Abstract:
:The DNA Data Bank of Japan (DDBJ) (http://www.ddbj.nig.ac.jp) has been providing public data services for thirty years (since 1987). We are collecting nucleotide sequence data from researchers as a member of the International Nucleotide Sequence Database Collaboration (INSDC, http://www.insdc.org), in collaboration with the US National Center for Biotechnology Information (NCBI) and European Bioinformatics Institute (EBI). The DDBJ Center also services Japanese Genotype-phenotype Archive (JGA), with the National Bioscience Database Center to collect human-subjected data from Japanese researchers. Here, we report our database activities for INSDC and JGA over the past year, and introduce retrieval and analytical services running on our supercomputer system and their recent modifications. Furthermore, with the Database Center for Life Science, the DDBJ Center improves semantic web technologies to integrate and to share biological data, for providing the RDF version of the sequence data.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Mashima J,Kodama Y,Fujisawa T,Katayama T,Okuda Y,Kaminuma E,Ogasawara O,Okubo K,Nakamura Y,Takagi Tdoi
10.1093/nar/gkw1001subject
Has Abstractpub_date
2017-01-04 00:00:00pages
D25-D31issue
D1eissn
0305-1048issn
1362-4962pii
gkw1001journal_volume
45pub_type
杂志文章abstract::To determine whether methylation changes in specific DNA sequences of the albumin and AFP genes are implicated in the modulation of transcriptional activity during rat liver development and neoplasia we have analysed the methylation pattern of C-C-G-G sequences within these genes in DNA isolated from fetal and adult h...
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journal_title:Nucleic acids research
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