Effect of equilibration times, freezing, and thawing rates on post-thaw quality of buffalo (Bubalus bubalis) bull spermatozoa.

abstract：:Sperm DNA fragmentation varies between individuals and is more pronounced with increased patient age and time after sperm donation. The intensification of DNA fragmentation depends on the balance of the oxidoreductive system, which is regulated mainly by two enzymes - superoxide dismutase (SOD) and catalase. The objec...

journal_title：Andrology

authors： Wdowiak A,Bakalczuk S,Bakalczuk G

更新日期：2015-07-01 00:00:00

abstract：:Testosterone (T) deficiency, sexual dysfunction, obesity and obstructive sleep apnea (OSA) are common and often coexist. T prescriptions have increased worldwide during the last decade, including to those with undiagnosed or untreated OSA. The effect of T administration on sexual function, neurocognitive performance a...

journal_title：Andrology

authors： Melehan KL,Hoyos CM,Yee BJ,Wong KK,Buchanan PR,Grunstein RR,Liu PY

更新日期：2016-01-01 00:00:00

abstract：:Existing literature suggests evidence that protamine deficiency is related to DNA damage and male fertility. In this meta-analysis, we analyzed the relationship between the ratio of protamine-1 and protamine-2 with male fertility and the association of protamine deficiency with sperm DNA damage. Quality of available c...

journal_title：Andrology

authors： Ni K,Spiess AN,Schuppe HC,Steger K

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The existing classifications of varicocoeles have poor predictive value regarding the effects of surgery on sperm count. OBJECTIVE:To develop a new grading system for varicocoeles, useful as an indication for surgery. MATERIALS AND METHODS:This is a three-center prospective study which examined 173 men hav...

journal_title：Andrology

authors： Cavallini G,Scroppo FI,Colpi GM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Men with congenital unilateral absence of vas deferens were reported to be mainly azoospermic, with both unilateral renal absence and mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) but some have neither. OBJECTIVES:To assess whether in infertile couples the male partners with co...

journal_title：Andrology

authors： Mieusset R,Bieth E,Daudin M,Isus F,Delaunay B,Bujan L,Monteil L,Fauquet I,Huyghe E,Hamdi SM

更新日期：2020-05-01 00:00:00

abstract：:Fibroblast growth factors (FGFs) and their receptors (FGFRs) regulate several functions of somatic cells. In a previous work, we reported FGFR expression in human spermatozoa and their involvement in motility. This study aimed to evaluate the presence and localization of fibroblast growth factor 2 (FGF2) in human sper...

journal_title：Andrology

authors： Garbarino Azúa DJ,Saucedo L,Giordana S,Magri ML,Buffone MG,Neuspiller F,Vazquez-Levin MH,Marín-Briggiler CI

更新日期：2017-09-01 00:00:00

abstract：:Most of the non-obstructive azoospermia (NOA)-patients have only focal spermatogenesis which results in insufficient numbers of spermatozoa to reach the ejaculate. In ≈50% of these NOA-patients testicular sperm extraction (TESE) is successful and intracytoplasmic sperm injection (ICSI) is pursued. We studied whether (...

journal_title：Andrology

authors： Hessel M,de Vries M,D'Hauwers KW,Fleischer K,Hulsbergen-van de Kaa CA,Braat DD,Ramos L

更新日期：2015-05-01 00:00:00

abstract：:Urethral stricture disease, pelvic fracture urethral injury (PFUI), and their various treatment options are associated with erectile dysfunction (ED). The etiology of urethral stricture disease is multifactorial and includes trauma, inflammatory, and iatrogenic causes. Posterior urethral injuries are commonly associat...

journal_title：Andrology

authors： Sangkum P,Levy J,Yafi FA,Hellstrom WJ

更新日期：2015-05-01 00:00:00

abstract：:Spermiogenesis is the final phase of spermatogenesis. During this process, haploid round spermatids differentiate into spermatozoa, with dramatic morphological changes, including elongation and condensation of the nuclei, and formation of the flagella. Meig1 is one of many genes involved in the regulation of this proc...

journal_title：Andrology

authors： Shi Y,Zhang L,Song S,Teves ME,Li H,Wang Z,Hess RA,Jiang G,Zhang Z

更新日期：2013-05-01 00:00:00

abstract：:Smoking is strongly associated with abnormalities in histone-to-protamine transition and with alteration of protamine expression in human spermatozoa. A proper protamine to histone ratio is, however, essential for sperm chromatin maturity and DNA integrity. Alterations in these sperm nuclear proteins were observed in ...

journal_title：Andrology

authors： Hamad MF,Shelko N,Kartarius S,Montenarh M,Hammadeh ME

更新日期：2014-09-01 00:00:00

abstract：:In cryptorchid boys, failures in germ cell development have been clearly established. Some studies reported some abnormalities in Sertoli cells morphology but the results regarding their endocrine secretion remain controversial. To compare testicular hormone levels in young boys with and without cryptorchidism, we per...

journal_title：Andrology

authors： Hamdi SM,Almont T,Galinier P,Mieusset R,Thonneau P

更新日期：2017-07-01 00:00:00

abstract：:Escherichia coli (E. coli) is a common pathogen in epididymitis, which represents a prevalent entity in male reproductive tract infections (RTI). Although current treatment regimens using antibiotics are satisfactory, development of antimicrobial resistance by the pathogen represents a challenge in the management of R...

journal_title：Andrology

authors： Biswas B,Bhushan S,Rajesh A,Suraj SK,Lu Y,Meinhardt A,Yenugu S

更新日期：2015-03-01 00:00:00

abstract：:Prevalence and risk factors of concomitant primary low sexual desire/interest (LSD/I) and subsequent new-onset erectile dysfunction (ED) in men have been only partially investigated. We looked at the sociodemographic and clinical predictors of the concomitant condition of primary LSD/I - defined as the reduction in th...

journal_title：Andrology

authors： Salonia A,Clementi MC,Ventimiglia E,Colicchia M,Capogrosso P,Castiglione F,Castagna G,Boeri L,Suardi N,Cantiello F,Damiano R,Montorsi F

更新日期：2014-09-01 00:00:00

abstract：:The double sex and mab-3-related transcription factor 1 (DMRT1) gene has long been linked to sex-determining pathways across vertebrates and is known to play an essential role in gonadal development and maintenance of spermatogenesis in mice. In humans, the genomic region harboring the DMRT gene cluster has been impli...

journal_title：Andrology

authors： Lima AC,Carvalho F,Gonçalves J,Fernandes S,Marques PI,Sousa M,Barros A,Seixas S,Amorim A,Conrad DF,Lopes AM

更新日期：2015-09-01 00:00:00

abstract：:Humanin (HN) has cytoprotective action on male germ cells after testicular stress induced by heat and hormonal deprivation. To examine whether HN has protective effects on chemotherapy-induced male germ cell apoptosis, we treated four groups of adult rats with (i) vehicle (control), (ii) HN, (iii) cyclophosphamide (CP...

journal_title：Andrology

authors： Surampudi P,Chang I,Lue Y,Doumit T,Jia Y,Atienza V,Liu PY,Swerdloff RS,Wang C

更新日期：2015-05-01 00:00:00

abstract：:Defects in bone regulatory pathways have been linked to chronic diseases including cardiovascular disease and cancer. In men, a link between bone metabolism and gonadal hormones has been suggested. However, to date, there is lack of evidence on the association between serum inorganic phosphate (Pi) and sex steroid hor...

journal_title：Andrology

authors： Wulaningsih W,Van Hemelrijck M,Michaelsson K,Kanarek N,Nelson WG,Ix JH,Platz EA,Rohrmann S

更新日期：2014-11-01 00:00:00

abstract：:The second messenger cyclic adenosine monophosphate (cAMP) has a central role in sperm physiology. Extracellular cAMP can be sequentially degraded into 5'AMP and adenosine by ecto-phosphodiesterases (ecto-PDE) and ecto-nucleotidases, a phenomenon called extracellular cAMP-adenosine pathway. As cAMP-adenosine pathway i...

journal_title：Andrology

authors： Bergeron A,Aragon JP,Guillemette C,Hébert A,Sullivan R,Blondin P,Richard FJ

更新日期：2016-11-01 00:00:00

abstract：:Erectile dysfunction (ED) is increasingly recognized as a public health problem. Several studies have reported the influence of the insertion/deletion (I/D) polymorphism in the Angiotensin-converting enzyme (ACE) gene on ED susceptibility, but the results remain controversial. To derive a more precise estimation of th...

journal_title：Andrology

authors： Zhang T,Li WL,He XF,Wu ZY,Liu LH,He SH,Wei AY

更新日期：2013-03-01 00:00:00

abstract：:In recent reports, an association between altered TRPC channel function and the development of various diabetic complications has drawn the attention of many investigators. The aim of this study was to investigate the expression of TRPC4 channels of corpus smooth muscle (CSM) cells in diabetes, and to evaluate the ass...

journal_title：Andrology

authors： Sung HH,Choo SH,Ko M,Kang SJ,Chae MR,Kam SC,Han DH,So I,Lee SW

更新日期：2014-07-01 00:00:00

abstract：:The main aim of this work was to evaluate how supplementing freezing media with reduced glutathione (GSH) affected the 'in vivo' fertilizing ability of boar semen subjected to cryopreservation procedures. With this purpose, 12 ejaculates coming from 12 boars were cryopreserved in the presence or absence of 2 mm GSH, w...

journal_title：Andrology

authors： Estrada E,Rodríguez-Gil JE,Rocha LG,Balasch S,Bonet S,Yeste M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The transcription factor DMRTB1 plays a pivotal role in coordinating the transition between mitosis and meiosis in murine germ cells. No reliable data are available for human testis. OBJECTIVES:The present study aims to examine the testicular expression pattern of DMRTB1 in men showing normal and impaired s...

journal_title：Andrology

authors： Hilbold E,Bergmann M,Fietz D,Kliesch S,Weidner W,Langeheine M,Rode K,Brehm R

更新日期：2019-07-01 00:00:00

abstract：:Growth hormone (GH) and insulin-like growth factor I (IGF-I) receptors are present on pituitary gonadotrophs and on testicular Leydig and Sertoli cells. Thus, the GH/IGF-I system may modulate the pituitary-gonadal axis in males. This is a randomized cross-over study. Eight healthy male volunteers (mean age 35, range 2...

journal_title：Andrology

authors： Andreassen M,Frystyk J,Faber J,Kristensen LØ,Juul A

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The presence of miRNAs in human reproductive tissue is intriguing and suggests the possibility that these important regulatory molecules play a role in reproductive function. However, the regulatory role of miRNAs in reproductive tissue remains poorly understood with a significant amount of controversial and...

journal_title：Andrology

authors： Salas-Huetos A,James ER,Aston KI,Carrell DT,Jenkins TG,Yeste M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Resistin is known as a potential mediator of obesity-associated insulin resistance. The high resistin level disrupts nitric oxide (NO)-mediated relaxation which is also important in erectile function. An antioxidant alkaloid, Boldine, is known as anti-diabetic and protects endothelial functions. OBJECTIVES:...

journal_title：Andrology

authors： Kara E,Kahraman E,Dayar E,Yetik Anacak G,Demir O,Gidener S,Atabey N,Durmus N

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Previous studies suggested that sperm head shape may serve as an effective indicator of semen quality. However, there lacks research with large sample and quantitative measurement. OBJECTIVES:The objective of this retrospective study was to explore the association between sperm head elongation (Width/Length...

journal_title：Andrology

authors： Chen F,Gao L,Zhou H,Guo L,Chen Q,Gan Y,Sun X,Li Q,Wang K

更新日期：2019-11-01 00:00:00

abstract：:Approximately 40% of middle-aged men exhibit symptoms of late-onset hypogonadism (LOH). However, the mechanism of androgen deficiency is still currently unclear. As shown in our previous studies, the SET protein is expressed in testicular Leydig cells and ovarian granule cells. This study was designed to investigate t...

journal_title：Andrology

authors： Zhang B,Ma W,Zhu Q,Xu W,Gao L,Xu B,Xu S,Gao C,Gao L,Liu J,Cui Y

更新日期：2018-05-01 00:00:00

abstract：:Tributyltin (TBT), a pesticide used in antifouling paints, is toxic for aquatic invertebrates. In vertebrates, TBT may act in obesogen- inducing adipogenetic gene transcription for adipocyte differentiation. In a previous study, we demonstrated that acute administration of TBT induces c-fos expression in the arcuate n...

journal_title：Andrology

authors： Bo E,Farinetti A,Marraudino M,Sterchele D,Eva C,Gotti S,Panzica G

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Germ cells have a unique and critical role as the conduit for hereditary information and therefore employ multiple strategies to protect genomic integrity and avoid mutations. Unlike somatic cells, which often respond to DNA damage by arresting the cell cycle and conducting DNA repair, germ cells as well as ...

journal_title：Andrology

authors： Bloom JC,Loehr AR,Schimenti JC,Weiss RS

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To investigate the possible role of serum norepinephrine (NE), leptin, and 5-hydroxytryptamine (5-HT) and their correlations with sympathetic skin response located in the penis (PSSR) in primary premature ejaculation (PPE). METHODS:We compared the serum level of NE, leptin, and 5-HT, intravaginal ejaculatory...

journal_title：Andrology

authors： Xia J,Zhang Q,Wang Y,Luan J,Yang J,Cong R,Wang Z,Song N

更新日期：2020-09-01 00:00:00

abstract：:Deletions on the long arm of the Y chromosome are a well-known cause of male infertility and it is generally accepted that deletions involving the AZFb region are not compatible with sperm production. Here, we report on two patients for whom basic diagnostic tests showed a deletion of the AZFb region. Unexpectedly, bo...

journal_title：Andrology

authors： Stouffs K,Vloeberghs V,Gheldof A,Tournaye H,Seneca S

更新日期：2017-07-01 00:00:00