Transient false-positive hepatobiliary scan associated with ceftriaxone therapy.

Abstract:

:Drug related false-positive hepatobiliary imaging is uncommon. The authors present a case of a 54-year-old woman who was treated with intravenous ceftriaxone for bacterial meningitis. Symptoms of acute cholecystitis subsequently developed and a sonogram revealed a gallstone. A Tc-99m DISIDA hepatobiliary study was positive for cystic duct obstruction. After discontinuation of ceftriaxone, the patient's clinical condition improved and, 2 weeks later, a repeat hepatobiliary scan was normal. High doses of ceftriaxone and prolonged administration may lead to formation of pseudocholelithiasis and signs of acute cholecystitis. Although this condition is usually benign and reversible, discontinuation of the drug is warranted when symptoms of acute cholecystitis are accompanied by a positive hepatobiliary scan.

journal_name

Clin Nucl Med

authors

Lorberboym M,Machado M,Glajchen N,Pertsemlidis D

doi

10.1097/00003072-199601000-00002

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

4-7

issue

1

eissn

0363-9762

issn

1536-0229

journal_volume

21

pub_type

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