Abstract：
:Here we determined the relative expression of HERV-K and W proviruses in HIV infected and non-infected mothers as well as their respective babies up to 1 year-old. HIV-infected mothers, their babies and uninfected control groups presented expression of both HERV-K and HERV-W with relatively high frequency. While the level of HERV-K expression was similar among groups, the level of HERV-W expression in HIV-infected mothers was four-fold higher than the uninfected mothers from the control group (p < 0.01). HERV-W was down regulated in HIV-exposed babies in comparison to non-exposed babies. To our knowledge, this is the first report of HERV transcriptional activity in babies from 0-1 year-old.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Nali LH,Oliveira AC,Alves DO,Caleiro GS,Nunes CF,Gerhardt D,Succi RC,Romano CM,Machado DMdoi
10.1007/s00705-016-3167-2subject
Has Abstractpub_date
2017-03-01 00:00:00pages
857-861issue
3eissn
0304-8608issn
1432-8798pii
10.1007/s00705-016-3167-2journal_volume
162pub_type
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