Decreased activity of superoxide dismutase in the seminal plasma of infertile men correlates with increased sperm deoxyribonucleic acid fragmentation during the first hours after sperm donation.

abstract：:Growth hormone (GH) and insulin-like growth factor I (IGF-I) receptors are present on pituitary gonadotrophs and on testicular Leydig and Sertoli cells. Thus, the GH/IGF-I system may modulate the pituitary-gonadal axis in males. This is a randomized cross-over study. Eight healthy male volunteers (mean age 35, range 2...

journal_title：Andrology

authors： Andreassen M,Frystyk J,Faber J,Kristensen LØ,Juul A

更新日期：2013-07-01 00:00:00

abstract：:Highly active antiretroviral therapy has evolved over the years, leading to a boost in the quality of life in people living with HIV and AIDS. However, growing evidence has shown that highly active antiretroviral therapy has deleterious effects on the testes and the overall reproductive capacity. Therefore, this study...

journal_title：Andrology

authors： Adana MY,Akang EN,Peter AI,Jegede AI,Naidu ECS,Tiloke C,Chuturgoon AA,Azu OO

更新日期：2018-01-01 00:00:00

abstract：:The effects of equilibration times (E1, 2 h; E2, 4 h; E3, 6 h), freezing rates (FR1, manual, 5 cm above liquid nitrogen (LN2 ) for 10 min, plunging in LN2 ; FR2, programmable ultra-fast, holding at +4 °C for 2 min, from 4 to -10 °C at -10 °C/min, from -10 to -20 °C at -15 °C/min, from -20 to -120 °C at -60 °C/min, hol...

journal_title：Andrology

authors： Shah SA,Andrabi SM,Qureshi IZ

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is one of the risk factors for male subfertility/infertility. Malaysian propolis is reported to decrease hyperglycaemia in diabetic state. OBJECTIVES:The present study investigated the protective effect of Malaysian propolis on diabetes-induced subfertility/infertility. Additionally, its c...

journal_title：Andrology

authors： Nna VU,Bakar ABA,Ahmad A,Umar UZ,Suleiman JB,Zakaria Z,Othman ZA,Mohamed M

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Germ cell tumours are uniquely associated with the gametogenic tissues of males and females. A feature of these cancers is that they can express genes that are normally tightly restricted to meiotic cells. This aberrant gene expression has been used as an indicator that these cancer cells are attempting a pr...

journal_title：Andrology

authors： Feichtinger J,McFarlane RJ

更新日期：2019-07-01 00:00:00

abstract：:The medical treatment is indicated in the development stage of Peyronie's disease (PD) for at least 1 year after diagnosis and whenever in case of penile pain. This research was conducted to demonstrate the possible effectiveness of vitamin E in PD treatment, whereas in the scientific literature this topic is much dis...

journal_title：Andrology

authors： Paulis G,Brancato T,D'Ascenzo R,De Giorgio G,Nupieri P,Orsolini G,Alvaro R

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The existing classifications of varicocoeles have poor predictive value regarding the effects of surgery on sperm count. OBJECTIVE:To develop a new grading system for varicocoeles, useful as an indication for surgery. MATERIALS AND METHODS:This is a three-center prospective study which examined 173 men hav...

journal_title：Andrology

authors： Cavallini G,Scroppo FI,Colpi GM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Maximum urinary flow rate (Qmax) is usually increased after holmium laser enucleation of the prostate (HoLEP). However, improvements vary between patients and results regarding potential predictors of Qmax after HoLEP are inconsistent. Thus, we investigated pre-operative variables including second to fourth ...

journal_title：Andrology

authors： Park IN,Kim TB

更新日期：2019-03-01 00:00:00

abstract：:Low testosterone levels in aging men are associated with insulin resistance. Mitochondrial dysfunction, changes in glycogen metabolism, and lipid accumulation are linked to insulin resistance in skeletal muscle. In this randomized, double-blinded, placebo-controlled study, we investigated the effects of six-month test...

journal_title：Andrology

authors： Jensen RC,Christensen LL,Nielsen J,Schrøder HD,Kvorning T,Gejl K,Højlund K,Glintborg D,Andersen M

更新日期：2018-07-01 00:00:00

abstract：:Increasing evidence disclosed the existence of a novel multi-organ endocrine pathway, involving bone, pancreas and testis, of high penetrance in energy metabolism and male fertility. The main mediator of this axis is undercarboxylated osteocalcin (ucOC), a bone-derived protein-exerting systemic effects on tissues expr...

journal_title：Andrology

authors： De Toni L,Di Nisio A,Rocca MS,De Rocco Ponce M,Ferlin A,Foresta C

更新日期：2017-07-01 00:00:00

abstract：:In recent reports, an association between altered TRPC channel function and the development of various diabetic complications has drawn the attention of many investigators. The aim of this study was to investigate the expression of TRPC4 channels of corpus smooth muscle (CSM) cells in diabetes, and to evaluate the ass...

journal_title：Andrology

authors： Sung HH,Choo SH,Ko M,Kang SJ,Chae MR,Kam SC,Han DH,So I,Lee SW

更新日期：2014-07-01 00:00:00

abstract：:Fibroblast growth factors (FGFs) and their receptors (FGFRs) regulate several functions of somatic cells. In a previous work, we reported FGFR expression in human spermatozoa and their involvement in motility. This study aimed to evaluate the presence and localization of fibroblast growth factor 2 (FGF2) in human sper...

journal_title：Andrology

authors： Garbarino Azúa DJ,Saucedo L,Giordana S,Magri ML,Buffone MG,Neuspiller F,Vazquez-Levin MH,Marín-Briggiler CI

更新日期：2017-09-01 00:00:00

abstract：:Erectile dysfunction (ED) is increasingly recognized as a public health problem. Several studies have reported the influence of the insertion/deletion (I/D) polymorphism in the Angiotensin-converting enzyme (ACE) gene on ED susceptibility, but the results remain controversial. To derive a more precise estimation of th...

journal_title：Andrology

authors： Zhang T,Li WL,He XF,Wu ZY,Liu LH,He SH,Wei AY

更新日期：2013-03-01 00:00:00

abstract：:Peyronie's disease (PD) is an under-diagnosed condition with prevalence in the male population as high as 9%. It is a localized connective tissue disorder of the penis characterized by scarring of the tunica albuginea. Its pathophysiology, however, remains incompletely elucidated. For the management of the acute phase...

journal_title：Andrology

authors： Yafi FA,Pinsky MR,Sangkum P,Hellstrom WJ

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Regulatory bodies recommend inconsistent ejaculatory abstinence lengths before semen analysis. The literature exploring the effect of ejaculatory abstinence length on the outcomes of intracytoplasmic sperm injection is scarce. OBJECTIVE:To study the influence of ejaculatory abstinence length on semen qualit...

journal_title：Andrology

authors： Borges E Jr,Braga DPAF,Zanetti BF,Iaconelli A Jr,Setti AS

更新日期：2019-03-01 00:00:00

abstract：:Pubertal gynecomastia is a common condition observed in up to 65% of adolescent males. It is usually idiopathic and tends to regress within 1-2 years. In this descriptive cross-sectional study, we investigated 25 adolescent males with prominent (>B3) and/or persistent (>2 years) pubertal gynecomastia (P/PPG) to determ...

journal_title：Andrology

authors： Paris F,Gaspari L,Mbou F,Philibert P,Audran F,Morel Y,Biason-Lauber A,Sultan C

更新日期：2016-03-01 00:00:00

abstract：:Deletions on the long arm of the Y chromosome are a well-known cause of male infertility and it is generally accepted that deletions involving the AZFb region are not compatible with sperm production. Here, we report on two patients for whom basic diagnostic tests showed a deletion of the AZFb region. Unexpectedly, bo...

journal_title：Andrology

authors： Stouffs K,Vloeberghs V,Gheldof A,Tournaye H,Seneca S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Previous studies suggested that sperm head shape may serve as an effective indicator of semen quality. However, there lacks research with large sample and quantitative measurement. OBJECTIVES:The objective of this retrospective study was to explore the association between sperm head elongation (Width/Length...

journal_title：Andrology

authors： Chen F,Gao L,Zhou H,Guo L,Chen Q,Gan Y,Sun X,Li Q,Wang K

更新日期：2019-11-01 00:00:00

abstract：:Exosomes are membranous nanovesicles of endocytic origin that carry and transfer regulatory bioactive molecules and mediate intercellular communication between cells and tissues. Although seminal exosomes have been identified in human seminal plasma, their exact composition and possible physiologic function remain unk...

journal_title：Andrology

authors： Yang C,Guo WB,Zhang WS,Bian J,Yang JK,Zhou QZ,Chen MK,Peng W,Qi T,Wang CY,Liu CD

更新日期：2017-09-01 00:00:00

abstract：:Semen analysis is commonly used as a tool to assess the fertility potential of a male, despite its relatively low predictive power. In this study, we have assessed associations between semen analysis findings (low count, low motility, low viability, poor sperm penetration assay results, poor morphology, and increased ...

journal_title：Andrology

authors： Jenkins TG,Aston KI,Hotaling JM,Shamsi MB,Simon L,Carrell DT

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Resistin is known as a potential mediator of obesity-associated insulin resistance. The high resistin level disrupts nitric oxide (NO)-mediated relaxation which is also important in erectile function. An antioxidant alkaloid, Boldine, is known as anti-diabetic and protects endothelial functions. OBJECTIVES:...

journal_title：Andrology

authors： Kara E,Kahraman E,Dayar E,Yetik Anacak G,Demir O,Gidener S,Atabey N,Durmus N

更新日期：2020-11-01 00:00:00

abstract：:Testosterone (T) deficiency, sexual dysfunction, obesity and obstructive sleep apnea (OSA) are common and often coexist. T prescriptions have increased worldwide during the last decade, including to those with undiagnosed or untreated OSA. The effect of T administration on sexual function, neurocognitive performance a...

journal_title：Andrology

authors： Melehan KL,Hoyos CM,Yee BJ,Wong KK,Buchanan PR,Grunstein RR,Liu PY

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:We previously demonstrated how mouse spermatozoa can be efficiently stored for two years in a -80°C freezer, maintaining their ability to fertilize mouse eggs. OBJECTIVES:The main objective here was to evaluate the effects of five years at -80°C compared to liquid nitrogen storage (LN2 , control condition) ...

journal_title：Andrology

authors： Raspa M,Putti S,Paoletti R,Barboni B,Ramal-Sanchez M,Lanuti P,Marchisio M,D'Atri M,Ortolani C,Papa S,Valbonetti L,Bernabo N,Scavizzi F

更新日期：2021-01-11 00:00:00

abstract：:A recent study has demonstrated that porcine spermatozoa recognize with high affinity carbohydrate structures containing Lewis X motifs. Sperm adhesion to Lewis X is proposed to mediate sperm binding to the oviduct epithelium to form a reservoir. The objective of this study was to identify Lewis X-binding proteins fro...

journal_title：Andrology

authors： Silva E,Frost D,Li L,Bovin N,Miller DJ

更新日期：2017-05-01 00:00:00

abstract：:Erectile Dysfunction is considered a multifactorial disease, where organic and psychological aspects are often interconnected. In a randomized controlled pilot study, we compared the efficacy of combined vardenafil orodispersible tablet (VARD) and cognitive-behavioral sex therapy (CBST) vs. VARD alone in improving sex...

journal_title：Andrology

authors： Boddi V,Castellini G,Casale H,Rastrelli G,Boni L,Corona G,Maggi M

更新日期：2015-09-01 00:00:00

abstract：:Presence of vacuoles and degree of sperm DNA damage are considered to be the basic factors used for the assessment of sperm fertilization capacity. We aimed to investigate the link between these two parameters. According to our knowledge, this is the first study where the Comet assay was used to assess the degree of D...

journal_title：Andrology

authors： Pastuszek E,Kiewisz J,Skowronska P,Liss J,Lukaszuk M,Bruszczynska A,Jakiel G,Lukaszuk K

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Concerns exist about the effect of delaying treatment for prostate cancer (PCa) regarding both oncological and functional outcomes after radical prostatectomy (RP). OBJECTIVE:To assess the impact of time from diagnosis to RP on post-operative erectile function (EF) outcomes. MATERIALS AND METHODS:We analyz...

journal_title：Andrology

authors： Schifano N,Capogrosso P,Pozzi E,Ventimiglia E,Cazzaniga W,Matloob R,Gandaglia G,Dehò F,Briganti A,Montorsi F,Salonia A

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Oocyte activation is driven by intracellular calcium (Ca2+ ) oscillations induced by sperm-specific PLCζ, abrogation of which causes oocyte activation deficiency in humans. Clinical PLCζ investigations have been limited to severe male infertility conditions, while PLCζ levels and localisation patterns have y...

journal_title：Andrology

authors： Kashir J,Mistry BV,BuSaleh L,Abu-Dawas R,Nomikos M,Ajlan A,Abu-Dawud R,AlYacoub N,AlHassan S,Lai FA,Assiri AM,Coskun S

更新日期：2020-09-01 00:00:00

abstract：:Estrogens are involved in growth, differentiation and pathogenesis of human prostate through the mediation of the classical estrogen receptors ERα and ERβ. The G protein-coupled estrogen receptor (GPER) is a 'novel' mediator of estrogen signaling which has been recently recognized in some human reproductive tissues, b...

journal_title：Andrology

authors： Rago V,Romeo F,Giordano F,Ferraro A,Carpino A

更新日期：2016-01-01 00:00:00

abstract：:The discontinuation rate with phosphodiesterase type 5 inhibitors (PDE5i) remains very high. The aim of this study was to review and meta-analyze currently available data regarding dropout of the first-generation of PDE5i including sildenafil, vardenafil, and tadalafil. An extensive Medline Embase and Cochrane search ...

journal_title：Andrology

authors： Corona G,Rastrelli G,Burri A,Serra E,Gianfrilli D,Mannucci E,Jannini EA,Maggi M

更新日期：2016-11-01 00:00:00