Abstract:
:Microsaccades aid vision by helping to strategically sample visual scenes. Despite the importance of these small eye movements, no cortical area has ever been implicated in their generation. Here, we used unilateral and bilateral reversible inactivation of the frontal eye fields (FEF) to identify a cortical drive for microsaccades. Unexpectedly, FEF inactivation altered microsaccade metrics and kinematics. Such inactivation also impaired microsaccade deployment following peripheral cue onset, regardless of cue side or inactivation configuration. Our results demonstrate that the FEF provides critical top-down drive for microsaccade generation, particularly during the recovery of microsaccades after disruption by sensory transients. Our results constitute the first direct evidence, to our knowledge, for the contribution of any cortical area to microsaccade generation, and they provide a possible substrate for how cognitive processes can influence the strategic deployment of microsaccades.
journal_name
PLoS Bioljournal_title
PLoS biologyauthors
Peel TR,Hafed ZM,Dash S,Lomber SG,Corneil BDdoi
10.1371/journal.pbio.1002531subject
Has Abstractpub_date
2016-08-10 00:00:00pages
e1002531issue
8eissn
1544-9173issn
1545-7885pii
PBIOLOGY-D-16-00450journal_volume
14pub_type
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