CRISPR-PCS: a powerful new approach to inducing multiple chromosome splitting in Saccharomyces cerevisiae.

abstract：:This study aimed to determine the clinicopathological features of the subtypes of ampullary carcinoma (AC) to explore the indications for endoscopic papillectomy (EP) in early AC. Fifty-seven patients with AC who underwent curative resection were retrospectively reviewed. The 0/IA stages were significantly more common...

journal_title：Scientific reports

authors： Yamamoto K,Itoi T,Nagata N,Sofuni A,Tsuchiya T,Ishii K,Tanaka R,Tonozuka R,Honjo M,Mukai S,Asai Y,Matsunami Y,Yamaguchi H,Matsubayashi J,Joyama E,Nagakawa Y

更新日期：2021-01-12 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is not sensitive to radiotherapy and chemotherapy and experiences postoperative relapse extremely easy, which is the major cause of the high mortality rate. The Notch signaling pathway is expected to become a new target for the biological treatment of HCC. We searched databases for studi...

journal_title：Scientific reports

authors： Zhang Y,Li D,Feng F,An L,Hui F,Dang D,Zhao Q

更新日期：2017-11-01 00:00:00

abstract：:Childhood and adolescent overweight and obesity are increasing in China, but limited information is available on its secular trends in Guangzhou. In this cross-sectional study, ten-wave successive data were obtained from the physical fitness surveillance for students in Guangzhou from 2003 to 2012. A total of 2,619,15...

journal_title：Scientific reports

authors： Zong Y,Xie R,Deng N,Liu L,Tan W,Gao Y,Yang J,Yang Y

更新日期：2017-09-21 00:00:00

abstract：:Application of controlled-release urea (CRU) improves crop yield and nitrogen use efficiency (NUE) compared with conventional urea. However, the effectiveness of CRU differs with fertilization placement. A two site-year field experiment was carried out in fluvo-aquic soil in central China to study the effects of two N...

journal_title：Scientific reports

authors： Liu W,Xiong Y,Xu X,Xu F,Hussain S,Xiong H,Yuan J

更新日期：2019-12-30 00:00:00

abstract：:The precise clinicopathologic significance of myeloid differentiation primary response gene (MYD88) L265P mutation in diffuse large B-cell lymphomas (DLBCLs) remains elusive. To investigate the frequency and clinicopathologic significance of the MYD88 L265P mutation in DLBCLs, we conducted a meta-analysis of 40 publis...

journal_title：Scientific reports

authors： Lee JH,Jeong H,Choi JW,Oh H,Kim YS

更新日期：2017-05-11 00:00:00

abstract：:Media reports of a celebrity's suicide may be followed by copycat suicides, and the impact may vary in different age and sex subgroups. We proposed a quantitative framework to assess the vulnerability of age and sex subgroups to copycat suicide and used this method to investigate copycat suicides in relation to the su...

journal_title：Scientific reports

authors： Yi H,Hwang J,Bae HJ,Kim N

更新日期：2019-11-21 00:00:00

abstract：:Differences in the pathogenesis and clinical characteristics between lamellar macular hole (LMH) with and without LMH-associated epiretinal proliferation (LHEP) can have surgical implications. This study investigated the effects of treating LHEP by foveolar internal limiting membrane (ILM) non-peeling and epiretinal p...

journal_title：Scientific reports

authors： Ho TC,Ho AY,Chen MS

更新日期：2019-11-05 00:00:00

abstract：:Bumblebees are exposed to pesticides applied for crop protection while foraging on treated plants, with increasing evidence suggesting that this sublethal exposure has implications for pollinator declines. The challenges of navigating and learning to manipulate many different flowers underline the critical role learni...

journal_title：Scientific reports

authors： Stanley DA,Smith KE,Raine NE

更新日期：2015-11-16 00:00:00

abstract：:The triple negative basal-like (TNBL) breast carcinoma is an aggressive and unfavorable prognosis disease. Inhibitors of poly(ADP-ribose) polymerase such as Olaparib could represent a promising targeted therapy but their sensitivity against Multidrug Resistance proteins (MDR), which causes resistance, is not well defi...

journal_title：Scientific reports

authors： Dufour R,Daumar P,Mounetou E,Aubel C,Kwiatkowski F,Abrial C,Vatoux C,Penault-Llorca F,Bamdad M

更新日期：2015-08-03 00:00:00

abstract：:Magnetic refrigeration is of great interest due to its high energy efficiency, environmental friendliness and low cost. However, undesired hysteresis losses, concentrated working temperature interval (WTI) and poor mechanical stability are vital drawbacks that hinder its practical application. Off-stoichiometric Ni-Mn...

journal_title：Scientific reports

authors： Qian M,Zhang X,Wei L,Martin P,Sun J,Geng L,Scott TB,Peng HX

更新日期：2018-11-08 00:00:00

abstract：:This study investigated lead concentrations in the hairs of radiographers working in the radiological departments of general hospitals that used lead shielding for radiation protection. We collected scalp hair samples from 32 radiographers working in four radiology departments with lead shielding and 18 administration...

journal_title：Scientific reports

authors： Hung MC,Chang P

更新日期：2021-01-08 00:00:00

abstract：:The dispersal of animals from their birth place has profound effects on the immediate survival and longer-term persistence of populations. Molecular studies have estimated that bumblebee colonies can be established many kilometers from their queens' natal nest site. However, little is known about when and how queens d...

journal_title：Scientific reports

authors： Makinson JC,Woodgate JL,Reynolds A,Capaldi EA,Perry CJ,Chittka L

更新日期：2019-03-20 00:00:00

abstract：:Angiogenesis plays a key role in several diseases including cancer, ischemic vascular disease, and Alzheimer's disease. Chemical genetic screening of endothelial tube formation provides a robust approach for identifying signalling components that impact microvascular network morphology as well as endothelial cell biol...

journal_title：Scientific reports

authors： Sailem HZ,Al Haj Zen A

更新日期：2020-08-14 00:00:00

abstract：:Communication between vascular plants through volatile organic compounds (VOCs) impacts on ecosystem functioning. However, nothing is known about that between non-vascular plants. To investigate plant-plant VOCs interaction in bryophytes we exposed rare peatland moss Hamatocaulis vernicosus to VOCs of its common compe...

journal_title：Scientific reports

authors： Vicherová E,Glinwood R,Hájek T,Šmilauer P,Ninkovic V

更新日期：2020-05-04 00:00:00

abstract：:In this report, we propose and demonstrate an air-mode photonic crystal ring resonator (PhCRR) on silicon-on-insulator platform. Air mode is utilized to confine the optical field into photonic crystal (PhC) air holes, which is confirmed by the three-dimensional finite-difference time-domain simulation. PhCRR structure...

journal_title：Scientific reports

authors： Gao G,Zhang Y,Zhang H,Wang Y,Huang Q,Xia J

更新日期：2016-01-28 00:00:00

abstract：:Post-operative atrial fibrillation (POAF) is postulated as a complex interaction of different pathogenic factors, suggesting inflammatory processes as a main trigger of this particular type of atrial fibrillation. Therefore, the study sought to assess the impact of cellular immunity on the development of POAF. Compari...

journal_title：Scientific reports

authors： Sulzgruber P,Thaler B,Koller L,Baumgartner J,Pilz A,Steininger M,Schnaubelt S,Fleck T,Laufer G,Steinlechner B,Winter MP,Goliasch G,Wojta J,Niessner A

更新日期：2018-06-25 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep20067. ...

journal_title：Scientific reports

authors： Chen H,Wang G,Simha R,Du C,Zeng C

更新日期：2017-06-30 00:00:00

abstract：:Synchrotron radiation microtomography (SRμCT) is a nominally non-destructive 3D imaging technique which can visualise the internal structures of whole soft tissues. As a multi-stage technique, the cumulative benefits of optimising sample preparation, scanning parameters and signal processing can improve SRμCT imaging ...

journal_title：Scientific reports

authors： Strotton MC,Bodey AJ,Wanelik K,Darrow MC,Medina E,Hobbs C,Rau C,Bradbury EJ

更新日期：2018-08-13 00:00:00

abstract：:Activating transcription factor 4 (ATF4) is constitutively expressed in a variety of tissues, and regulates several pathological features associated with metabolic diseases such as non-alcoholic fatty liver diseases (NAFLD) and obesity. However, the role of ATF4 in animal model systems is poorly understood. To investi...

journal_title：Scientific reports

authors： Yeh KY,Lai CY,Lin CY,Hsu CC,Lo CP,Her GM

更新日期：2017-11-27 00:00:00

abstract：:Human induced pluripotent stem cells (hiPSCs) show great promise for obesity treatment as they represent an unlimited source of brown/brite adipose progenitors (BAPs). However, hiPSC-BAPs display a low adipogenic capacity compared to adult-BAPs when maintained in a traditional adipogenic cocktail. The reasons of this ...

journal_title：Scientific reports

authors： Hafner AL,Contet J,Ravaud C,Yao X,Villageois P,Suknuntha K,Annab K,Peraldi P,Binetruy B,Slukvin II,Ladoux A,Dani C

更新日期：2016-08-31 00:00:00

abstract：:Although the growth of graphene by chemical vapor deposition is a production technique that guarantees high crystallinity and superior electronic properties on large areas, it is still a challenge for manufacturers to efficiently scale up the production to the industrial scale. In this context, issues related to the p...

journal_title：Scientific reports

authors： Lisi N,Dikonimos T,Buonocore F,Pittori M,Mazzaro R,Rizzoli R,Marras S,Capasso A

更新日期：2017-08-30 00:00:00

abstract：:Changes in the stability, hydrogen diffusion, and mechanical properties of the NbH phases from Ni-doping was studied by using first-principles methods. The calculation results reveal that the single H atom adsorption is energetically favorable at the tetrahedral interstitial site (TIS) and octahedral interstitial site...

journal_title：Scientific reports

authors： Wu Y,Wang Z,Wang D,Wan Z,Zhong Y,Hu C,Zhou H

更新日期：2017-07-26 00:00:00

abstract：:Huntington's disease (HD) is caused by CAG repeat expansion in the huntingtin gene. The expanded polyglutamine (polyQ) repeat of the encoded protein leads to protein misfolding and aggregation, resulting in increased neuronal cell death. DNAJ co-chaperones play a crucial role in transferring misfolded/unfolded protein...

journal_title：Scientific reports

authors： Rodríguez-González C,Lin S,Arkan S,Hansen C

更新日期：2020-05-18 00:00:00

abstract：:The combined effects of cervical electrical stimulation alone or in combination with the monoaminergic agonist buspirone on upper limb motor function were determined in six subjects with motor complete (AIS B) injury at C5 or above and more than one year from time of injury. Voluntary upper limb function was evaluated...

journal_title：Scientific reports

authors： Freyvert Y,Yong NA,Morikawa E,Zdunowski S,Sarino ME,Gerasimenko Y,Edgerton VR,Lu DC

更新日期：2018-10-19 00:00:00

abstract：:Leukotriene E4 (LTE4) the most stable of the cysteinyl leukotrienes (cysLTs) binds poorly to classical type 1 (CysLT1) and 2 (CysLT2) receptors although it induces potent responses in human airways in vivo, such as bronchoconstriction, airway hyperresponsiveness and inflammatory cell influx suggesting the presence of ...

journal_title：Scientific reports

authors： Foster HR,Fuerst E,Branchett W,Lee TH,Cousins DJ,Woszczek G

更新日期：2016-02-02 00:00:00

abstract：:During inflammatory response, blood leukocytes adhere to the endothelium. This process involves numerous adhesion molecules, including a transmembrane chemokine, CX3CL1, which behaves as a molecular cluster. How this cluster assembles and whether this association has a functional role remain unknown. The analysis of C...

journal_title：Scientific reports

authors： Ostuni MA,Hermand P,Saindoy E,Guillou N,Guellec J,Coens A,Hattab C,Desuzinges-Mandon E,Jawhari A,Iatmanen-Harbi S,Lequin O,Fuchs P,Lacapere JJ,Combadière C,Pincet F,Deterre P

更新日期：2020-06-03 00:00:00

abstract：:In the last decade, extracellular vesicles (EVs) have become a hot topic. The findings on EVs content and effects have made them a major field of interest in cancer research. EVs, are able to be internalized through integrins expressed in parental cells, in a tissue specific manner, as a key step of cancer progression...

journal_title：Scientific reports

authors： Reclusa P,Verstraelen P,Taverna S,Gunasekaran M,Pucci M,Pintelon I,Claes N,de Miguel-Pérez D,Alessandro R,Bals S,Kaushal S,Rolfo C

更新日期：2020-04-16 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Pizato N,Luzete BC,Kiffer LFMV,Corrêa LH,Santos IO,Assumpção JAF,Ito MK,Magalhães KG

更新日期：2018-06-22 00:00:00

abstract：:Non-arteritic anterior ischemic optic neuropathy (NAION) causes a sudden loss of vision and lacks effective treatment. Granulocyte colony-stimulating factor (G-CSF) provides neuroprotection against the experimental optic nerve injuries but also induce leukocytosis upon typical administration. We found synergetic neuro...

journal_title：Scientific reports

authors： Liu PK,Wen YT,Lin W,Kapupara K,Tai M,Tsai RK

更新日期：2020-06-25 00:00:00

abstract：:The role of soil organic carbon in global carbon cycles is receiving increasing attention both as a potentially large and uncertain source of CO2 emissions in response to predicted global temperature rises, and as a natural sink for carbon able to reduce atmospheric CO2. There is general agreement that the technical p...

journal_title：Scientific reports

authors： Zomer RJ,Bossio DA,Sommer R,Verchot LV

更新日期：2017-11-14 00:00:00