Disseminated extranodal NK/T-cell lymphoma, nasal type, with multiple subcutaneous nodules: utility of 18F-FDG PET in staging.

Abstract:

:A 49-year-old man presented with a left nasal cavity mass, biopsy of which revealed extranodal NK/T cell lymphoma. A PET-CT scan showed increased F-18 FDG uptake in the nasal mass, anterior mediastinal lymph nodes, and multiple subcutaneous nodular deposits in the chest wall, gluteal region, and right femoral areas. The patient achieved complete remission with salvage l-asparaginase therapy after failing first-line standard anthracycline-based chemotherapy. PET-CT was very useful in detecting subcutaneous nodules consistent with widespread dissemination. There is limited literature data on the use of the PET scan in the diagnosis and staging of extranodal nasal NK/T-cell lymphomas. Our case highlights the important role of F-18 FDG PET in the staging of these patients.

journal_name

Clin Nucl Med

authors

Berk V,Yildiz R,Akdemir UO,Akyurek N,Karabacak NI,Coskun U,Benekli M

doi

10.1097/RLU.0b013e31816a7a23

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

365-6

issue

5

eissn

0363-9762

issn

1536-0229

pii

00003072-200805000-00020

journal_volume

33

pub_type

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