Abstract:
:Plummer's disease (autonomous goiter) presents a spectrum of forms, raging from solitary autonomous thyroid nodules to numerous small autonomous areas, and from unequivocal to servere hyperthyroidism. Progression is often very slow, but data on long-term follow up are scare, contradictory and limited to solitary nodules. We re-examined 58 untreated patients on one or more occasions. Follow-up time ranged from 1 to 12 years (average 4 years). There were gross clinical or scintigraphic changes in 13 patients. Three included six euthyroidal patients who became (mildly) hyperthyroid, one with a change from single to numerous "hot spots," and one in which the radionuclide disappeared in one of two separate autonomous areas. Minor changes were seen in 14 patients. Changes occurred irrespective of the scintigraphic pattern. In contrast, progression was very rapid in two of 300 other patients with the disease, leading to fatal thyrotoxic crisis withing three months in one. In another patient, transient hyperthyroidism was documented after excessive iodine administration. It is concluded that patients may be left untreated as long as serious complaints and clinical suspicion of associated malignancy are absent.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Wiener JD,de Vries AAdoi
10.1097/00003072-197905000-00002subject
Has Abstractpub_date
1979-05-01 00:00:00pages
181-90issue
5eissn
0363-9762issn
1536-0229journal_volume
4pub_type
杂志文章abstract::Acute suppurative thyroiditis is an uncommon condition. Most patients have preexisting oropharyngeal fistulae. Penetrating oropharyngeal injuries resulting from swallowed foreign bodies provide an acquired channel of infection spreading into the relatively resistant thyroid gland. The authors describe a patient with i...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200004000-00001
更新日期:2000-04-01 00:00:00
abstract::Ga somatostatin receptor PET/CT, currently the most sensitive imaging modality for well-differentiated neuroendocrine tumors, is based on the molecular imaging of somatostatin receptors (SSTRs) that are expressed in different tumor entities such as neuroendocrine neoplasms, lymphomas, meningiomas, or renal cell cancer...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000351
更新日期:2014-08-01 00:00:00
abstract::A 23-year-old man with Dyke-Davidoff-Masson syndrome (DDMS) was admitted to the hospital with increasing frequency of epileptic seizures. Physical examination revealed mental retardation, left facial asymmetry, and left-sided spastic hemiparesis. Dysdiadochokinesia on the left upper limb was detected, and there was no...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000890
更新日期:2015-09-01 00:00:00
abstract::A 28-year-old woman with a history of prior bilateral retinoblastoma presented with general fatigue, anemia, and a urinary bladder mass seen on abdominal ultrasound and CT. She was referred for a staging 18F-FDG PET/CT, which showed an intensely FDG-avid bladder mass that was biopsied to reveal a leiomyosarcoma, with ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182523e33
更新日期:2013-05-01 00:00:00
abstract::Bone, brain, and gallium scintigrams are presented of a 48-year-old man with biopsy-proven cerebral amyloidosis. Brain scintigraphy revealed a well-circumscribed accumulation of Tc-99m pertechnetate in the amyloidoma. Bone scintigraphy using Tc-99m methylenediphosphonate likewise exhibited increased activity in the sa...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198311000-00003
更新日期:1983-11-01 00:00:00
abstract::This is the first report in the nuclear medicine literature of the scintigraphic appearance of the piriformis muscle syndrome. This syndrome previously has been thought to be a purely clinical diagnosis and imaging modalities have been ignored. However, its confusing clinical presentation can lead to unnecessary surgi...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198505000-00011
更新日期:1985-05-01 00:00:00
abstract::We emphasize the role of Tc-99m-3,3-diphosphono-1,2-propanodicarboxylicacid (DPD) scintigraphy as a noninvasive tool to distinguish transthyretin (TTR)-related cardiac amyloidosis from other forms of cardiac amyloidosis. We report the case of a 76-year-old male patient suffering from congestive heart failure in whom i...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318248512c
更新日期:2012-08-01 00:00:00
abstract::We report incidental FDG PET/CT findings of deep venous thrombosis and pulmonary embolism in a patient with bacteremia. In this patient, diagnosis of thromboembolism was not considered until FDG PET/CT imaging was performed, and the findings prompted immediate anticoagulant therapy. The role of FDG PET/CT in venous th...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182817aaf
更新日期:2013-04-01 00:00:00
abstract::Hypophosphatemic osteomalacia, a familial or rarely acquired disorder, is characterized biochemically by hypophosphatemia, decreased renal tubular reabsorption of phosphate, decreased intestinal absorption of calcium, and normal serum calcium. This report concerns a rare case of hypophosphatemic osteomalacia of unknow...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200005000-00003
更新日期:2000-05-01 00:00:00
abstract:PURPOSE:This pilot study aimed to prove the complementary value of a novel Gallium-labeled heterodimeric peptide, Ga-NOTA-3P-TATE-RGD, in detection and evaluation of tumors with somatostatin receptor subtype 2 or integrin αvβ3 overexpression, including non-small cell lung cancer (NSCLC), small-cell lung cancer (SCLC), ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002680
更新日期:2019-09-01 00:00:00
abstract::Biliary scans of 84 hospitalized patients believed to likely have acute cholecystitis, including 55 scans that had a radionuclide angiography phase, were retrospectively evaluated to determine the frequency of the rim sign and hyperperfusion, and to test the hypothesis that more intense hyperperfusion or rim sign is a...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199310000-00009
更新日期:1993-10-01 00:00:00
abstract::A 66-year-old man with castration-resistant prostate cancer was evaluated with F-prostate-specific membrane antigen (PSMA) 1007 PET/CT, which revealed extensive PSMA-positive skeletal metastases in the skull, thorax, spine, pelvis, and extremities. He was then treated Lu-PSMA-617 therapy. Twenty-four-hour SPECT/CT rev...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002982
更新日期:2020-05-01 00:00:00
abstract::Scintigraphy was instrumental in two histologically proven cases of forme fruste melorheostosis. Radionuclide bone scans demonstrated a moderately increased uptake of radiopharmaceutical localized to the "flowing" cortical hyperostosis of melorheostosis observed radiographically. The medullary portion of the affected ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199406000-00009
更新日期:1994-06-01 00:00:00
abstract:PURPOSE:No study has analyzed a sizeable cohort that comprised solely peripheral T-cell lymphoma (PTCL) patients for the diagnostic and prognostic performance of F-FDG PET/CT for bone marrow (BM) involvement. This study aimed to investigate the utility of PET/CT for the identification of BM involvement and to explore i...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002516
更新日期:2019-05-01 00:00:00
abstract::Iodine-123 MIBG is a norepinephrine analog which can be used to image the sympathetic innervation of the heart. The authors report a patient with myotonic dystrophy whose I-123 MIBG SPECT revealed accelerated washout of I-123 MIBG from infero-posterior and a part of lateral wall, although Tl-201 SPECT showed no abnorm...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199411000-00006
更新日期:1994-11-01 00:00:00
abstract:PURPOSE:This study compared the effectiveness of fluorodeoxyglucose (FDG) positron emission tomography (PET) with computed tomography (CT), magnetic resonance imaging (MRI), or both for the assessment of recurrent squamous cell carcinoma of the head and neck. The value of quantifying the standardized uptake values (SUV...
journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/00003072-200102000-00008
更新日期:2001-02-01 00:00:00
abstract::A 20-year-old man with gastrointestinal symptoms and weight loss underwent FDG PET/CT, which revealed multiple hypermetabolic hepatic lesions concerning for metastatic liver disease. The outcome of liver biopsy was consistent with the diagnosis of peliosis hepatis which is a rare benign disease characterized by multip...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002114
更新日期:2018-07-01 00:00:00
abstract::A case in which, for the first time, the superior mesenteric artery caused an appearance mimicking vascular tumor on a kidney radionuclide angiogram (RNA) obtained posteriorly, is reported. A subsequent contrast arteriogram showed that the superior mesenteric artery caused that appearance and confusion with possible v...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198503000-00019
更新日期:1985-03-01 00:00:00
abstract::A case of 99mTcO4 accumulation within the thorax is reported, consistent with septic emboli and thyroiditis during routine thyroid scintigraphy for subclinical hyperthyroidism. After antibiotic treatment, repeated 99mTcO4 imaging revealed complete resolution of foci of septic emboli. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000245
更新日期:2013-12-01 00:00:00
abstract::We present the case of a 61-year-old woman with fever and acute meningitis. Clinical evaluation revealed maculopapular rash, right gluteus cellulitis, and centered retinal hemorrhages. In the intensive care unit, persistent Staphylococcus bacteremia was detected. However, transesophageal echocardiography did not revea...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003301
更新日期:2020-12-01 00:00:00
abstract::Ocular metastases secondary to thyroid cancer are extremely uncommon, typically affecting the orbit rather than the globe and uvea. Within the uveal structures, the choroid is more commonly involved than the iris and ciliary body. We present a 56-year-old male patient who underwent total thyroidectomy for metastatic p...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31827a2275
更新日期:2013-02-01 00:00:00
abstract::After prolonged androgen deprivation therapy, a subset of castrate-resistant prostate cancer patients will develop neuroendocrine prostate cancer (NEPC) associated with resistance to further hormonal therapy and frequent visceral metastases. Imaging the presence of somatostatin receptors on the cancer cell surface may...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000776
更新日期:2015-06-01 00:00:00
abstract::We report two cases of supra-scrotal vasitis incidentally detected in patients who had undergone mesh herniorrhaphy. PET/CT in patients undergoing lymphoma work-up and health check-up revealed hypermetabolic dilatation of vas deferens in the external iliac area. There were no symptoms, and blood test results did not i...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002402
更新日期:2019-02-01 00:00:00
abstract::Captopril renal scintigraphy is a well-known noninvasive tool in the diagnosis of renovascular hypertension. The authors present a case of a patient with malignant hypertension whose captopril renal scintigraphy suggested bilateral and equal renovascular hypertension. His renal angiogram, however, demonstrated no rena...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199204000-00009
更新日期:1992-04-01 00:00:00
abstract:PURPOSE:A 68-year-old man with metastatic follicular thyroid carcinoma had T3 hyperthyroidism. MATERIAL AND METHODS:A bone scan showed intense uptake in the thyroid and multiple areas of increased uptake in the skeleton. Hyperthyroidism persisted after total thyroidectomy. Treatment with I-131 induced a transient stat...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200502000-00001
更新日期:2005-02-01 00:00:00
abstract:PURPOSE:The authors' goal was to determine whether the prevalence of pulmonary embolism in patients with matching ventilation-perfusion (V-Q) defects and chest radiographic opacities differs depending on the degree of perfusion deficit (absent versus decreased). METHODS:The authors performed a retrospective analysis o...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200009000-00002
更新日期:2000-09-01 00:00:00
abstract:PURPOSE:Gliomas constitute the most frequent primary brain tumors. Glioblastoma, the most common and malignant glioma in adults, has dismal prognosis with any current therapy. On the other hand, low-grade gliomas, the second most common type of gliomas, are potentially curative with appropriate treatment. METHODS:We c...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,meta分析
doi:10.1097/RLU.0000000000002654
更新日期:2019-11-01 00:00:00
abstract::Both female adnexal tumor of possible wolffian origin (FATWO) and metastasis to the appendix from any primary tumor are extremely rare entities. The appendiceal metastasis from FATWO has not been reported, and there is a lack of the literature regarding FDG PET/CT study in both. We reported the case of an appendiceal ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318203bc77
更新日期:2011-02-01 00:00:00
abstract::Various etiologies could cause focal I accumulation. Hepatic cyst is one of these etiologies. Here we present a 59-year-old man with a history of papillary thyroid cancer resection who received radioiodine therapy for three times. The images after the I therapy of the second and third time showed variable activity upt...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002442
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:Multikinase inhibitor (MKI) is a promising drug for treatment of metastatic renal cell carcinoma (mRCC). We explained the usefulness of [¹⁸F]-2-fluoro-2-deoxyglucose positron emission tomography/contrast-enhanced computed tomography (FDG PET/CECT) for mRCC in evaluating the early response to MKI and in predicti...
journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/RLU.0b013e3181f9ddd9
更新日期:2010-12-01 00:00:00