Halogenated indoles eradicate bacterial persister cells and biofilms.

abstract：:Mathematical models have been used from growth kinetic simulation to gen regulatory networks prediction for B. thuringiensis culture. However, this culture is a time dependent dynamic process where cells physiology suffers several changes depending on the changes in the cell environment. Therefore, through its culture...

journal_title：AMB Express

authors： Navarro-Mtz AK,Pérez-Guevara F

更新日期：2014-12-01 00:00:00

abstract：:Lactic acid bacteria are industrially important microorganisms recognized for fermentative ability mostly in their probiotic benefits as well as lactic acid production for various applications. Fermentation conditions such as concentration of initial glucose in the culture, concentration of lactic acid accumulated in ...

journal_title：AMB Express

authors： Othman M,Ariff AB,Wasoh H,Kapri MR,Halim M

更新日期：2017-11-27 00:00:00

abstract：:The major platform for high level recombinant protein production is based on genetically modified microorganisms like Escherichia coli (E. coli) due to its short dividing time, ability to use inexpensive substrates and additionally, its genetics is comparatively simple, well characterized and can be manipulated easily...

journal_title：AMB Express

authors： Kangwa M,Yelemane V,Polat AN,Gorrepati KD,Grasselli M,Fernández-Lahore M

更新日期：2015-12-01 00:00:00

abstract：:The potential of Lactobacillus johnsonii NCC 533 to metabolize chlorogenic acids from green coffee extract was investigated. Two enzymes, an esterase and a hydroxycinnamate decarboxylase (HCD), were involved in this biotransformation. The complete hydrolysis of 5-caffeoylquinic acid (5-CQA) into caffeic acid (CA) by L...

journal_title：AMB Express

authors： Bel-Rhlid R,Thapa D,Kraehenbuehl K,Hansen CE,Fischer L

更新日期：2013-05-21 00:00:00

abstract：:MicroRNAs (miRs) have shown tremendous potential to act as therapeutic targets for cancer treatment. In this context, the present study was designed to investigate the potential of miR-143 in the treatment of breast cancer. Results showed that miR-143 to be significantly (P < 0.05) downregulated in breast cancer tissu...

journal_title：AMB Express

authors： Du Y,Zhang J,Meng Y,Huang M,Yan W,Wu Z

更新日期：2020-07-31 00:00:00

abstract：:Chlorothalonil, a non-systemic and broad-spectrum fungicide, is widely used to control the pathogens of agricultural plants. Although microbial degradation of chlorothalonil is known, we know little about the colonization and degradation capacity of these microbes in the natural and semi-natural soil environments. The...

journal_title：AMB Express

authors： Zhang Q,Saleem M,Wang C

更新日期：2017-12-23 00:00:00

abstract：:The basidiospores of most Agaricomycetes are ballistospores. They are propelled off from their basidia at maturity when Buller's drop develops at high humidity at the hilar spore appendix and fuses with a liquid film formed on the adaxial side of the spore. Spores are catapulted into the free air space between hymenia...

journal_title：AMB Express

authors： Lakkireddy K,Kües U

更新日期：2017-12-01 00:00:00

abstract：:Despite the threat of Fusarium dieback posed due to ambrosia fungi cultured by ambrosia beetles such as Euwallacea spp., the wood-degradation mechanisms utilized by ambrosia fungi are not fully understood. In this study, we analyzed the 16S rRNA and 18S rRNA genes of the microbial community from the Ficus tree tunnel ...

journal_title：AMB Express

authors： Sakai K,Yamaguchi A,Tsutsumi S,Kawai Y,Tsuzuki S,Suzuki H,Jindou S,Suzuki Y,Kajimura H,Kato M,Shimizu M

更新日期：2020-05-24 00:00:00

abstract：:During industrial fermentation, Streptomyces clavuligerus F613-1 simultaneously produces primary product clavulanic acid (CA) and cephamycin C. The cephamycin C biosynthetic gene cluster and pathway have been basically elucidated and the CcaR positive regulator was found to control the cephamycin genes expression. How...

journal_title：AMB Express

authors： Fu J,Qin R,Zong G,Zhong C,Zhang P,Kang N,Qi X,Cao G

更新日期：2019-07-27 00:00:00

abstract：:Although high levels of staphylococcal phenol-soluble modulins (PSMs) in clinical methicillin-resistant Staphylococcus aureus (MRSA) has been shown to correlate with bacterial virulence, the PSMs expression in foodborne Staphylococcus aureus (S. aureus), as well as its association with staphylococcal food poisoning (S...

journal_title：AMB Express

authors： Wu X,Yang M,Fang X,Zhen S,Zhang J,Yang X,Qiao L,Yang Y,Zhang C

更新日期：2018-11-22 00:00:00

abstract：:The 70-kD heat shock proteins (Hsp70s) have been proved to be important for stress tolerance and protein folding and unfolding in almost all organisms. However, the functions of Hsp70s in mushroom are not well understood. In the present study, a hsp70 gene from Hypsizygus marmoreus, hmhsp70, was cloned and transferred...

journal_title：AMB Express

authors： Xu L,Gao J,Guo L,Yu H

更新日期：2020-01-18 00:00:00

abstract：:This study was demonstrated with a coculture fermentation system using sugar beet pulp (SBP) as a carbon source combining the cellulose-degrading bacterium Clostridium cellulovorans with microbial flora of methane production (MFMP) for the direct conversion of cellulosic biomass to methane (CH4). The MFMP was taken fr...

journal_title：AMB Express

authors： Tomita H,Okazaki F,Tamaru Y

更新日期：2019-02-18 00:00:00

abstract：:The utilization of inoculants containing Azospirillum is becoming more popular due to increasing reports of expressive gains in grain yields. However, incompatibility with pesticides used in seed treatments represents a main limitation for a successful inoculation. Therefore, in this study we searched for alternatives...

journal_title：AMB Express

authors： Fukami J,Nogueira MA,Araujo RS,Hungria M

更新日期：2016-03-01 00:00:00

abstract：:Cyclophosphamide (CPA) represents a widely used anti-cancer prodrug that is converted by liver cytochrome P450 (CYP) enzymes into the primary metabolite 4-hydroxycyclophosphamide (4-OH-CPA), followed by non-enzymatic generation of the bioactive metabolites phosphoramide mustard and acrolein. The use of human drug meta...

journal_title：AMB Express

authors： Steinbrecht S,Kiebist J,König R,Thiessen M,Schmidtke KU,Kammerer S,Küpper JH,Scheibner K

更新日期：2020-07-18 00:00:00

abstract：:Sweet potato vine (SPV) is an abundant agricultural waste, which is easy to obtain at low cost and has the potential to produce clean energy via anaerobic digestion (AD). The main objectives of this study were to reveal methane production and process stability of SPV and the mixtures with animal manure under various t...

journal_title：AMB Express

authors： Zhang E,Li J,Zhang K,Wang F,Yang H,Zhi S,Liu G

更新日期：2018-03-22 00:00:00

abstract：:Fusicocca-2,10(14)-diene (FCdiene) is a diterpene which is interesting as a precursor of the anti-cancer drug fusicoccin A and therefore for pharmaceutical applications. Production of FCdiene using a genetically modified Saccharomyces cerevisiae has been previously demonstrated with batch cultivations with a product c...

journal_title：AMB Express

authors： Halka LM,Nowacki C,Kleinschmidt A,Koenen K,Wichmann R

更新日期：2018-08-22 00:00:00

abstract：:Laccases are used for the conversion of biomass into fermentable sugars but it is difficult to produce high yields of active laccases in heterologous expression systems. We overcame this challenge by expressing Streptomyces cyaneus CECT 3335 laccase in Escherichia coli (ScLac) and we achieved a yield of up to 104 mg L...

journal_title：AMB Express

authors： Ece S,Lambertz C,Fischer R,Commandeur U

更新日期：2017-12-01 00:00:00

abstract：:Young barley leaf extract (YBL) contains beneficial substances such as fructans, minerals, and vitamins. The effects of YBL administration on the human colonic microbiota and its production of metabolites were evaluated using an in vitro model culture system. Fermentations were started by inoculating fecal samples fro...

journal_title：AMB Express

authors： Sasaki D,Sasaki K,Kadowaki Y,Aotsuka Y,Kondo A

更新日期：2019-11-13 00:00:00

abstract：:Extracellular enzymes play an important role in the growth and development of edible fungi. Extracellular enzyme activities have also become an important object of measurement. In this study, Agaricus brunnescens Peck, Coprinus comatus, and Pleurotus ostreatus were compared in terms of their enzyme production in liqui...

journal_title：AMB Express

authors： Huang L,Sun N,Ban L,Wang Y,Yang H

更新日期：2019-01-07 00:00:00

abstract：:Wolves (Canis lupus) and their domesticated and close relatives, dogs (Canis lupus familiaris), have great differences in their diets and living environments. To the best of our knowledge, the fundamental question of how the abundance and function of the gut microbiota of domestic dogs evolved to adapt to the changes ...

journal_title：AMB Express

authors： Lyu T,Liu G,Zhang H,Wang L,Zhou S,Dou H,Pang B,Sha W,Zhang H

更新日期：2018-08-02 00:00:00

abstract：:Cordyceps militaris is a type of entomogenous fungi and has been widely used as a medicinal fungus in Asia. Cordycepin produced by C. militaris has also been found to protect the liver. Moreover, deep ocean water (DOW) was proven to increase the functional compounds of functional fungi-fermented products. However, the...

journal_title：AMB Express

authors： Hung YP,Wang JJ,Wei BL,Lee CL

更新日期：2015-12-01 00:00:00

abstract：:In the present study, a methanogenic alkane-degrading (a mixture of C9 to C12n-alkanes) culture enriched from production water of a low-temperature oil reservoir was established and assessed. Significant methane production was detected in the alkane-amended enrichment cultures compared with alkane-free controls over a...

journal_title：AMB Express

authors： Ji JH,Zhou L,Mbadinga SM,Irfan M,Liu YF,Pan P,Qi ZZ,Chen J,Liu JF,Yang SZ,Gu JD,Mu BZ

更新日期：2020-02-01 00:00:00

abstract：:An exhaustive screening program was applied for scoring a promising L-asparaginase producing-isolate. The recovered isolate was identified biochemically and molecularly and its L-asparaginase productivity was optimized experimentally and by Response Surface Methodology. The produced enzyme was characterized experiment...

journal_title：AMB Express

authors： Abdelrazek NA,Elkhatib WF,Raafat MM,Aboulwafa MM

更新日期：2020-04-15 00:00:00

abstract：:Aspergillus aculeatus β-glucosidase 1 (AaBGL1), which promotes cellulose hydrolysis by Trichoderma cellulase system, was characterized and compared some properties to a commercially supplied orthologue in A. niger (AnBGL) to elucidate advantages of recombinant AaBGL1 (rAaBGL1) for synergistic effect on Trichoderma enz...

journal_title：AMB Express

authors： Baba Y,Sumitani JI,Tani S,Kawaguchi T

更新日期：2015-01-24 00:00:00

abstract：:Hydrogen gas represents a promising alternative energy source to dwindling fossil fuel reserves, as it carries the highest energy per unit mass and its combustion results in the release of water vapour as only byproduct. The facultatively anaerobic thermophile Parageobacillus thermoglucosidasius is able to produce hyd...

journal_title：AMB Express

authors： Mohr T,Aliyu H,Biebinger L,Gödert R,Hornberger A,Cowan D,de Maayer P,Neumann A

更新日期：2019-12-23 00:00:00

abstract：:Lactobacillus panis strain PM1 is an obligatory heterofermentative and aerotolerant microorganism that also produces 1,3-propanediol from glycerol. This study investigated the metabolic responses of L. panis PM1 to oxidative stress under aerobic conditions. Growth under aerobic culture triggered an early entrance of L...

journal_title：AMB Express

authors： Kang TS,Korber DR,Tanaka T

更新日期：2013-01-31 00:00:00

abstract：:Phasins are amphiphilic proteins involved in the regulation of the number and size of polyhydroxybutyrate (PHB) granules. The plant growth promoting bacterium Azospirillum brasilense Sp7 accumulates high quantities of bioplastic PHB as carbon and energy source. By analyzing the genome, we identified six genes that cod...

journal_title：AMB Express

authors： Martínez-Martínez MLA,González-Pedrajo B,Dreyfus G,Soto-Urzúa L,Martínez-Morales LJ

更新日期：2019-09-25 00:00:00

abstract：:Denitrifying anaerobic methane oxidation (damo) bioprocesses can remove nitrate using methane as the electron donor, which gains great concern due to the current stringent discharge standard of nitrogen in wastewater treatment plants. To obtain an engineering acceptable nitrogen removal rate (NRR) and demonstrate the ...

journal_title：AMB Express

authors： Li W,Lu P,Chai F,Zhang L,Han X,Zhang D

更新日期：2018-06-30 00:00:00

abstract：: Hydroquinone-1,2-dioxygenase, an enzyme involved in the degradation of alkylphenols in Sphingomonas sp. strain TTNP3 was purified to apparent homogeneity. The extradiol dioxygenase catalyzed the ring fission of hydroquinone to 4-hydroxymuconic semialdehyde and the degradation of chlorinated and several alkylated hydr...

journal_title：AMB Express

authors： Kolvenbach BA,Lenz M,Benndorf D,Rapp E,Fousek J,Vlcek C,Schäffer A,Gabriel FL,Kohler HP,Corvini PF

更新日期：2011-05-27 00:00:00

abstract：:Cellulose degrading enzymes usually have a two-domain structure consisting of a catalytic domain and a non-catalytic carbohydrate-binding module. Although it is well known the importance of those modules in cell wall degrading process, their function is not yet fully understood. Here, we analyze the cellulose-hydrolys...

journal_title：AMB Express

authors： Mello BL,Polikarpov I

更新日期：2014-04-25 00:00:00