False-Positive 18F-FDG PET/CT Imaging: Dramatic "Flare Response" After Rituximab Administration.

Abstract:

:We report the case of a 45-year-old woman diagnosed with non-Hodgkin lymphoma. Six months after completion of R-CHOP, she relapsed, and 2 cycles of R-ESHAP were given, with a view to allograft transplant. One month later, F-FDG PET/CT revealed disease progression. Biopsy of lymph nodes showed reactive changes, without evidence of lymphoma. Rituximab, a monoclonal antibody, is used for treatment of non-Hodgkin lymphoma, but its addition may result in an extensive inflammatory response. It is important to be aware of the potential for false-positive F-FDG PET/CT imaging after rituximab therapy. Unexpected findings should be confirmed by biopsy.

journal_name

Clin Nucl Med

authors

Skoura E,Ardeshna K,Halsey R,Wan S,Kayani I

doi

10.1097/RLU.0000000000001083

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

e171-2

issue

3

eissn

0363-9762

issn

1536-0229

journal_volume

41

pub_type

杂志文章
  • Radioiodine bronchogram in acute respiratory tract infection.

    abstract::In this article, the authors described a 31-year-old woman with differentiated thyroid cancer is presented who had radioiodine uptake in the distribution of the tracheobronchial tree in association with symptoms of an acute respiratory tract infection. As expected, the uptake was transient and disappeared on the follo...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199705000-00006

    authors: Bakheet SM,Hammami MM,Powe J

    更新日期:1997-05-01 00:00:00

  • Pseudo-Budd-Chiari syndrome.

    abstract::A patient with clinical, laboratory, radiographic and scintigraphic findings resembling the Budd-Chiari syndrome is described. However, at autopsy there was no thrombotic occlusion of any of the intrahepatic veins. The right hepatic vein was completely constricted by the hypertrophied left lobe of the liver, and the l...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197801000-00009

    authors: Dhawan VM,Sziklas JJ,Spencer RP

    更新日期:1978-01-01 00:00:00

  • Solitary Acute Inflammatory Demyelinating Lesion of the Cervical Spinal Cord Mimicking Malignancy on FDG PET/CT.

    abstract::A 43-year-old woman presented with numbness of the left hand and leg for 4 weeks. MRI of the spinal cord revealed an intramedullary lesion with central nodular enhancement at the C3 level. Primary tumor or metastasis of the cervical spinal cord was suspected. FDG PET/CT showed focal hypermetabolism of the spinal cord ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000003287

    authors: Liu Q,Liu M,Bai Y,Dong A

    更新日期:2020-12-01 00:00:00

  • Ga-67 uptake unsuppressed by leukopenia and intense antibiotic therapy.

    abstract::The authors describe a patient with myelofibrosis who showed intense Ga-67 uptake in spite of being severely leukopenic and receiving large amounts of antibiotics. They conclude that false-negative results associated with leukopenia or intensive antibiotic treatment may not always be correct. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199202000-00004

    authors: Gorenberg M,Groshar D,Even-Sapir E,Ben-Haim S,Israel O,Front D

    更新日期:1992-02-01 00:00:00

  • The last surviving wall.

    abstract::A total of 66 patients with advanced coronary artery disease (CAD) and 36 with dilated cardiomyopathies (DCM) with ejection fractions less than 20% were analyzed retrospectively to establish patterns of wall motion in each of four quadrants on standard left anterior oblique gated radionuclide ventriculograms. In both ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198709000-00017

    authors: Boykin M,Hartshorne MF,Bauman JM,Byrd BF

    更新日期:1987-09-01 00:00:00

  • Quality and Safety in Health Care, Part L: Positive Psychology and Burnout.

    abstract::There are many lessons relevant to burnout from studying the literature on positive psychology. For example, resilience can be taught. A major portion of resilience and fighting burnout is finding meaning in work. Positive thinking, optimism, positive self-talk, and ways to diminish stress and increase happiness and e...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002439

    authors: Harolds JA

    更新日期:2019-08-01 00:00:00

  • Glucose Hypermetabolism in Contralateral Basal Ganglia Demonstrated by Serial FDG PET/CT Scans in a Patient With SLE Chorea.

    abstract::We reported a 24-year-old woman who developed a movement disorder of mouth and limbs during systemic lupus erythematosus. Brain MRI did not find any abnormalities. Increased FDG uptake in basal ganglia was found using FDG PET/CT brain scan. The symptoms remitted after therapy and the activities of the original hyperme...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001450

    authors: Niu N,Cui R

    更新日期:2017-01-01 00:00:00

  • Standardized Added Metabolic Activity Predicts Survival After Intra-arterial Resin-Based 90Y Radioembolization Therapy in Unresectable Chemorefractory Metastatic Colorectal Cancer to the Liver.

    abstract:PURPOSE:Standardized added metabolic (SAM) activity is a functional objective measurement of the total tumoral metabolic activity that avoids partial volume effect and thresholding, which limit conventional PET parameters. The purpose of this study is to investigate the role of SAM in predicting survival in unresectabl...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000991

    authors: Edalat F,Camacho JC,Kokabi N,Kendi AT,Galt JR,Kim HS

    更新日期:2016-02-01 00:00:00

  • Subacute splenic abscess. Appearance on indium-111 leukocyte, gallium-67, and technetium-99m sulfur colloid imaging.

    abstract::A case of a 23-year-old man with an encapsulated, anaerobic splenic abscess is reported. Both the In-111 leukocyte and Tc-99m sulfur colloid scans demonstrated an intrasplenic defect. The Ga-67 citrate scan revealed uptake in the rim of the abscess only where the abscess cavity was relatively photon-deficient. The com...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:

    authors: Ammann W,Chiu BK,Wright JM

    更新日期:1986-03-01 00:00:00

  • FDG PET/CT in Carcinoma of the Tongue With Bilateral Adrenal Metastases.

    abstract::Squamous cell carcinoma is the most common malignant neoplasm of the oral cavity, and it contributes approximately 90% of all oral malignancies. We present a case of a squamous cell carcinoma of the tongue with rare site of bilateral adrenal metastases on F-FDG PET/CT with response evaluation after chemotherapy. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001521

    authors: Agarwal KK,Parida GK,Tripathi M,Sahoo MK,Thakar A,Bal CS,Kumar R

    更新日期:2017-02-01 00:00:00

  • Scintigraphic Identification of Gastric Tissue in a Mediastinal Mass.

    abstract::We present a Tc pertechnetate scintigraphy performed in a 64-year-old woman to investigate a mediastinal cystic mass in search of residual gastric mucosa after gastrectomy. She had a history of esophagectomy and gastric pull-up for esophageal cancer. Postoperative leakage necessitated ablation of the gastric pull-up a...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001078

    authors: Mainta IC,Montet X,Willi JP,Dulguerov P,Rager O

    更新日期:2016-03-01 00:00:00

  • (18)F-FDG PET/CT in an unusual case of cardiac plexiform neurofibromatosis.

    abstract::Cardiac involvement is rare in neurofibromatosis 1 (NF 1). Very few cases of cardiac masses in this entity have been documented in the world literature. We present the F-FDG PET/CT findings in a rare case of cardiac plexiform neurofibromatosis. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000750

    authors: D'souza MM,Sondhi P,D'souza P,Sharma R,Jaimini A,Pandey S,Mondal A,Tripathi RP

    更新日期:2015-06-01 00:00:00

  • A new thrombus imaging agent. Human recombinant fibrin binding domain labeled with In-111.

    abstract::The amino-terminal domain of fibronectin has a fibrin binding site and a site for covalent cross-linking to fibrin. This fibrin binding domain was isolated from human recombinant fibronectin and labeled with In-111; the final molecular weight was 12 kD. It was applied to a pilot study of 62 patients; 30 who were thoug...

    journal_title:Clinical nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/00003072-199505000-00004

    authors: Rosenthall L,Leclerc J

    更新日期:1995-05-01 00:00:00

  • Intense Muscle Activity Due to Polymyositis Incidentally Detected in a Patient Evaluated for Possible Malignancy by FDG PET/CT Imaging.

    abstract::A 42-year-old woman suffered shortness of breath and whole-body pain, more prominent in both thighs. After the initial assessment, a paraneoplastic syndrome was considered clinically, and FDG PET/CT was performed to search culprit malignancy. The images did not reveal any focal lesion typical of solid hypermetabolic m...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001727

    authors: Bai X,Tie N,Wang X,Zhao J

    更新日期:2017-08-01 00:00:00

  • Unexpected pulmonary clumping of In-111 leukocytes attributable to indium oxine reagent.

    abstract::Five cases of artifactual In-111 leukocyte pulmonary activity were noted at three local hospitals in a 4-day period. Based on the differences in the preparation of the final indium leukocyte product, the problem could be attributed to the indium oxine reagent in a specific lot. This artifact of multiple small foci of ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199309000-00008

    authors: Bohdiewicz PJ,Fink-Bennett D,Nagle C,Abghari R,Gutkowski R,Dworkin HJ

    更新日期:1993-09-01 00:00:00

  • Incidental detection of bilateral elastofibroma dorsi with F-18 FDG PET/CT.

    abstract::An 83-year-old asymptomatic woman with a history of breast cancer treated with resection, radiation, and chemotherapy was studied with F-18 FDG positron emission tomography/computed tomography (PET/CT) for staging purposes. The whole-body F-18 FDG PET/CT images revealed poorly circumscribed, bilateral soft tissue mass...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/01.rlu.0000178786.99368.1d

    authors: Wasyliw CW,Caride VJ

    更新日期:2005-10-01 00:00:00

  • On the natural history of Plummer's disease.

    abstract::Plummer's disease (autonomous goiter) presents a spectrum of forms, raging from solitary autonomous thyroid nodules to numerous small autonomous areas, and from unequivocal to servere hyperthyroidism. Progression is often very slow, but data on long-term follow up are scare, contradictory and limited to solitary nodul...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197905000-00002

    authors: Wiener JD,de Vries AA

    更新日期:1979-05-01 00:00:00

  • Discordant uptake of technetium-99m DISIDA and technetium-99m sulfur colloid in an amebic abscess.

    abstract::Hepatobiliary imaging in a patient with an amebic abscess showed an early cold defect that later showed rim enhancement. A Tc-99m SC scan did not show prominent flow (making hepatoma unlikely) and showed the previously noted defect to appear larger and without rim enhancement. The differential damage to Kupffer cells ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198802000-00011

    authors: Allard JC,Lee VW,Foster J

    更新日期:1988-02-01 00:00:00

  • Myocardial infarct imaging with 99mTc-pyrophosphate and 99mTc-methylene diphosphonate: lack of correlation.

    abstract::A prospective study of eight patients with recent transmural myocardial infarction was performed using 99mTc-Sn-pyrophosphate and 99mTc-Sn-methylene diphosphonate in each patient. All pyrophosphate scans were strongly positive whereas the diphosphonate scan was strongly positive in only one case. We conclude that 99mT...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197903000-00001

    authors: Makler PT Jr,Lederman S,Charkes ND,Malmud LS,Warner H,Reilley JJ

    更新日期:1979-03-01 00:00:00

  • Asymmetric abnormality of renal perfusion with symmetric function in aortic dissection.

    abstract::Two cases of aortic dissection are presented in which discordance between renal perfusion and function has been demonstrated with Tc-99m DTPA. Renal perfusion on the affected side was decreased on blood flow imaging, whereas renal function, including parenchymal accumulation and excretion assessed by subsequent sequen...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199201000-00011

    authors: Aburano T,Yokoyama K,Taki J,Takayama T,Shuke N,Tonami N,Hisada K

    更新日期:1992-01-01 00:00:00

  • Positive iodine-131 6 beta-iodomethyl-19-norcholesterol (NP-59) adrenal images can precede return of adrenocortical function after o,p' DDD treatment.

    abstract::A patient with bilateral adrenal hyperplasia, due to the ectopic adrenocorticotrophic hormone (ACTH) syndrome, received a 3-month course of treatment with 1,1 dichloro-2(o-chlorophenyl)-2-(p-chlorophenyl)ethane (o,p' DDD), which caused adrenal hypofunction requiring steroid therapy. Eleven months later, Cushing's synd...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198805000-00011

    authors: Sparagana M,Ackerman L

    更新日期:1988-05-01 00:00:00

  • Predicting Response to Immunotherapy by Evaluating Tumors, Lymphoid Cell-Rich Organs, and Immune-Related Adverse Events Using FDG-PET/CT.

    abstract:PURPOSE:To investigate whether the evaluation of tumors, lymphoid cell-rich organs, and immune-related adverse events (IRAE) with F-FDG PET/CT can predict the efficacy and outcome of immunotherapy. METHODS:Forty patients who underwent F-FDG-PET/CT scans before and after therapy with immune checkpoint inhibitors from D...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002453

    authors: Nobashi T,Baratto L,Reddy SA,Srinivas S,Toriihara A,Hatami N,Yohannan TK,Mittra E

    更新日期:2019-04-01 00:00:00

  • A Rare Case of Primary Endometrial Hepatoid Adenocarcinoma on 18F-FDG PET/CT.

    abstract::Primary endometrial hepatoid adenocarcinoma is a rare tumor. We present a case of a 64-year-old woman with vaginal bleeding for 2 months and a markedly elevated serum α-fetoprotein of 3931 ng/mL. Hysteroscopic segmental curettage revealed endometrial adenocarcinoma. A pelvic MRI was performed for local tumor invasion,...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002538

    authors: Yin H,Hu Y,Xiu Y,Luo R,Shi H

    更新日期:2019-07-01 00:00:00

  • High resolution Tc-99m HMPAO SPECT in a patient with transient global amnesia.

    abstract::This is a report of a patient who underwent high-resolution brain perfusion SPECT studies during and after an episode of transient global amnesia. During the attack, SPECT imaging showed increased perfusion in the left medial temporal region involving the amygdala and hippocampus. After recovery from amnesia, a follow...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199301000-00011

    authors: Matsuda H,Higashi S,Tsuji S,Sumiya H,Miyauchi T,Hisada K,Yamashita J

    更新日期:1993-01-01 00:00:00

  • Accumulation of technetium-99m MDP in a cavernous hemangioma of the liver.

    abstract::A cavernous hemangioma of the liver presented as an area of increased activity on an isotope bone scan. A review of the literature fails to reveal any previous reports of this phenomenon. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198607000-00009

    authors: Burkhalter JL,Morano JU,Patel BR

    更新日期:1986-07-01 00:00:00

  • Immunoscintigraphic localization in a benign thyroid neoplasm of a monoclonal antibody directed against melanoma.

    abstract::In a prospective study for evaluation of the use of a monoclonal antibody directed against melanoma in the staging of patients affected by malignant melanoma, we report monoclonal antibody uptake in a follicular thyroid adenoma. Computed tomography, ultrasonography, and pertechnetate scintigraphy did not provide a cer...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199105000-00010

    authors: Feggi L,Prandini N,Pansini G,Virgili T,Indelli M,Virgili AR

    更新日期:1991-05-01 00:00:00

  • (18)F-FDG PET in the evaluation of acuity of deep vein thrombosis.

    abstract:PURPOSE:F-FDG PET has been used for vascular disease, but its role in deep vein thrombosis (DVT) remains prospectively unexplored. PATIENTS AND METHODS:Whole-body F-FDG PET/CT scans were performed in patients 1 to 10 weeks after onset of symptomatic DVT (n = 12) and in control subjects without DVT (n = 24). The metabo...

    journal_title:Clinical nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/RLU.0b013e3182638934

    authors: Rondina MT,Lam UT,Pendleton RC,Kraiss LW,Wanner N,Zimmerman GA,Hoffman JM,Hanrahan C,Boucher K,Christian PE,Butterfield RI,Morton KA

    更新日期:2012-12-01 00:00:00

  • SPECT evaluation of brain perfusion reserve by the acetazolamide test using Tc-99m HMPAO.

    abstract::This report describes a new approach to the evaluation of brain perfusion reserve using Tc-99m HMPAO SPECT. Consecutive brain Tc-99m HMPAO SPECT studies before and after acetazolamide (Diamox) administration were performed within 30 minutes on 19 patients with significant vascular occlusive lesions. Thirteen patients ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199108000-00008

    authors: Matsuda H,Higashi S,Kinuya K,Tsuji S,Nozaki J,Sumiya H,Hisada K,Yamashita J

    更新日期:1991-08-01 00:00:00

  • FDG PET/CT in detection of adrenal metastasis in patients with renal cell carcinoma.

    abstract:AIM:Adrenal metastasis in renal cell carcinoma (RCC) is uncommon. The present study was aimed to evaluate the role of fluoro-deoxy-glucose positron emission tomography (FDG PET)/computed tomography (CT) in the detection of adrenal metastasis in patients with RCC. MATERIALS AND METHODS:A total of 9 FDG PET/CT scans wer...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3182175435

    authors: Kumar R,Shamim SA,Shandal V,Sharma P,Gadodia A,Malhotra A

    更新日期:2011-07-01 00:00:00

  • (99m)Tc sestamibi as a prognostic factor of response to first-line therapy and outcome in patients with malignant lymphoma.

    abstract:INTRODUCTION:Resistance to chemotherapy poses a major problem in cancer patients. Although of multifactorial origin, some of the implicated mechanisms also interfere with (99m)Tc-MIBI uptake and retention in cancer cells. The aim of the current study was to investigate the prognostic value of baseline (99m)Tc-MIBI imag...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3182a755c8

    authors: Spyridonidis TJ,Matsouka P,Symeonidis A,Savvopoulos C,Vassilakos PJ,Apostolopoulos DJ

    更新日期:2013-11-01 00:00:00