Fibrous Dysplasia Mimicking Malignancy on 68Ga-DOTATATE PET/CT.

Abstract:

:Fibrous dysplasia of the bone is a developmental benign skeletal disorder characterized by replacement of normal bone and normal bone marrow with abnormal fibro-osseous tissue. We report on a case of a biopsy-proven fibrous dysplasia lesion in the left temporal bone, with intensely increased activity (SUVmax, 56.7) on Ga-DOTATATE PET/CT. The presented data indicate cell surface overexpression of somatostatin receptors by fibrous dysplastic cells and highlight the need of cautious management of Ga-DOTATATE-avid bone lesions, which could mimic malignancy especially in patients with history of neuroendocrine tumors.

journal_name

Clin Nucl Med

authors

Papadakis GZ,Millo C,Sadowski SM,Karantanas AH,Bagci U,Patronas NJ

doi

10.1097/RLU.0000000000001527

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

209-210

issue

3

eissn

0363-9762

issn

1536-0229

journal_volume

42

pub_type

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