The metabolic flux regulation of Klebsiella pneumoniae based on quorum sensing system.

abstract：:The physiological function of the pancreas is controlled by the circadian clock. The aim of this study was to determine whether aging-induced changes in glucose homeostasis affect properties of the circadian clock in the pancreas and/or its sensitivity to disturbances in environmental lighting conditions. mPer2Luc mic...

journal_title：Scientific reports

authors： Novosadová Z,Polidarová L,Sládek M,Sumová A

更新日期：2018-08-03 00:00:00

abstract：:MicroRNAs play critical role in the development and progression of various diseases. Predicting potential miRNA-disease associations from vast amount of biological data is an important problem in the biomedical research. Considering the limitations in previous methods, we developed Regularized Least Squares for MiRNA-...

journal_title：Scientific reports

authors： Chen X,Yan GY

更新日期：2014-06-30 00:00:00

abstract：:Evaluations of restoration success usually focus on the structural aspects of ecosystems. Pollination, as an important functional aspect, is often overlooked. Here, the shifts in pollinator assemblage and pollen limitation in the desert shrub Caragana microphylla were examined along a restoration gradient in Horqin Sa...

journal_title：Scientific reports

authors： Pan CC,Qu H,Feng Q,Liu LD,Zhao HL,Li YL,Li YQ,Zhang TH,Liu XP

更新日期：2017-12-04 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep31347. ...

journal_title：Scientific reports

authors： Zhu W,Wang L,Dong Z,Chen X,Song F,Liu N,Yang H,Fu J

更新日期：2018-05-11 00:00:00

abstract：:The dependency property and self-recovery of failure nodes both have great effects on the robustness of networks during the cascading process. Existing investigations focused mainly on the failure mechanism of static dependency groups without considering the time-dependency of interdependent nodes and the recovery mec...

journal_title：Scientific reports

authors： Bai YN,Huang N,Wang L,Wu ZX

更新日期：2016-11-28 00:00:00

abstract：:Mitochondria behave as functional and structural hubs for innate defense against intracellular infection. While the mitochondrial membrane serves as a platform for the assembly of signaling complexes activated by intracellular infection, various danger molecules derived from impaired mitochondria activate innate signa...

journal_title：Scientific reports

authors： Seo JH,Hwang CS,Yoo JY

更新日期：2020-07-07 00:00:00

abstract：:To examine the influence on postoperative endothelial cell density (ECD) caused by preoperative temperature change from 4 °C to room temperature in donor corneas for Descemet stripping automated endothelial keratoplasty (DSAEK). This retrospective, case-controlled comparison of 100 eyes that underwent DSAEK using impo...

journal_title：Scientific reports

authors： Kakisu K,Yamaguchi T,Shimazaki J

更新日期：2020-01-20 00:00:00

abstract：:Developing therapeutics that target multiple receptor signaling pathways in tumors is critical as therapies targeting single specific biomarker/pathway have shown limited efficacy in patients with cancer. In this study, we extensively characterized a bi-functional molecule comprising of epidermal growth factor recepto...

journal_title：Scientific reports

authors： Zhu Y,Bassoff N,Reinshagen C,Bhere D,Nowicki MO,Lawler SE,Roux J,Shah K

更新日期：2017-06-01 00:00:00

abstract：:Streptococcus mutans is known to be a major causative agent of dental caries, and strains expressing the cell surface collagen-binding Cnm protein contribute to the development of several systemic diseases. A relationship between tonsillar immunity and glomerulonephritis has been recognized in IgA nephropathy (IgAN), ...

journal_title：Scientific reports

authors： Ito S,Misaki T,Naka S,Wato K,Nagasawa Y,Nomura R,Otsugu M,Matsumoto-Nakano M,Nakano K,Kumagai H,Oshima N

更新日期：2019-12-27 00:00:00

abstract：:Two decades ago, a phenomenon resembling Landau damping was described in the synchronization of globally coupled oscillators: the evidence of a regime where the order parameter decays when linear theory predicts neutral stability for the incoherent state. We here show that such an effect is far more generic, as soon a...

journal_title：Scientific reports

authors： Qiu T,Zhang Y,Liu J,Bi H,Boccaletti S,Liu Z,Guan S

更新日期：2015-12-14 00:00:00

abstract：:As it is altered by ionizing radiation, the vascular network is considered as a prime target in limiting normal tissue damage and improving tumor control in radiation therapy. Irradiation activates endothelial cells which then participate in the recruitment of circulating cells, especially by overexpressing cell adhes...

journal_title：Scientific reports

authors： Jaillet C,Morelle W,Slomianny MC,Paget V,Tarlet G,Buard V,Selbonne S,Caffin F,Rannou E,Martinez P,François A,Foulquier F,Allain F,Milliat F,Guipaud O

更新日期：2017-07-13 00:00:00

abstract：:Volumetric and morphometric studies have demonstrated structural abnormalities related to chronic epilepsies on a cohort- and population-based level. On a single-patient level, specific patterns of atrophy or cortical reorganization may be widespread and heterogeneous but represent potential targets for further person...

journal_title：Scientific reports

authors： Rummel C,Slavova N,Seiler A,Abela E,Hauf M,Burren Y,Weisstanner C,Vulliemoz S,Seeck M,Schindler K,Wiest R

更新日期：2017-09-07 00:00:00

abstract：:Non-availability of an ideal alternative for autografts in treating critical-size bone defects is a major challenge in orthopedics. Phytocompounds have been proven to enhance osteogenesis via various osteogenic signaling pathways, but its decreased bioavailability and increased renal clearance limit its application. I...

journal_title：Scientific reports

authors： Chandran SV,Vairamani M,Selvamurugan N

更新日期：2019-08-15 00:00:00

abstract：:We report the robust ferroelectric properties of (1 - x)(Bi1/2Na1/2)TiO3-x(Bi1/2K1/2)TiO3 (x = 33%) single crystals grown by a top-seeded solution growth process under a high oxygen-pressure (0.9 MPa) atmosphere. The sample exhibit a large remanent polarization of 48 μC/cm2 and a sizeable piezoelectric strain constant...

journal_title：Scientific reports

authors： Kitanaka Y,Noguchi Y,Miyayama M

更新日期：2019-12-17 00:00:00

abstract：:We report here the design and multiple functions of a new hierarchical nanotheronostic platform consisting of an upconversion nanoparticle (UCNP) core: shell with an additional mesoporous silica (mSiO2) matrix load shell containing sealed, high concentration of ICG molecules. We demonstrate that this UCNP@mSiO2-ICG na...

journal_title：Scientific reports

authors： Lv R,Wang D,Xiao L,Chen G,Xia J,Prasad PN

更新日期：2017-11-16 00:00:00

abstract：:Speaking involves coordination of multiple neuromotor systems, including respiration, phonation and articulation. Developing non-invasive imaging methods to study how the brain controls these systems is critical for understanding the neurobiology of speech production. Recent models and animal research suggest that reg...

journal_title：Scientific reports

authors： Correia JM,Caballero-Gaudes C,Guediche S,Carreiras M

更新日期：2020-03-11 00:00:00

abstract：:Recent evidence points at the role that human endogenous retroviruses (HERVs) may play through the activation of genes integrated across the human genome. Although a variety of genetic/epigenetic mechanisms maintain most HERVs silenced, independent environmental stimuli including infections may transactivate endogenou...

journal_title：Scientific reports

authors： Niegowska M,Wajda-Cuszlag M,Stępień-Ptak G,Trojanek J,Michałkiewicz J,Szalecki M,Sechi LA

更新日期：2019-04-18 00:00:00

abstract：:The western North-Atlantic coast experienced major coastal floods in recent years. Coastal floods are primarily composed of tides and storm surges due to tropical (TCs) and extra-tropical cyclones (ETCs). We present a reanalysis from 1988 to 2015 of extreme sea levels that explicitly include TCs for the western North-...

journal_title：Scientific reports

authors： Muis S,Lin N,Verlaan M,Winsemius HC,Ward PJ,Aerts JCJH

更新日期：2019-03-04 00:00:00

abstract：:The combined regulation of a network of inhibitory and activating T cell receptors may be a critical step in the development of chronic HCV infection. Ex vivo HCV MHC class I + II tetramer staining and bead-enrichment was performed with baseline and longitudinal PBMC samples of a cohort of patients with acute, chronic...

journal_title：Scientific reports

authors： Ackermann C,Smits M,Woost R,Eberhard JM,Peine S,Kummer S,Marget M,Kuntzen T,Kwok WW,Lohse AW,Jacobs T,Boettler T,Schulze Zur Wiesch J

更新日期：2019-07-23 00:00:00

abstract：:The strange three-dimensional flight behaviour of slowly spinning soccer balls is one of the most interesting and unknown phenomenon associated with the trajectories of sports balls. Many spectators have experienced numerous exciting and emotional instances while observing the curious flight behaviour of these balls. ...

journal_title：Scientific reports

authors： Mizota T,Kurogi K,Ohya Y,Okajima A,Naruo T,Kawamura Y

更新日期：2013-01-01 00:00:00

abstract：:Multifunctional materials with more than two good properties are widely required in modern industries. However, some properties are often trade-off with each other by single microstructural designation. For example, nanostructured materials have high strength, but low ductility and thermal stability. Here by means of ...

journal_title：Scientific reports

authors： Zhang YS,Zhao YH,Zhang W,Lu JW,Hu JJ,Huo WT,Zhang PX

更新日期：2017-01-06 00:00:00

abstract：:Liquid foams are classified into a dry foam and a wet foam, empirically judging from the liquid fraction or the shape of the gas bubbles. It is known that physical properties such as elasticity and diffusion are different between the dry foam and the wet foam. Nevertheless, definitions of those states have been vague ...

journal_title：Scientific reports

authors： Furuta Y,Oikawa N,Kurita R

更新日期：2016-11-22 00:00:00

abstract：:While the Wnt/β-catenin pathway plays a critical role in the maintenance of the zonation of ammonia metabolizing enzymes in the adult liver, the mechanisms responsible for inducing zonation in the embryo are not well understood. Herein we address the spatiotemporal role of the Wnt/β-catenin pathway in the development ...

journal_title：Scientific reports

authors： Burke ZD,Reed KR,Yeh SW,Meniel V,Sansom OJ,Clarke AR,Tosh D

更新日期：2018-02-09 00:00:00

abstract：:The lateral motion of a magnetic skyrmion, arising because of the skyrmion Hall effect, imposes a number of restrictions on the use of this spin state in the racetrack memory. A skyrmionium is a more promising spin texture for memory applications, since it has zero total topological charge and propagates strictly alon...

journal_title：Scientific reports

authors： Kolesnikov AG,Stebliy ME,Samardak AS,Ognev AV

更新日期：2018-11-16 00:00:00

abstract：:Evidence of extinction debts for the global distributions of forest-dwelling reptiles, mammals and amphibians was tested and the debt magnitude was estimated and mapped. By using different correlation tests and variable importance analysis, the results showed that spatial richness patterns for the three forest-dwellin...

journal_title：Scientific reports

authors： Chen Y,Peng S

更新日期：2017-03-16 00:00:00

abstract：:The amphibian chytrid fungus Batrachochytrium dendrobatidis is an emerging infectious pathogen present on every continent except Antarctica. It causes the disease chytridiomycosis in a subset of species but does not always result in disease or death for every host. Ambient temperature influences both amphibian metabol...

journal_title：Scientific reports

authors： Campbell L,Bower DS,Clulow S,Stockwell M,Clulow J,Mahony M

更新日期：2019-01-14 00:00:00

abstract：:Knowledge of brain correlates of postural control is limited by the technical difficulties in performing controlled experiments with currently available neuroimaging methods. Here we present a system that allows the measurement of anticipatory postural adjustment of human legs to be synchronized with the acquisition o...

journal_title：Scientific reports

authors： de Lima-Pardini AC,de Azevedo Neto RM,Coelho DB,Boffino CC,Shergill SS,de Oliveira Souza C,Brant R,Barbosa ER,Cardoso EF,Teixeira LA,Cohen RG,Horak FB,Amaro E Jr

更新日期：2017-02-23 00:00:00

abstract：:Rice stripe virus-infected females of the small brown planthopper (SBPH, Laodelphax striatellus) usually lay fewer eggs with a longer hatch period, low hatchability, malformation and retarded or defective development compared with healthy females. To explore the molecular mechanism of those phenomena, we analyzed the ...

journal_title：Scientific reports

authors： Liu B,Qin F,Liu W,Wang X

更新日期：2016-06-09 00:00:00

abstract：:Wolbachia, an endosymbiotic alpha-proteobacterium commonly found in insects, can inhibit the transmission of human pathogens by mosquitoes. Biocontrol programs are underway using Aedes aegypti mosquitoes trans-infected with a non-natural Wolbachia strain to reduce dengue virus transmission. Less is known about the imp...

journal_title：Scientific reports

authors： Straub TJ,Shaw WR,Marcenac P,Sawadogo SP,Dabiré RK,Diabaté A,Catteruccia F,Neafsey DE

更新日期：2020-08-14 00:00:00

abstract：:There is a definite relationship between alcohol consumption and colorectal cancer (CRC) development. We investigated effect of alcohol consumption on CRC patients' progression and prognosis by utilizing epidemiological data and found patients with alcohol consumption increased risks of tumor-node-metastasis (TNM), or...

journal_title：Scientific reports

authors： Zhao H,Chen D,Cao R,Wang S,Yu D,Liu Y,Jiang Y,Xu M,Luo J,Wang S

更新日期：2018-06-05 00:00:00