Abstract:
:A library of 33 compounds was screened for potentiation of the antibiotic FR 900098 against the Francisella tularensis surrogate Francisella novicida. From the screen a highly potent 2-oxazoline adjuvant was discovered capable of potentiating FR 900098 with a 1000-fold reduction in MIC against the Francisella sub-species F. novicida and F. philomiragia.
journal_name
Medchemcommjournal_title
MedChemCommauthors
Stephens MD,Yodsanit N,Melander Cdoi
10.1039/C6MD00365Fsubject
Has Abstractpub_date
2016-01-01 00:00:00pages
1952-1956issue
10eissn
2040-2503issn
2040-2511journal_volume
7pub_type
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