Peripheral bone involvement of intravascular large B-cell lymphoma on 99mTc-MDP bone scan and 18F-FDG PET/CT.

Abstract:

:A 64-year-old man was admitted for evaluation of recently developed anemia and bone pain. The bone scan showed diffusely active lesions in the peripheral bones, symmetrically. Interestingly, 18F-FDG PET/CT revealed the hypermetabolic changes in the peripheral bones as well as the internal organs. Biopsy of bone marrow confirmed the diagnosis of intravascular B-cell lymphoma. After the 3 cycles of R-CHOP chemotherapy, 18F-FDG PET/CT showed improvement of the previous hypermetabolic lesions, suggesting good response. Intravascular B-cell lymphoma is a rare and aggressive variant of diffuse large cell lymphoma characterized by proliferation of malignant cells within the vascular lumina.

journal_name

Clin Nucl Med

authors

Oh SY,Cheon GJ,Jeong E,Lee S,Park TG,Pahk K,Choe JG

doi

10.1097/RLU.0b013e31825ae70e

subject

Has Abstract

pub_date

2012-08-01 00:00:00

pages

810-1

issue

8

eissn

0363-9762

issn

1536-0229

pii

00003072-201208000-00025

journal_volume

37

pub_type

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