Abstract:
OBJECTIVES:To compare iodine content (IC) of solitary lung cancer using dynamic measurements of CT attenuation (Hounsfield Units, HU) and to correlate their quantitative CT data with expressions of vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR) and hypoxia-inducible factor-1α (HIF-1α) using immunostaining methods. METHODS:This study included 18 patients with adenocarcinoma, who undergone dual energy dynamic multiphase CT to examine solitary lung nodules (6 part-solid and 12 solid nodules). Tumor size was 21.1 mm±8.1 (9-39mm) [Mean±SD (range)]. Contrast volume was determined by weight (2ml/kg). Contrast volume and injection rate were 110.5 ml±17.2 (80-144ml) and 1.84ml/s±0.30 (1.3-2.4ml/s), respectively. Enhancement values ([CT value at each delayed scan-CT value at unenhanced scan]) and net enhancement values ([peak CT value-CT value at unenhanced scan]) were calculated in HU from 65keV monochromatic image. IC at each delayed scan was measured in mg/cm(3) from the iodine-water material decomposition pair on the advantage workstation VolumeShare4. Immunostaining using VEGF, EGFR, and HIF-1α was performed by two pathologists, who evaluated the expression level of them subjectively. Statistical analyses were performed with rank correlation tests and regression analysis. RESULTS:IC at 2- and 3-minute delayed scan (x) and immunostaining score of HIF-1α (y) showed a significantly positive correlation (r=0.64 and 0.52, p=0.004 and 0.03): regression equation, y=1.34+0.58x and y=1.51+0.55x, respectively. CONCLUSIONS:Dual-energy dynamic multiphase CT can measure iodine content in lung adenocarcinoma. Iodine content at 2- and 3-minute delayed scan might correlate with the expression level of HIF-1α.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Yanagawa M,Morii E,Hata A,Fujiwara M,Gyobu T,Ueda K,Honda O,Tomiyama Ndoi
10.1016/j.ejrad.2016.05.016subject
Has Abstractpub_date
2016-08-01 00:00:00pages
1407-13issue
8eissn
0720-048Xissn
1872-7727pii
S0720-048X(16)30168-1journal_volume
85pub_type
杂志文章abstract::A 70-year-old male was admitted to hospital for a liver tumor. We diagnosed that hepatocellular carcinoma (HCC), 1.5 cm in diameter, by several examinations. We performed ultrasonically guided radio-frequency ablation (RFA). Ultrasonography (US) 9 days post-therapy revealed a cystic lesion 1.5 cm in diameter. Color Do...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(01)00436-3
更新日期:2002-10-01 00:00:00
abstract:AIM:To evaluate the author's experience with the use of diffusion tensor magnetic resonance imaging (DTI) on patients with glial tumors. METHODS:A retrospective evaluation of a group of 24 patients with glial tumors was performed. There were eight patients with Grade II, eight patients with Grade III and eight patient...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.03.030
更新日期:2010-06-01 00:00:00
abstract:INTRODUCTION:To describe serial changes in irradiated superior cervical sympathetic ganglia (SCSGs) on MRI (magnetic resonance imaging) evaluation in patients with head and neck squamous cell carcinoma (HNSCC) and to find the features differentiating them from the metastatic retropharyngeal lymph nodes. MATERIALS AND ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2017.11.008
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:We hypothesized that bone SPECT combined with multiplanar reconstructed CT can identify and target the pain-inducing focus in the foot and can be used to successfully guide anaesthetic infiltrations. Therefore we prospectively investigated feasibility and predictive value of bone SPECT/CT for image guided diagn...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2010.09.013
更新日期:2011-12-01 00:00:00
abstract::The management of patients with spinal trauma is based on the following goals: (1) the preservation of life; (2) preserving and maximising the neurological function; and (3) providing a stable, painless vertebral column. There have been advances in both non operative as well operative modalities of treatment of patien...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/s0720-048x(02)00045-1
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVE:To determine if concomitant CT-guided biopsy and percutaneous fiducial seed placement in the lung can be performed in a selective patient population without increased complication or decreased success rates compared to either procedure alone. MATERIALS AND METHODS:An IRB approved retrospective analysis of 28...
journal_title:European journal of radiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ejrad.2014.01.006
更新日期:2014-04-01 00:00:00
abstract::We report a case of giant, benign renal cyst that was treated with percutaneous aspiration and sclerotherapy using 95% alcohol. A seven French catheter was inserted into the cyst under ultrasonographic and fluoroscopic guidance, and was then left in place to drain the cyst contents. Approximately 4 l of fluid was drai...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(01)00280-7
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:This study aims to demonstrate pulmonary alterations (PA) in patients with Behcet's disease by using CT. MATERIALS AND METHODS:CTs of 50 patients with Behcet's disease and 20 others in a control group have been evaluated retrospectively for PA (septal, reticular, nodular, atelectatic opacities). RESULTS:Eight...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.01.049
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:To evaluate the correlation between quantitative dual energy CT and perfusion CT measurements in rabbit VX2 liver tumors. MATERIALS AND METHODS:This study was approved by the institutional animal care and use committee at our institution. Nine rabbits with VX2 liver tumors underwent contrast-enhanced dual ener...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.06.057
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Maintenance of mucosal healing is a primary goal when treating Crohn's disease (CD). Endoscopy is the most precise method for the assessment of mucosal healing, but is considered overly invasive for patients with CD. In contrast, CT enterography (CTE) is less invasive, but little is known about the correlati...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2016.10.022
更新日期:2017-04-01 00:00:00
abstract::The traditional standard therapy for descending thoracic aortic aneurysm (TAA) is open operative repair with graft replacement of the diseased aortic segment. Despite important advances in surgical techniques, anesthetic management, and post-operative care over the last 30 years, the mortality and morbidity of surgery...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(01)00341-2
更新日期:2001-07-01 00:00:00
abstract:INTRODUCTION:This study aims to evaluate "in vivo" the integrity of the normal-appearing spinal cord in patients with neuromyelitis optica (NMO), using diffusion tensor MR imaging, comparing to controls and patients with multiple sclerosis (MS). MATERIALS AND METHODS:We studied 8 patients with NMO and 17 without any n...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.11.026
更新日期:2012-10-01 00:00:00
abstract::The aim of the present study was to review the magnetic resonance (MR) appearance of primary epithelial cysts in order to distinguish the cysts from other possible lesions. MR images were obtained in 27 cases of epithelial cysts, including 7 odontogenic keratocysts, 3 dentigerous cysts, 1 glandular odontogenic cyst, 1...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/S0720-048X(02)00218-8
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVE:To investigate dynamic susceptibility contrast (DSC) perfusion weighted imaging (PWI) in white matter lesions (WML) in patients with multiple sclerosis (MS), using automatically generated binary masks of brain tissue. BACKGROUND:WML in MS have in some studies demonstrated perfusion abnormalities compared to ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2015.09.007
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:Breasts with malignant tumors can demonstrate a general increased vascularity compared to the contralateral breast and a prominent blood vessel adjacent to the tumor on magnetic resonance imaging (MRI). The aim of the study was to further characterize these alterations in blood supply by location of the tumor...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.10.020
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To compare qualitative and quantitative magnetic resonance (MR) imaging characteristics of hepatic hemangiomas in patients with normal, fibrotic and cirrhotic livers. MATERIALS AND METHODS:Retrospective, institutional review board approved study (waiver of informed consent). Eighty-nine consecutive patients wi...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2015.01.016
更新日期:2015-05-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the computed tomography (CT) features of 2-5 cm gastric gastrointestinal stromal tumors (GISTs), schwannomas and leimyomas which have close relationship with malignancy evaluation and differential diagnosis. METHOD:Seventy-six patients with pathologically confirmed ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2019.108783
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to test whether dual functional gold nano-shelled microcapsules (GNS-MCs) can be used as an ultrasound imaging enhancer and as an optical absorber for photothermal therapy (PTT) in a rodent model of breast cancer. METHODS:GNS-MCs were fabricated with an inner air and outer gold...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2013.09.010
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:We investigated whether the prerequisite of the maximum slope and deconvolution methods are satisfied in pancreatic perfusion CT and whether the measured parameters between these algorithms are correlated. METHODS:We examined nine beagles injected with iohexol (200 mgI kg(-1)) at 5.0 ml s(-1). The abdominal ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.06.016
更新日期:2011-01-01 00:00:00
abstract::Two-view baseline screening mammograms (oblique and cranial views) of 303 women recalled for further studies from among 7,245 women screened were reviewed by four experienced radiologists separately to evaluate the importance of the number of views taken for screening. As compared with the oblique view only, two views...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::Apoptosis plays an important role in cancer. Mechanisms hindering its action are implicated in a number of malignancies. Also, the induction of apoptosis plays a pivotal role in non-surgical cancer treatment regimes such as irradiation, chemotherapy, or hormones. Recent advanced in imaging science have made it now pos...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2005.03.016
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:To study the correlation between the T2 relaxation times of the patellar cartilage and morphological MRI findings of chondromalacia. METHODS:This prospective study comprises 50 patients, 27 men and 23 women suffering of anterior knee pain (mean age: 29.7, SD 8.3 years; range: 16-45 years). MRI of 97 knees we...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.03.007
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:This is the first ever study on the planning of the supply and demand for radiographers in Lithuania. The aim of this study was to analyze the supply and demand for radiographers in the labor market with respect to their number, structure, and services, and to provide a prognosis for the period of 2012-2030....
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.04.009
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:To enhance the accurate prediction of the response to neoadjuvant chemotherapy (NAC) in breast cancer patients by using a quantitative analysis of dynamic enhancement magnetic resonance imaging (DCE-MRI). MATERIALS AND METHODS:A dataset of 57 cancer patients with breast DCE-MR images acquired before NAC was...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2017.06.019
更新日期:2017-09-01 00:00:00
abstract::Image workstations will be the 'window' to the complex infrastructure of a PACS with its intertwined image modalities (image sources, image data bases and image processing devices) and data processing modalities (patient data bases, departmental and hospital information systems). They will serve for user-to-system dia...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(90)90146-3
更新日期:1990-05-01 00:00:00
abstract:PURPOSE:This survey was conducted to evaluate the radiation dose delivered to the patients through different CT procedures along with its corresponding risks in Yazd province. METHOD:Data for the five most common procedures were collected from six institutions from September 2017. The effective dose for each patient w...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.108932
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To retrospectively evaluate interobserver variability between breast radiologists when describing abnormal enhancement on breast MR examinations and assigning a BI-RADS category using the Breast Imaging Reporting and Data System (BI-RADS) terminology. MATERIALS AND METHODS:Five breast radiologists blinded to p...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.10.003
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To compare 64-multi-slice-CT angiography (64-MSCTA) to color-coded duplex sonography (CCDS) in the follow-up after carotid artery stenting (CAS). METHODS:Thirty patients who had an MSCTA and CCDS examination prior and after CAS were included. Twelve closed-cell and 24 open-cell stents were implanted. Neointima...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.12.007
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To develop externally validated, reproducible, and generalizable models for distinguishing three major subtypes of renal cell carcinomas (RCCs) using machine learning-based quantitative computed tomography (CT) texture analysis (qCT-TA). MATERIALS AND METHODS:Sixty-eight RCCs were included in this retrospect...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.08.014
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:To study whether calcifications in breast arteries, as seen on mammograms, predict future development of coronary artery calcifications. METHODS:We studied 499 women, aged 49-70 years, participating in a breast cancer screening program and investigated whether arterial calcifications in the breast (BAC) are ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.02.009
更新日期:2007-09-01 00:00:00