Abstract:
:Fungal infections directly affect millions of people each year. In addition to the invasive fungal infections of humans, the plants and animals that comprise our primary food source are also susceptible to diseases caused by these eukaryotic microbes. The need for antifungals, not only for our medical needs, but also for use in agriculture and livestock causes a high demand for novel antimycotics. Herein, we provide an overview of the most commonly used antifungals in medicine and agriculture. We also present a summary of the recent progress (from 2010-2016) in the discovery/development of new agents against fungal strains of medical/agricultural relevance, as well as information related to their biological activity, their mode(s) of action, and their mechanism(s) of resistance.
journal_name
Medchemcommjournal_title
MedChemCommauthors
Ngo HX,Garneau-Tsodikova S,Green KDdoi
10.1039/C6MD00222Fsubject
Has Abstractpub_date
2016-07-01 00:00:00pages
1285-1306issue
7eissn
2040-2503issn
2040-2511journal_volume
7pub_type
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