Abstract：
PURPOSE:To evaluate the preliminary results of vaginal-cuff relapses (VCR) and complications of a short brachytherapy (BT) schedule in postoperative endometrial carcinoma. METHODS AND MATERIALS:From September 2011 to December 2014, 102 patients were treated with postoperative BT for endometrial carcinoma. Seventy-four patients received a single 7 Gy dose after external beam irradiation (Group 1), and 28 intermediate-risk patients received three daily fractions of 6 Gy (Group 2). The dose was prescribed at 5 mm from the applicator surface. Toxicity was prospectively evaluated after the objective late effects of normal tissues-subjective, objective, management, analytic scores for vagina and RTOG scores for rectum and bladder. STATISTICS:χ2 and Student's t tests. RESULTS:The mean followup was 28.85 months (9.6-58.5) in Group 1 and 31.19 months (7.7-62.3) in Group 2. No VCR was found during followup. Late toxicity: vagina toxicity was developed in 24.32% of the patients in Group 1 (G1-G2) and in 21.4% in Group 2 (G1-G2 but 1 G3). Rectal toxicity appeared in only 2.7% of patients in Group 1 (G1). Neither Group 1 nor Group 2 presented late bladder toxicity. No differences were found in late toxicity between Groups 1 and 2. CONCLUSIONS:The present short BT schedule was safe in relation to VCR and late toxicity for the followup period studied. These results are similar to those of two larger previous schedules performed in our center in relation to the same point of followup.
journal_name
Brachytherapyjournal_title
Brachytherapyauthors
Rovirosa Á,Ascaso C,Herreros A,Sánchez J,Holub K,Camarasa A,Sabater S,Oses G,García-Miguel J,Rivera Y,Arenas Mdoi
10.1016/j.brachy.2016.10.001subject
Has Abstractpub_date
2017-01-01 00:00:00pages
147-152issue
1eissn
1538-4721issn
1873-1449pii
S1538-4721(16)30557-8journal_volume
16pub_type
杂志文章相关文献
Brachytherapy文献大全abstract：OBJECTIVES:To evaluate the interim outcomes of low-dose-rate permanent brachytherapy (PB) combined with short-term androgen deprivation therapy (ADT) in Japanese men with intermediate-risk prostate cancer excluding those with a Gleason score of 4+3. METHODS:The Protocol-intermediate-risk group (Protocol-IRG) was defin...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2014.09.001
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:This study was undertaken to determine the feasibility of perioperative high-dose-rate brachytherapy (PHDRB) as an adjunct to salvage surgery in primary advanced or recurrent gynecologic cancer. METHODS:Twenty-five patients with either locally advanced (n = 4) or recurrent (n = 21) gynecologic cancer suitab...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2006.07.001
更新日期：2006-10-01 00:00:00
abstract：PURPOSE:For selected early breast cancers, intraoperative radiation therapy (IORT) at the time of lumpectomy can be an efficient alternative to fractionated whole breast radiation therapy (WBRT). However, some patients are later recommended WBRT after IORT due to surgical pathologic findings. To understand risk factor ...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2016.09.012
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:The objective of this overview was to critically evaluate the effect of polyethylene glycol (PEG)-based hydrogel spacers during prostate brachytherapy with regard to dosimetric and clinical benefits, as well as procedure-related toxicity. METHODS AND MATERIALS:A systematic search in the PubMed database was per...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2019.08.009
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:To determine whether potential extraprostatic extension (EPE) of prostate adenocarcinoma is covered by the prescribed dose when permanent 125I implants are planned with a 5-mm treatment margin. METHODS AND MATERIALS:The postimplant dosimetry of 60 consecutive 125I prostate implants was analyzed to determine wh...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2003.09.002
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:Androgen deprivation therapy (ADT) has been shown to improve survival for men with unfavorable-risk prostate cancer (PCa). We investigated the utilization and factors associated with the omission of ADT in radiation-managed high-risk PCa. METHODS AND MATERIALS:We used the National Cancer Database to identify m...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2016.07.001
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:With an aim to evaluate and report high dose date interstitial brachytherapy (HDR-ISBT) in vulvar cancers, we undertook this retrospective analysis. METHODS AND MATERIALS:Histologically proven vulvar cancers treated with HDR-ISBT between 2001 and 2016 were analyzed. Radiotherapy details, clinical outcome in te...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2016.10.003
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:Although current Delphi Consensus guidelines do not recommend a specific definition of biochemical recurrence after partial gland therapy, these guidelines acknowledge that serial prostate-specific antigen (PSA) tests remain the best marker for monitoring disease after treatment. The purpose of this study was t...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2018.12.001
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:The aim of this study was to estimate the incidence of complications after (90)Y microsphere radioembolization for unresectable hepatic tumors and evaluate risk factors for late complications. METHODS AND MATERIALS:A cohort of 112 consecutive patients from two institutions underwent (90)Y microsphere radioembo...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2013.05.008
更新日期：2013-11-01 00:00:00
abstract：PURPOSE:The American Brachytherapy Society (ABS) consensus guidelines for high-dose-rate (HDR) prostate brachytherapy suggest 11 different dose constraints for the urethra. The purpose of this study is to evaluate whether a single urethral constraint of D0.1 cm3 < 110% could meet all the proposed ABS urethral constrain...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2019.12.001
更新日期：2020-01-01 00:00:00
abstract：:While brachytherapy applications are not widely used for cancer diagnoses in the upper GI tract (including the esophagus, liver, stomach, and pancreas), they have a clear role in palliation and symptom management and occasionally definitive locoregional treatment. With the increasing use of image-guided techniques, th...
journal_title：Brachytherapy
pub_type： 杂志文章,评审
doi：10.1016/j.brachy.2020.11.010
更新日期：2020-12-22 00:00:00
abstract：OBJECTIVES:Men with higher body mass index (BMI) tend to have more fatty tissue in prostate-rectum interface, which may reduce the rectal wall dose by the inverse square law. We hypothesized that men with higher BMI will have a lower dose to the rectal wall and less rectal toxicity after permanent prostate implant. ME...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2008.12.001
更新日期：2009-04-01 00:00:00
abstract：PURPOSE:To describe in detail British Columbia (BC) Cancer Agency (BCCA) Provincial Prostate Brachytherapy (PB) Quality Assurance (QA) Program. METHODS AND MATERIALS:The BCCA PB Program was established in 1997. It operates as one system, unified and supported by electronic and information systems, making it a single P...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2012.03.006
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:To quantify needle migration and dosimetric impact in high-dose-rate brachytherapy for prostate cancer and propose a threshold for needle migration. METHODS AND MATERIALS:Twenty-four high-risk prostate cancer patients treated with an HDR boost of 2 × 8.5 Gy were included. Patients received an MRI for planning ...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2017.08.005
更新日期：2018-01-01 00:00:00
abstract：PURPOSE:Adjuvant vaginal brachytherapy (VB) is a well-established and effective radiation treatment modality in women with early-stage endometrial carcinoma. We sought to evaluate and update published trends in the utilization of VB vs. other radiation therapy modalities (pelvic external beam radiation therapy (EBRT) o...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2016.06.012
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:To assess the safety, feasibility, and efficacy of free-hand intraoperative multicatheter breast implant (FHIOMBI) and perioperative high-dose-rate brachytherapy (PHDRBT) in early breast cancer. METHODS AND MATERIALS:Patients with early breast cancer candidates for breast conservative surgery (BCS) were prospe...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2016.03.001
更新日期：2016-07-01 00:00:00
abstract：PURPOSE:The purpose of this study was to evaluate the incidence of late severe (≥Grade 3) urinary toxicity and the long-term efficacy after low-dose-rate brachytherapy (LDR-BT) in patients with localized prostate cancer (PCa). METHODS AND MATERIALS:During the years 1999-2008, 241 patients with PCa who underwent LDR-BT...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2019.05.005
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:To provide an MRI based functional anatomy guide to prostate brachytherapy. METHODS AND MATERIALS:We performed a narrative review of periprostatic functional anatomy and the significance of this anatomy in prostate brachytherapy treatment planning. RESULTS:MRI has improved delineation of gross tumor and criti...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2016.11.009
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:Dose escalation has been shown beneficial in prostate cancer. Brachytherapy (BT) provides an opportunity for dose escalation beyond what can be safely delivered using only teletherapy methods. The purpose of this study was to determine cancer control and morbidity of external beam radiation therapy (EBRT) plus ...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2009.01.002
更新日期：2009-04-01 00:00:00
abstract：INTRODUCTION:Substantial as opposed to focal or no lymphovascular space invasion (LVSI) is proposed as an independent adverse prognostic factor in patients with early-stage endometrioid endometrial cancer (EEC). We reviewed outcomes of patients treated with adjuvant vaginal brachytherapy (VB) alone in a single institut...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2020.12.006
更新日期：2021-01-20 00:00:00
abstract：PURPOSE:The radioactive gold grain applicator and seeds offer the flexibility necessary for effective use in the treatment of difficult sites of head-and-neck cancers. This study reviews our experience with gold grain (198Au) implants in locally advanced head-and-neck cancer to demonstrate their efficacy and feasibilit...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/s1538-4721(02)00054-5
更新日期：2002-01-01 00:00:00
abstract：PURPOSE:The purpose of this study was to report our experience regarding the development of a low-cost multichannel vaginal cylinder applicator for superficial and recurrent vaginal tumors. METHODS AND MATERIALS:The applicator mold was created by applying heated wax sheets in layers around a plastic tube. Interstitial...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2020.05.001
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:The British Columbia Cancer Agency has been performing iodine-125 prostate brachytherapy since 1998, initially using loose seeds and phasing into the exclusive use of RAPIDStrand (RS) (Oncura Inc., Plymouth Meeting, PA) by November 2000. The aim of this study was to investigate rates of biochemical no evidence ...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2011.01.011
更新日期：2011-11-01 00:00:00
abstract：PURPOSE:The purpose of this work was to evaluate whether the delivered dose to the skin surface and at the prescription depth when using a Freiburg flap applicator is in agreement with the one predicted by the treatment planning system (TPS) using the TG-43 dose-calculation formalism. METHODS AND MATERIALS:Monte Carlo...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2011.11.005
更新日期：2012-11-01 00:00:00
abstract：PURPOSE:We sought to develop an activity nomogram for magnetic resonance (MR)-planned permanent seed prostate brachytherapy to improve quality assurance through a secondary dosimetric check. METHODS AND MATERIALS:Patients undergoing MRI-assisted radiosurgery (MARS), whereby MRI is used for preoperative planning and po...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2019.10.002
更新日期：2020-01-01 00:00:00
abstract：UNLABELLED:PURPOSE/INTRODUCTION: To safely irradiate retroperitoneal targets as paraaortic lymph node by separating abdominal at-risk organs from the target during irradiation, we created a percutaneous paravertebral approach of high-dose-rate brachytherapy with hyaluronate gel injection (HGI). We report a case treated...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2011.12.004
更新日期：2013-01-01 00:00:00
abstract：PURPOSE:To explore the dosimetric advantage of target volume and surrounding normal tissue by using interstitial (IS) brachytherapy (BT) based on three-dimensional CT in locally advanced cervical cancer, as a simple and effective clinical treatment approach. METHODS AND MATERIALS:Fifty-two patients with poor tumor res...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2016.06.004
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:Low-dose-rate brachytherapy using iodine-125 seeds is a highly efficacious treatment for low-risk prostate cancer. We propose a bioeffect model may be used to target an ablative dose to the tumor with a lower, therapeutic dose to low-risk regions to maintain high rates of tumor control with reduced toxicity. We...
journal_title：Brachytherapy
pub_type： 杂志文章,多中心研究
doi：10.1016/j.brachy.2013.04.008
更新日期：2013-11-01 00:00:00
abstract：PURPOSE:Limited information is available comparing target volume and normal tissue dosimetry with the different techniques of partial breast irradiation (PBI). We present results of a dosimetric comparison of single catheter, balloon-based brachytherapy using the MammoSite catheter (BRT), 3D conformal radiation therapy...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2006.06.001
更新日期：2006-07-01 00:00:00
abstract：PURPOSE:Marriage has been associated with enhanced survival among cancer patients, but conflicting correlations have been suggested in cervical cancer. We assessed the impact of marital status on receipt of brachytherapy and survival in women with locally advanced cervical cancer. METHODS AND MATERIALS:Three thousand,...
journal_title：Brachytherapy
pub_type： 杂志文章
doi：10.1016/j.brachy.2019.04.273
更新日期：2019-01-01 00:00:00
