglobulin (Tg) concentration is a useful tumor marker in follow-up of differentiated thyroid cancer (DTC) patients after thyroidectomy and subsequent radioiodine (I-131) therapy. However, its role is controversial after total or near-total thyroidectomy before the first I-131 ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182291c65
更新日期:2011-12-01 00:00:00
abstract:INTRODUCTION:The purpose of presurgical assessment is to delimit the epileptogenic zone and the functional deficit zone with a brain MRI, an electroencephalograph or even a stereo-electroencephalograph (SEEG), neuropsychological evaluation, and a cerebral FDG PET. Several studies concur that the hypometabolism of FDG P...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002615
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:This study was performed to evaluate the diagnostic accuracy of brain perfusion SPECT in patients visiting the cognitive disorder clinic for initial evaluation using 3D-SSP compared with using standard transaxial section. MATERIALS AND METHODS:Standard transaxial section displays and 3D-SSP z-score maps obtain...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.rlu.0000246818.24566.54
更新日期:2006-12-01 00:00:00
abstract::E-mail messages and face-to-face meetings both are important methods of communication, and each has its own advantages and disadvantages. Conducting informal one-on-one meetings well is important to the success of a leader or manager. However, the follower can also do many things to optimize the success of a one-on-on...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31824fbc71
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:To establish camera-based methods for estimating Tc-99m mercaptoacetyltriglycine (MAG3) clearance without blood sampling. MATERIALS AND METHODS:The results of renal scintigraphy with Tc-99m MAG3 obtained from 160 patients were analyzed retrospectively. Eight renogram parameters were calculated for each patient...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31821a2a96
更新日期:2011-11-01 00:00:00
abstract::In the course of a work-up for fever of unknown origin associated with intermittent arrhythmias, a gallium scan was performed which revealed diffuse myocardial uptake. The diagnosis of Lyme disease myocarditis subsequently was confirmed by serologic titers. One month following recovery from the acute illness, the abno...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198509000-00002
更新日期:1985-09-01 00:00:00
abstract::In this article, the authors described a 31-year-old woman with differentiated thyroid cancer is presented who had radioiodine uptake in the distribution of the tracheobronchial tree in association with symptoms of an acute respiratory tract infection. As expected, the uptake was transient and disappeared on the follo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199705000-00006
更新日期:1997-05-01 00:00:00
abstract::A 38-year-old man underwent a resection of the left lobe of the liver resection for a solitary hepatic epithelioid hemangioendothelioma. F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) was performed for surveillance. This demonstrated 2 foci of FDG uptake in the liver. These were ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31815969bc
更新日期:2007-12-01 00:00:00
abstract::Carcinoid is a subtype of neuroendocrine tumor, a rare group of tumors that are known to express somatostatin receptor 2. Ga-DOTATATE is a somatostatin analog that is specific for somatostatin receptor 2 and therefore allows visualization of neuroendocrine tumors. We present 2 cases of primary multifocal small bowel c...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002487
更新日期:2019-04-01 00:00:00
abstract::The authors present a case that demonstrates the continued high sensitivity of Tc-99m SC liver-spleen imaging for thoracic splenosis. A patient with profound weight loss, positive PPD and left upper lobe lung density on a chest radiograph was felt to have a strong clinical suspicion of a malignant pulmonary lesion. Tw...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199405000-00014
更新日期:1994-05-01 00:00:00
abstract:PURPOSE:Right bundle branch block (RBBB) is a conduction defect that often is accompanied by nonspecific patient symptoms. The objective of this study was to evaluate the false-positive results obtained with TI-201 myocardial SPECT in patients with RBBB. METHODS:Thirty-one patients (24 men, 7 women; age range, 35 to 7...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200008000-00002
更新日期:2000-08-01 00:00:00
abstract:PURPOSE:We performed a systematic review and meta-analysis on the prognostic value of metabolic tumor volume (MTV) and total lesion glycolysis (TLG) derived from pretreatment F-FDG PET/CT in patients with esophageal cancer. METHODS:PubMed and EMBASE databases were searched until April 12, 2018, for studies that evalua...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,meta分析
doi:10.1097/RLU.0000000000002291
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:Standardized added metabolic (SAM) activity is a functional objective measurement of the total tumoral metabolic activity that avoids partial volume effect and thresholding, which limit conventional PET parameters. The purpose of this study is to investigate the role of SAM in predicting survival in unresectabl...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000991
更新日期:2016-02-01 00:00:00
abstract::The authors report the case of a 27-year-old woman with gamma probe-guided resection of a recurrent regional lymph node metastasis in papillary thyroid cancer. Reoperation is often impaired in cases with extensive scarring because of previous surgery, high-dose radioiodine therapy, and external irradiation. In this ca...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199709000-00002
更新日期:1997-09-01 00:00:00
abstract::This case report describes an I-131 whole-body scan with false-positive uptake at the site of a nose ring in a patient with follicular thyroid cancer. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199510000-00003
更新日期:1995-10-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine the diagnostic value of the combination of F-18 fluorodeoxyglucose (FDG) PET and Tc-99m pertechnetate salivary gland scintigraphy in parotid tumors. MATERIALS AND METHODS:Seventy-two patients with benign parotid gland tumors (n = 52), malignant parotid tumors (n = 12), ...
journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/00003072-200503000-00005
更新日期:2005-03-01 00:00:00
abstract::Captopril renal scintigraphy is a well-known noninvasive tool in the diagnosis of renovascular hypertension. The authors present a case of a patient with malignant hypertension whose captopril renal scintigraphy suggested bilateral and equal renovascular hypertension. His renal angiogram, however, demonstrated no rena...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199204000-00009
更新日期:1992-04-01 00:00:00
abstract:PURPOSE:Fully automated synthesis of 11C-labeled 2β-carbomethoxy-3β-(4-fluorophenyl)tropane (11C CFT) as a dopamine transporter positron emission tomography (PET) tracer is performed with Sep-Pak purification, which cannot separate 11C CFT from nor-β-CFT and will result in the residual precursor nor-β-CFT in the final ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/RLU.0b013e31824c5fae
更新日期:2012-08-01 00:00:00
abstract::A case is presented in which bone imaging over a period of 1 year indicated continued and increased radionuclide uptake. In association with CT and magnetic resonance imaging studies it was determined that the continued increased activity was related to developing bone marrow metastases. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198908000-00009
更新日期:1989-08-01 00:00:00
abstract::A 68-year-old man with sarcoidosis showed high F-FDG uptake in the mediastinal and hilar lymph nodes on F-FDG PET, suggesting active inflammation. F-fluoro-boronophenylalanine (FBPA) PET showed no significant uptake in the mediastinal and hilar lymph nodes, suggesting its cancer specificity as a substrate of L-type am...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003274
更新日期:2020-11-01 00:00:00
abstract::We report the case of a 28-year-old woman presenting behavior disorders of subacute onset. She was referred in our institution for a suspicion of limbic encephalitis. F-FDG PET/CT did not show any mesiotemporal abnormality but depicted a decreased uptake of bilateral parietal and occipital lobes. This atypical pattern...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002098
更新日期:2018-07-01 00:00:00
abstract::Hepatic cavernous hemangiomas rarely grow. Although a few cases have been reported in the literature, none used Tc-99m red blood cell scintigraphy. The authors describe such a case here. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200007000-00003
更新日期:2000-07-01 00:00:00
abstract::A 58-year-old man was referred for selective internal radiation therapy for locally advanced unresectable hepatocellular carcinoma. Intra-arterial particle perfusion scintigraphy was performed with SPECT/CT following intra-arterial injection of Tc macroaggregated albumin. Angiography demonstrated a hepatic falciform a...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001907
更新日期:2018-01-01 00:00:00
abstract::Thallium-201 uptake patterns in the orbits are not widely known. Diffuse, bilateral orbital localization of TI-201 chloride may be an incidental finding because of orbital muscle or other soft tissue uptake. Differences in orbital blood flow and soft tissue mass may be the cause of the varying uptake intensities in mo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199506000-00015
更新日期:1995-06-01 00:00:00