18F-fluorothymidine PET is a potential predictive imaging biomarker of the response to gemcitabine-based chemotherapeutic treatment for recurrent ovarian cancer: preliminary results in three patients.

Abstract:

:In order to establish early and precise methods for evaluating the effect of secondary chemotherapy in patients with recurrent ovarian cancer, both the clinical course of 3 women treated with gemcitabine-based secondary chemotherapy and the potential for early and accurate evaluation of the secondary chemotherapeutic effect of 18F-fluorothymidine (FLT) PET are reported. Standard uptake value with FLT PET decreased earlier than with 18F-fluorodeoxyglucose PET and was better correlated with a reduction in size as measured by CT. FLT PET could become a new standard for monitoring response to gemcitabine-based secondary chemotherapy treatment for recurrent ovarian cancer.

journal_name

Clin Nucl Med

authors

Tsuyoshi H,Morishita F,Orisaka M,Okazawa H,Yoshida Y

doi

10.1097/RLU.0b013e318292ee9c

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

560-3

issue

7

eissn

0363-9762

issn

1536-0229

journal_volume

38

pub_type

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