Hydrogen sulfide enhances pancreatic β-cell differentiation from human tooth under normal and glucotoxic conditions.

abstract：AIM:Evaluation of survival, proliferation and neurodifferentiation of dental stem cells from the apical papilla (SCAP) in fibrin hydrogels. We hypothesized that fibrin composition will influence cell behavior. METHODS:Modulus, pore and fiber size were measured. SCAP in vitro viability, proliferation and neural differe...

journal_title：Regenerative medicine

authors： Germain L,De Berdt P,Vanacker J,Leprince J,Diogenes A,Jacobs D,Vandermeulen G,Bouzin C,Préat V,Dupont-Gillain C,des Rieux A

更新日期：2015-01-01 00:00:00

abstract：AIM:To perform an early cost-effectiveness analysis of in vitro expanded myoblasts (IVM) and minced myofibers versus midurethral slings (MUS) for surgical treatment of female stress urinary incontinence. METHODS:Cost-effectiveness and sensitivity analyses were performed using a decision tree comprising previously publ...

journal_title：Regenerative medicine

authors： Vilsbøll AW,Mouritsen JM,Jensen LP,Bødker N,Holst AW,Pennisi CP,Ehlers L

更新日期：2018-04-01 00:00:00

abstract：:Founded in 2009 and headquartered in Glasgow, Scotland, UK, Sistemic Ltd has developed from a thought in the minds of four scientists into a company working globally to play its part in delivering the exciting opportunities for improvements in human health presented by cell therapies and regenerative medicine products...

journal_title：Regenerative medicine

authors： Reid J

更新日期：2013-09-01 00:00:00

abstract：:Among the many international conferences in the field of stem cells and regenerative medicine, WSCS is distinct in focusing its efforts to serve as the meeting point by multisector communities of research, clinics, industry, regulation, policy making and ethics. All are aiming at advancing stem cell innovation and new...

journal_title：Regenerative medicine

authors： Hasegawa K,Asada T,Sengoku S,Nakatsuji N

更新日期：2015-05-01 00:00:00

abstract：:Diabetes mellitus represents a global epidemic affecting over 350 million patients worldwide and projected by the WHO to surpass the 500 million patient mark within the next two decades. Besides Type 1 and Type 2 diabetes mellitus, the study of the endocrine compartment of the pancreas is of great translational intere...

journal_title：Regenerative medicine

authors： Ricordi C,Inverardi L,Domínguez-Bendala J

更新日期：2012-11-01 00:00:00

abstract：:Aim: To describe the successful treatment of a Baker's cyst in the setting of post-traumatic osteoarthritis using ultrasound-guided injection of platelet-rich plasma. Setting: Outpatient sports clinic. Patient: 29-year old male basketball player. Case description: The patient presented with 2-months history of right k...

journal_title：Regenerative medicine

authors： Song B,Yeh PC,Jayaram P

更新日期：2020-06-01 00:00:00

abstract：:Spinal cord injury (SCI) is a devastating traumatic injury resulting in paralysis or sensory deficits due to tissue damage and the poor ability of axons to regenerate across the lesion. Despite extensive research, there is still no effective treatment that would restore lost function after SCI. A possible therapeutic ...

journal_title：Regenerative medicine

authors： Kubinová S,Syková E

更新日期：2012-03-01 00:00:00

abstract：:Regenerative engineering has been defined as the convergence of Advanced Materials Sciences, Stem Cell Sciences, Physics, Developmental Biology and Clinical Translation for the regeneration of complex tissues and organ systems. Anterior cruciate ligament (ACL) reconstruction necessitates the regeneration of bone, liga...

journal_title：Regenerative medicine

authors： Mengsteab PY,Nair LS,Laurencin CT

更新日期：2016-12-01 00:00:00

abstract：:Aim: We aimed to evaluate the capacity of the bilayer polylactic-co-glycolic acid (PLGA)/TGF-β3/adipose-derived mesenchymal stem cell (ADSC) construct used to repair cartilage defects and the role of ADSCs in the repair process in vivo. Materials & methods: Defects were created surgically on the femoropatellar groove ...

journal_title：Regenerative medicine

authors： Yang ZG,Tang RF,Qi YY,Chen WP,Xiong Y,Wu LD

更新日期：2020-06-01 00:00:00

abstract：:Since the first pioneering scientists explored the potential of using human cells for therapeutic purposes the branch of regenerative medicine has evolved to become a mature industry. The focus has switched from 'what can be done' to 'what can be commercialized'. Timely health economic evaluation supports successful m...

journal_title：Regenerative medicine

authors： Koerber F,Rolauffs B,Rogowski W

更新日期：2013-11-01 00:00:00

abstract：AIM:Demonstrate that periadventitial delivery of adipose-derived mesenchymal stem cells (ADMSCs) slows aneurysm progression in an established murine elastase-perfusion model of abdominal aortic aneurysm (AAA). MATERIALS & METHODS:AAAs were induced in C57BL/6 mice using porcine elastase. During elastase perfusion, a de...

journal_title：Regenerative medicine

authors： Blose KJ,Ennis TL,Arif B,Weinbaum JS,Curci JA,Vorp DA

更新日期：2014-01-01 00:00:00

abstract：:Cord blood platelet gel is prepared by activation of coagulation in a platelet concentrate obtained from cord blood. During the process of clot formation, platelet alpha-granules release growth factors that promote tissue repair. However, in the form of gel, it is not possible to inject it into small, narrow and deep ...

journal_title：Regenerative medicine

authors： Bisceglia G,Santodirocco M,Faienza A,Mastrodonato N,Urbano F,Totaro A,Bazzocchi F,Mauro LD

更新日期：2020-01-01 00:00:00

abstract：:Latest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from nonacademic institutions in March 2020. ...

journal_title：Regenerative medicine

authors： Ilic D,Liovic M

更新日期：2020-07-01 00:00:00

abstract：:Dimethyl sulfoxide (DMSO) is the cryoprotectant of choice for most animal cell systems since the early history of cryopreservation. It has been used for decades in many thousands of cell transplants. These treatments would not have taken place without suitable sources of DMSO that enabled stable and safe storage of bo...

journal_title：Regenerative medicine

authors： Awan M,Buriak I,Fleck R,Fuller B,Goltsev A,Kerby J,Lowdell M,Mericka P,Petrenko A,Petrenko Y,Rogulska O,Stolzing A,Stacey GN

更新日期：2020-03-01 00:00:00

abstract：:The thymus is required for generation of a self-tolerant, self-restricted T-cell repertoire. The capacity to manipulate or replace thymus function therapeutically would be beneficial in a variety of clinical settings, including for improving recovery following bone marrow transplantation, restoring immune system funct...

journal_title：Regenerative medicine

authors： Bredenkamp N,Jin X,Liu D,O'Neill KE,Manley NR,Blackburn CC

更新日期：2015-01-01 00:00:00

abstract：:Biological regeneration is proving to be an increasingly attractive alternative/complement to prosthetic replacement of tissues and organs. In cell-based therapeutic approaches, cells are manipulated in vitro and administered to patients as living and dynamic biological agents. In this review, we have focused on the r...

journal_title：Regenerative medicine

authors： De Bari C,Pitzalis C,Dell'Accio F

更新日期：2006-01-01 00:00:00

abstract：:Aim: Cell repopulation of tissue-engineered vascular grafts (TEVGs) from decellularized arterial scaffolds is limited by dense concentric tunica media layers which impede cells migrating radially between the layers. We aimed to develop and validate a new microneedle device to modify decellularized carotid arteries wit...

journal_title：Regenerative medicine

authors： Eufrásio-da-Silva T,Ruiz-Hernandez E,O'Dwyer J,Picazo-Frutos D,Duffy GP,Murphy BP

更新日期：2019-11-01 00:00:00

abstract：AIMS:To evaluate the safety and efficacy of cell therapies administered acutely/sub-acutely after stroke. METHODS:Five databases were searched for studies examining the safety/efficacy of cell therapies administered ≤90 days post-stroke. Reporting quality and adherence to research guidelines were evaluated. Safety and...

journal_title：Regenerative medicine

authors： Unsworth DJ,Mathias JL,Dorstyn DS

更新日期：2016-10-01 00:00:00

abstract：:Diabetes mellitus, which affects 346 million people, is one of the leading causes of death worldwide. Pancreatic β-cells, existing in the islets of Langerhans, play central roles in the progression of diabetes. An efficient strategy to produce functional pancreatic β-cells is important for both transplantation therapy...

journal_title：Regenerative medicine

authors： Kao DI,Chen S

更新日期：2012-07-01 00:00:00

abstract：AIMS:Murine 3T3 feeder cells are commonly used for stem cell expansion. Although 'feeder-free' systems are being developed for a variety of stem cells including embryonic, the use of feeder cells currently remains optimal for the expansion of epithelial stem cells. In this study, MRC-5, a human embryonic fibroblast cel...

journal_title：Regenerative medicine

authors： Notara M,Haddow DB,MacNeil S,Daniels JT

更新日期：2007-11-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have tremendous potential for regenerative medicine, and have been researched for the treatment of cardiovascular diseases. MSCs are a promising cell type because of their ease of isolation and expansion, their multipotency and their low immunogenicity. However, in order to fully utilize ...

journal_title：Regenerative medicine

authors： Huang NF,Li S

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Human embryonic stem cells (hESCs) can differentiate into any human cell type, including CNS cells, and thus have high potential in regenerative medicine. Several protocols exist for neuronal differentiation of hESCs, which do not necessarily work for all hESC lines. MATERIALS & METHODS:We tested the differ...

journal_title：Regenerative medicine

authors： Lappalainen RS,Salomäki M,Ylä-Outinen L,Heikkilä TJ,Hyttinen JA,Pihlajamäki H,Suuronen R,Skottman H,Narkilahti S

更新日期：2010-09-01 00:00:00

abstract：:Professor Coffey joined the faculty at the University of Oxford in 1987 on completing his doctoral work. In 1989, he was awarded a personal Royal Society Research Fellowship, at the same time moving to the University of Sheffield to establish a new laboratory for retinal transplantation. After 14 years at the Universi...

journal_title：Regenerative medicine

authors： Coffey P

更新日期：2009-07-01 00:00:00

abstract：:Background: To evaluate whether subtenon injection of platelet-rich plasma (PRP) with retinal electromagnetic stimulation (rEMS) is effective in therapy-resistant chronic central serous chorioretinopathy (CSCR). Design: Prospective, sequential. Materials & methods: The study included 22 eyes with resistant chronic CSC...

journal_title：Regenerative medicine

authors： Arslan U,Özmert E

更新日期：2020-08-01 00:00:00

abstract：:The cornea at the front of the eye is covered by an epithelium. This epithelium is maintained by stem cells located at the periphery of the cornea, in a region known as the limbus. Because this region harbors the stem cells for the corneal epithelium, the so-called limbal stem cells, its culture provides considerable ...

journal_title：Regenerative medicine

authors： Osei-Bempong C,Henein C,Ahmad S

更新日期：2009-05-01 00:00:00

abstract：AIMS:To assess the potential of electrospun poly(lactide-co-glycolide) membranes to provide a biodegradable cell carrier system for limbal epithelial cells. MATERIAL & METHODS:50:50 poly(lactide-co-glycolide) scaffolds were spun, sterilized and seeded with primary rabbit limbal epithelial cells. Cells were cultured on...

journal_title：Regenerative medicine

authors： Deshpande P,McKean R,Blackwood KA,Senior RA,Ogunbanjo A,Ryan AJ,MacNeil S

更新日期：2010-05-01 00:00:00

abstract：:In the past decade, stem cell therapy has been increasingly employed for the treatment of various diseases. Subsequently, there has been a great interest in the manufacture of stem cells under good manufacturing practice, which is required by law for their use in humans. The cells for sight Stem Cell Therapy Research ...

journal_title：Regenerative medicine

authors： Sheth-Shah R,Vernon AJ,Seetharaman S,Neale MH,Daniels JT

更新日期：2016-04-01 00:00:00

abstract：:In soft tissue repair, there are several surgical options such as nondegradable, inert, synthetic, biodegradable implants or autologous tissue transplantation. However, the potential of using autologous adult stem cells derived from fat tissue is quickly becoming a clinical reality. The possibility of using an abundan...

journal_title：Regenerative medicine

authors： Cherubino M,Marra KG

更新日期：2009-01-01 00:00:00

abstract：:Inherited epidermolysis bullosa (EB) is a family of rare genetic skin disorders characterized by structural and mechanical fragility of skin and mucosal membranes. The main feature of EB is the presence of recurrent skin blistering or erosions, which have a profound impact in the quality of life of EB patients and, in...

journal_title：Regenerative medicine

authors： Carulli S,Contin R,De Rosa L,Pellegrini G,De Luca M

更新日期：2013-07-01 00:00:00

abstract：:The Tissue Engineering and Regenerative Medicine International Society-Asia Pacific (TERMIS-AP) annual meeting was held in Sydney, Australia from 15-17 September 2010 and highlighted the latest developments in tissue engineering and regenerative medicine in the Asia-Pacific region. Several of the plenary lectures focu...

journal_title：Regenerative medicine

authors： Frith JE,Hudson JE,Cooper-White JJ

更新日期：2011-03-01 00:00:00