Secretory locations of SIPC in Amphibalanus amphitrite cyprids and a novel function of SIPC in biomineralization.

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Jikomes N,Zoorob M

更新日期：2020-08-27 00:00:00

abstract：:Inertial and deformability- based particles separations gradually attract more significant attentions. In this work, we present a hybrid chip by combining the advantages of inertial and deformability -based principle. The chip is a triplet parallelizing spiral inertial microfluidic chip interconnected with numerable t...

journal_title：Scientific reports

authors： Chen H

更新日期：2018-03-06 00:00:00

abstract：:Prostate cancer (PCa) is the second most common cancer among men worldwide. Its etiology remains largely unknown compared to other common cancers. We have developed a risk stratification model combining environmental factors with family history and genetic susceptibility. 818 PCa cases and 1,006 healthy controls were ...

journal_title：Scientific reports

authors： Gómez-Acebo I,Dierssen-Sotos T,Fernandez-Navarro P,Palazuelos C,Moreno V,Aragonés N,Castaño-Vinyals G,Jiménez-Monleón JJ,Ruiz-Cerdá JL,Pérez-Gómez B,Ruiz-Dominguez JM,Molero JA,Pollán M,Kogevinas M,Llorca J

更新日期：2017-08-21 00:00:00

abstract：:The temporal correspondence between two arbitrarily chosen pairs of alternating features can generally be reported for rates up to 3-4 Hz. This limit is however surpassed for specialised visual mechanisms that encode conjunctions of features. Here we show that this 3-4 Hz limit is exceeded for eye gaze and eyebrow pai...

journal_title：Scientific reports

authors： Harrison C,Binetti N,Mareschal I,Johnston A

更新日期：2018-06-13 00:00:00

abstract：:Bronchospasm compresses the bronchial epithelium, and this compressive stress has been implicated in asthma pathogenesis. However, the molecular mechanisms by which this compressive stress alters pathways relevant to disease are not well understood. Using air-liquid interface cultures of primary human bronchial epithe...

journal_title：Scientific reports

authors： Kılıç A,Ameli A,Park JA,Kho AT,Tantisira K,Santolini M,Cheng F,Mitchel JA,McGill M,O'Sullivan MJ,De Marzio M,Sharma A,Randell SH,Drazen JM,Fredberg JJ,Weiss ST

更新日期：2020-01-22 00:00:00

abstract：:Release of pro-inflammatory mediators by mast cells is a key feature of allergic disease. The 'dogma' is that IgE molecules merely sensitise mast cells by binding FcεRI prior to cross-linking by multivalent allergen, receptor aggregation and mast cell activation. However, certain monoclonal IgE antibodies have been sh...

journal_title：Scientific reports

authors： Bax HJ,Bowen H,Dodev TS,Sutton BJ,Gould HJ

更新日期：2015-04-20 00:00:00

abstract：:The implementation of HTS (high-throughput sequencing) approaches is rapidly changing our understanding of the lichen symbiosis, by uncovering high bacterial and fungal diversity, which is often host-specific. Recently, HTS methods revealed the presence of multiple photobionts inside a single thallus in several lichen...

journal_title：Scientific reports

authors： Paul F,Otte J,Schmitt I,Dal Grande F

更新日期：2018-06-05 00:00:00

abstract：:The entire recrystallisation sequence and associated crystallographic texture evolution of Mg-0.8Zn-0.2Ca (wt.%) alloy was tracked using a quasi-in-situ electron backscatter diffraction (EBSD) method. Characteristic "Rare Earth" (RE) texture was formed, originating mainly from double twins and twinning-related shear b...

journal_title：Scientific reports

authors： Guan D,Liu X,Gao J,Ma L,Wynne BP,Rainforth WM

更新日期：2019-05-09 00:00:00

abstract：:Helicobacter pylori (H. pylori ) infection is a major cause of chronic gastritis and is highly related to duodenal ulcer (DU) and gastric cancer (GC). To identify H. pylori-related GC biomarkers with high seropositivity in GC patients, differences in levels of protein expression between H. pylori from GC and DU patien...

journal_title：Scientific reports

authors： Su YL,Huang HL,Huang BS,Chen PC,Chen CS,Wang HL,Lin PH,Chieh MS,Wu JJ,Yang JC,Chow LP

更新日期：2016-11-07 00:00:00

abstract：:Varroa destructor mites express strong avoidance of the Apis cerana worker brood in the field. The molecular mechanism for this phenomenon remains unknown. We identified a Varroa toxic protein (VTP), which exhibited toxic activity toward A. cerana worker larvae, in the saliva of these mites, and expressed VTP in an Es...

journal_title：Scientific reports

authors： Zhang Y,Han R

更新日期：2018-02-21 00:00:00

abstract：:Chronic inflammatory insults compromise immune cell responses and ultimately contribute to pathologic outcomes. Clinically, it has been suggested that bone debris and implant particles, such as polymethylmethacrylate (PMMA), which are persistently released following implant surgery evoke heightened immune, inflammator...

journal_title：Scientific reports

authors： Chen TH,Arra M,Mbalaviele G,Swarnkar G,Abu-Amer Y

更新日期：2019-07-18 00:00:00

abstract：:Immune parameters show characteristic normal baseline levels and variance in the population. We characterised the degree of inter-individual and within-individual variation over one-year time period in 33 immune cell subsets by flow cytometry in peripheral blood mononuclear cells from 43 healthy young adult volunteers...

journal_title：Scientific reports

authors： Kanodia P,Kaur G,Coshic P,Chatterjee K,Neeman T,George A,Rath S,Bal V,Prabhu SB

更新日期：2019-10-14 00:00:00

abstract：:The exopeptidases of family S46 are exceptional, as the closest homologs of these enzymes are the endopeptidases of clan PA. The three-dimensional structure of S46 enzymes is unknown and only one of the catalytic residues, the serine, has been identified. The catalytic histidine and aspartate residues are not experime...

journal_title：Scientific reports

authors： Suzuki Y,Sakamoto Y,Tanaka N,Okada H,Morikawa Y,Ogasawara W

更新日期：2014-03-06 00:00:00

abstract：:Working memory (WM) impairments in ADHD have been consistently reported along with deficits in attentional control. Yet, it is not clear which specific WM processes are affected in this condition. A deficient coupling between attention and WM has been reported. Nevertheless, most studies focus on the capacity to retai...

journal_title：Scientific reports

authors： Ortega R,López V,Carrasco X,Escobar MJ,García AM,Parra MA,Aboitiz F

更新日期：2020-05-08 00:00:00

abstract：:Gallbladder cancer (GBC) is the most common malignant tumor of the biliary system. However, the mechanisms underlying its tumor initiation, progression, and metastasis are not yet fully understood. The annexin A4 (ANXA4) gene is highly expressed in GBC tissues and may play an important role in the initiation and progr...

journal_title：Scientific reports

authors： Yao HS,Sun C,Li XX,Wang Y,Jin KZ,Zhang XP,Hu ZQ

更新日期：2016-08-05 00:00:00

abstract：:Neuroinflammation and accompanying microglial dysfunction are now appreciated to be involved in Alzheimer's disease (AD) pathogenesis. Critical to the process of neuroinflammation are the type-I interferon (IFN) family of cytokines. Efforts to phenotypically characterize microglia within AD identify distinct populatio...

journal_title：Scientific reports

authors： Moore Z,Mobilio F,Walker FR,Taylor JM,Crack PJ

更新日期：2020-02-21 00:00:00

abstract：:Multidomain proteins account for 70% of the eukaryotic proteome. In genetic disease, multidomain proteins are often affected by numerous mutations, but the effects of these mutations on protein stability and their roles in genetic disease are not well understood. Here, we analyzed protein globular domains to understan...

journal_title：Scientific reports

authors： Ortiz FW,Sergeev YV

更新日期：2019-03-06 00:00:00

abstract：:The possibility of producing transgenic cloned buffalos by nuclear transfer of fetal fibroblasts expressing enhanced green fluorescent protein (EGFP) was explored in this study. When buffalo fetal fibroblasts (BFFs) isolated from a male buffalo fetus were transfected with pEGFP-N1 (EGFP is driven by CMV and Neo is dri...

journal_title：Scientific reports

authors： Lu F,Luo C,Li N,Liu Q,Wei Y,Deng H,Wang X,Li X,Jiang J,Deng Y,Shi D

更新日期：2018-05-03 00:00:00

abstract：:From the 1950s, the Po delta, one of the largest anthropogenic world deltas, has been subjected to a fast degradation and shoreline retreat due a marked reduction of sediment supply, mainly controlled by human impacts/factors, including subsidence. Through the interpretation of satellite images, coupled with the analy...

journal_title：Scientific reports

authors： Ninfo A,Ciavola P,Billi P

更新日期：2018-02-22 00:00:00

abstract：:Respiratory tract infections (RTIs) are common among Hajj pilgrims, but risk factors for RTIs and respiratory pathogen acquisition during the Hajj are not clearly identified. Based on previous studies, most frequent pathogens acquired by Hajj pilgrims were investigated: rhinovirus, human coronaviruses, influenza virus...

journal_title：Scientific reports

authors： Hoang VT,Ali-Salem S,Belhouchat K,Meftah M,Sow D,Dao TL,Ly TDA,Drali T,Ninove L,Yezli S,Alotaibi B,Raoult D,Parola P,Pommier de Santi V,Gautret P

更新日期：2019-11-28 00:00:00

abstract：:PARP inhibitors have shown remarkable efficacy in the clinical management of several BRCA-mutated tumors. This approach is based on the long-standing hypothesis that PARP inhibition will impair the repair of single stranded breaks, causing synthetic lethality in tumors with loss of high-fidelity double-strand break ho...

journal_title：Scientific reports

authors： Principe DR,Narbutis M,Koch R,Rana A

更新日期：2020-11-19 00:00:00

abstract：:Identifying the occurrence mechanism of drug-induced side effects (SEs) is critical for design of drug target and new drug development. The expression of genes in biological processes is regulated by transcription factors(TFs) and/or microRNAs. Most of previous studies were focused on a single level of gene or gene se...

journal_title：Scientific reports

authors： Jia X,Jin Q,Liu X,Bian X,Wang Y,Liu L,Ma H,Tan F,Gu M,Chen X

更新日期：2017-07-20 00:00:00

abstract：:Jasmonates (JAs) are plant-specific key signaling molecules that respond to various stimuli and are involved in the synthesis of secondary metabolites. However, little is known about the JA signal pathway, especially in economically significant medicinal plants. To determine the functions of novel genes that participa...

journal_title：Scientific reports

authors： Ge Q,Zhang Y,Hua WP,Wu YC,Jin XX,Song SH,Wang ZZ

更新日期：2015-09-21 00:00:00

abstract：:The aim of the present study was to evaluate sleep and mood disorders in patients with irritating ocular diseases. The study design was a cross-sectional/case-control study conducted in six eye clinics. Out of 715 outpatients diagnosed with irritating ocular surface diseases and initially enrolled, 301 patients with d...

journal_title：Scientific reports

authors： Ayaki M,Kawashima M,Negishi K,Kishimoto T,Mimura M,Tsubota K

更新日期：2016-03-01 00:00:00

abstract：:Nano/microfibrous structure can induce high cellular activities because of the topological similarity of the extracellular matrix, and thus, are widely used in various tissue regenerative materials. However, the fabrication of a bioceramic (high weight percent)-based 3D microfibrous structure is extremely difficult be...

journal_title：Scientific reports

authors： Kim M,Yun HS,Kim GH

更新日期：2017-06-09 00:00:00

abstract：:The non-enzymatic browning, namely Maillard reaction is commonly invoked to account for abiotic chemical transformations of organic matter. Here we report a new reaction pathway via the Maillard reaction to systematically synthesize a series of nitrogen-doped carbon dots (C-dots) with superhigh quantum yield (QY) and ...

journal_title：Scientific reports

authors： Wei W,Xu C,Wu L,Wang J,Ren J,Qu X

更新日期：2014-01-06 00:00:00

abstract：:Celiac disease (CeD) is a multifactorial disease influenced by both genetic and environmental risk factors. CeD genetic components are mainly due to HLA class II genes, which account for approximately 40% of the disease heritability. The environmental factor is linked to gliadin ingestion. Despite genetic and epigenet...

journal_title：Scientific reports

authors： Auricchio R,Galatola M,Cielo D,Amoresano A,Caterino M,De Vita E,Illiano A,Troncone R,Greco L,Ruoppolo M

更新日期：2019-10-04 00:00:00

abstract：:The present study aimed to evaluate the efficiency, effectiveness, and biocompatibility of two agents used for the chemomechanical removal of carious dentin. Sixty extracted carious human teeth were treated with a conventional bur (CBG) or chemomechanical agents - Papacarie Duo (PG) and Brix 3000 (BG). Treatment effic...

journal_title：Scientific reports

authors： Santos TML,Bresciani E,Matos FS,Camargo SEA,Hidalgo APT,Rivera LML,Bernardino ÍM,Paranhos LR

更新日期：2020-05-15 00:00:00

abstract：:Diabetic nephropathy, the major cause of chronic kidney disease, is associated with progressive renal fibrosis. Recently, accumulation of periostin, an extracellular matrix protein, was shown to augment renal fibrosis. Aptamers have higher binding affinities without developing the common side effects of antibodies. Th...

journal_title：Scientific reports

authors： Um JE,Park JT,Nam BY,Lee JP,Jung JH,Kim Y,Kim S,Park J,Wu M,Han SH,Yoo TH,Kang SW

更新日期：2017-08-17 00:00:00

abstract：:Joubert syndrome (JS) is an inherited ciliopathy characterized by a distinctive cerebellar and brain stem malformation which is known as the "molar tooth sign" on axial brain images, hypotonia, and developmental delay. Approximately 25-30% of patients with JS have kidney disease and many of them progress to end-stage ...

journal_title：Scientific reports

authors： Takagi Y,Miura K,Yabuuchi T,Kaneko N,Ishizuka K,Takei M,Yajima C,Ikeuchi Y,Kobayashi Y,Takizawa T,Hisano M,Tsurusaki Y,Matsumoto N,Hattori M

更新日期：2021-01-11 00:00:00