Multifocal bone and bone marrow lesions in children - MRI findings.

Abstract:

:Polyostotic bone and bone marrow lesions in children may be due to various disorders. Radiographically, lytic lesions may become apparent after loss of more than 50% of the bone mineral content. Scintigraphy requires osteoblastic activity and is not specific. MRI may significantly contribute to the correct diagnosis and management. Accurate interpretation of MRI examinations requires understanding of the normal conversion pattern of bone marrow in childhood and of the appearances of red marrow rests and hyperplasia. Differential diagnosis is wide: Malignancies include metastases, multifocal primary sarcomas and hematological diseases. Benign entities include benign tumors and tumor-like lesions, histiocytosis, infectious and inflammatory diseases, multiple stress fractures/reactions and bone infarcts/ischemia.

journal_name

Pediatr Radiol

journal_title

Pediatric radiology

authors

Raissaki M,Demetriou S,Spanakis K,Skiadas C,Katzilakis N,Velivassakis EG,Stiakaki E,Karantanas AH

doi

10.1007/s00247-016-3737-1

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

342-360

issue

3

eissn

0301-0449

issn

1432-1998

pii

10.1007/s00247-016-3737-1

journal_volume

47

pub_type

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