Abstract:
:Arterioles in various vascular beds have been often observed to have nonuniform diameters along the vessel axis. The effect of nonuniformity of arteriolar diameter on vascular resistance was investigated using a theoretical model of blood flow in arterioles. Viscous flow of a Newtonian fluid in tubes with periodically changing diameters along the tube axis was analyzed by a finite element method based on the Stokes equations. Vascular resistance for the nonuniform tube was computed over a spatial period of the variation in diameter and was compared to resistance for a uniform tube with a constant diameter equal to the mean diameter of the nonuniform tube. In all cases, resistance for a tube with a nonuniform diameter was larger than resistance for a uniform tube with a diameter equal to the mean diameter of the nonuniform tube. Increases in the amplitude of the variation in diameter resulted in a rapid increase in resistance when the period of the variation remained constant. On the other hand, as the period of the diameter variation increased when amplitude remained constant, resistance decreased and approached the values obtained under the assumption of a Poiseuille flow at each cross section of the tube in the limit of an infinite period. Our theoretical model was applied to our previous in vivo studies of vessel diameter nonuniformity for rabbit mesentery arterioles in a contracted state. It was shown that vascular resistance calculated by our model was 2 to 11% higher than resistance obtained for a uniform tube with a diameter equal to the mean diameter of the arteriole.
journal_name
Microvasc Resjournal_title
Microvascular researchauthors
Sugihara-Seki M,Minamiyama M,Hanai Sdoi
10.1016/0026-2862(89)90023-xsubject
Has Abstractpub_date
1989-09-01 00:00:00pages
148-54issue
2eissn
0026-2862issn
1095-9319pii
0026-2862(89)90023-Xjournal_volume
38pub_type
杂志文章abstract::Thermal injuries of more than 20% body surface area (BSA) result in systemic capillary leakage with subsequent edema. This can similarly be induced by burn plasma transfer (BPT) from burned individuals to healthy rats. We evaluated if cerium nitrate (CN) bathing can prevent edema after BPT. Therefore, donor rats (DR) ...
journal_title:Microvascular research
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更新日期:2000-03-01 00:00:00
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更新日期:2019-09-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00
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更新日期:2018-09-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:Microvascular research
pub_type: 杂志文章
doi:10.1016/0026-2862(90)90008-f
更新日期:1990-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:1996-03-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:1993-09-01 00:00:00
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journal_title:Microvascular research
pub_type: 杂志文章
doi:10.1006/mvre.1993.1016
更新日期:1993-03-01 00:00:00