68Ga-PSMA-Ligand PET/CT Uptake in Anthracosilicosis.

Abstract:

:This interesting image illustrates a case of biopsy-proven pulmonary anthracosilicosis, a mixed dust pneumoconiosis, associated with Ga-PSMA-ligand uptake. Prostate-specific membrane antigen (PSMA) is an emerging imaging biomarker, with clinical application in evaluation of prostate cancer using Ga-PSMA-ligand PET/CT. Contrary to its name, PSMA is expressed in a number of other normal tissues and pathological states. Prostate-specific membrane antigen expression has been linked to tumor angiogenesis in various other epithelial neoplasms, as well as neovasculature associated with tissue regeneration and repair. Awareness of nonneoplastic inflammatory conditions associated with Ga-PSMA-ligand uptake aids in patient assessment and management.

journal_name

Clin Nucl Med

authors

McGuiness M,Sounness B

doi

10.1097/RLU.0000000000001782

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

e431-e432

issue

10

eissn

0363-9762

issn

1536-0229

journal_volume

42

pub_type

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