Adult exposure to tributyltin affects hypothalamic neuropeptide Y, Y1 receptor distribution, and circulating leptin in mice.

abstract：:Erectile Dysfunction is considered a multifactorial disease, where organic and psychological aspects are often interconnected. In a randomized controlled pilot study, we compared the efficacy of combined vardenafil orodispersible tablet (VARD) and cognitive-behavioral sex therapy (CBST) vs. VARD alone in improving sex...

journal_title：Andrology

authors： Boddi V,Castellini G,Casale H,Rastrelli G,Boni L,Corona G,Maggi M

更新日期：2015-09-01 00:00:00

abstract：:Spermiogenesis is the final phase of spermatogenesis. During this process, haploid round spermatids differentiate into spermatozoa, with dramatic morphological changes, including elongation and condensation of the nuclei, and formation of the flagella. Meig1 is one of many genes involved in the regulation of this proc...

journal_title：Andrology

authors： Shi Y,Zhang L,Song S,Teves ME,Li H,Wang Z,Hess RA,Jiang G,Zhang Z

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The presence of miRNAs in human reproductive tissue is intriguing and suggests the possibility that these important regulatory molecules play a role in reproductive function. However, the regulatory role of miRNAs in reproductive tissue remains poorly understood with a significant amount of controversial and...

journal_title：Andrology

authors： Salas-Huetos A,James ER,Aston KI,Carrell DT,Jenkins TG,Yeste M

更新日期：2020-01-01 00:00:00

abstract：:Escherichia coli (E. coli) is a common pathogen in epididymitis, which represents a prevalent entity in male reproductive tract infections (RTI). Although current treatment regimens using antibiotics are satisfactory, development of antimicrobial resistance by the pathogen represents a challenge in the management of R...

journal_title：Andrology

authors： Biswas B,Bhushan S,Rajesh A,Suraj SK,Lu Y,Meinhardt A,Yenugu S

更新日期：2015-03-01 00:00:00

abstract：:Erectile dysfunction (ED) is very prevalent in the older population, although the ageing-related mechanisms involved in the development of ED are poorly understood. We propose that age-induced differences in nerve- and endothelium-mediated smooth muscle contractility in the corpus cavernosum (CC) could be found betwee...

journal_title：Andrology

authors： Lafuente-Sanchis A,Triguero D,Garcia-Pascual A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The association between alcohol intake and male reproductive function is still controversial. In the frame of a prospective cohort study, designed to investigate the relation between life style and fertility, we performed a cross-sectional analysis of semen quality. METHODS:Men of subfertile couples, referr...

journal_title：Andrology

authors： Ricci E,Noli S,Ferrari S,La Vecchia I,Cipriani S,De Cosmi V,Somigliana E,Parazzini F

更新日期：2018-09-01 00:00:00

abstract：:Testicular germ cell tumours (TGCT) typically contain high numbers of infiltrating immune cells, yet the functional nature and consequences of interactions between GCNIS (germ cell neoplasia in situ) or seminoma cells and immune cells remain unknown. A co-culture model using the seminoma-derived TCam-2 cell line and p...

journal_title：Andrology

authors： Klein B,Schuppe HC,Bergmann M,Hedger MP,Loveland BE,Loveland KL

更新日期：2017-07-01 00:00:00

abstract：:In recent reports, an association between altered TRPC channel function and the development of various diabetic complications has drawn the attention of many investigators. The aim of this study was to investigate the expression of TRPC4 channels of corpus smooth muscle (CSM) cells in diabetes, and to evaluate the ass...

journal_title：Andrology

authors： Sung HH,Choo SH,Ko M,Kang SJ,Chae MR,Kam SC,Han DH,So I,Lee SW

更新日期：2014-07-01 00:00:00

abstract：STUDY QUESTION:Are de novo mutations in the human genome associated with male infertility? SUMMARY ANSWER:We identified de novo mutations in five candidate genes: SEMA5A, NEURL4, BRD2, CD1D, and CD63. WHAT IS KNOWN ALREADY:Epidemiological and genetic studies have consistently indicated contribution of genetic factors...

journal_title：Andrology

authors： Hodžić A,Maver A,Plaseska-Karanfilska D,Ristanović M,Noveski P,Zorn B,Terzic M,Kunej T,Peterlin B

更新日期：2021-01-01 00:00:00

abstract：:Genomic and protein-coding transcriptomic data have suggested that germ cell tumours (GCTs) of childhood are biologically distinct from those of adulthood. Global messenger RNA profiles segregate malignant GCTs primarily by histology, but then also by age, with numerous transcripts showing age-related differential exp...

journal_title：Andrology

authors： Murray MJ,Nicholson JC,Coleman N

更新日期：2015-01-01 00:00:00

abstract：:Semen quality is suggested to be a universal biomarker for future health. Previous studies have mostly been registry based excluding the possibility to address the importance of lifestyle, fertility status, health and socio-economic status. We aimed to investigate whether the association between semen quality and subs...

journal_title：Andrology

authors： Latif T,Lindahl-Jacobsen R,Mehlsen J,Eisenberg ML,Holmboe SA,Pors K,Brinth L,Skouby SO,Jørgensen N,Jensen TK

更新日期：2018-05-01 00:00:00

abstract：:The main aim of this work was to evaluate how supplementing freezing media with reduced glutathione (GSH) affected the 'in vivo' fertilizing ability of boar semen subjected to cryopreservation procedures. With this purpose, 12 ejaculates coming from 12 boars were cryopreserved in the presence or absence of 2 mm GSH, w...

journal_title：Andrology

authors： Estrada E,Rodríguez-Gil JE,Rocha LG,Balasch S,Bonet S,Yeste M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Penile cancer represents a rare pathology whose natural history of treatment is poorly understood. OBJECTIVE:To illustrate the dynamic survival profiles in surgically treated patients with squamous cell carcinoma of the penis (SCCP) using the conditional survival (CS) estimates. MATERIALS AND METHODS:Patie...

journal_title：Andrology

authors： Liu W,Luo Y,Wang G,Li N,Wang Z,Lei J,Wang X

更新日期：2020-11-01 00:00:00

abstract：:Approximately 40% of middle-aged men exhibit symptoms of late-onset hypogonadism (LOH). However, the mechanism of androgen deficiency is still currently unclear. As shown in our previous studies, the SET protein is expressed in testicular Leydig cells and ovarian granule cells. This study was designed to investigate t...

journal_title：Andrology

authors： Zhang B,Ma W,Zhu Q,Xu W,Gao L,Xu B,Xu S,Gao C,Gao L,Liu J,Cui Y

更新日期：2018-05-01 00:00:00

abstract：:Low testosterone levels in aging men are associated with insulin resistance. Mitochondrial dysfunction, changes in glycogen metabolism, and lipid accumulation are linked to insulin resistance in skeletal muscle. In this randomized, double-blinded, placebo-controlled study, we investigated the effects of six-month test...

journal_title：Andrology

authors： Jensen RC,Christensen LL,Nielsen J,Schrøder HD,Kvorning T,Gejl K,Højlund K,Glintborg D,Andersen M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is one of the risk factors for male subfertility/infertility. Malaysian propolis is reported to decrease hyperglycaemia in diabetic state. OBJECTIVES:The present study investigated the protective effect of Malaysian propolis on diabetes-induced subfertility/infertility. Additionally, its c...

journal_title：Andrology

authors： Nna VU,Bakar ABA,Ahmad A,Umar UZ,Suleiman JB,Zakaria Z,Othman ZA,Mohamed M

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The current results of in vitro reproduction techniques in pigs, such as in vitro fertilization (IVF) and embryo development, show high performance with both epididymal and ejaculated spermatozoa. However, the results using ejaculated spermatozoa are even better. Ejaculated spermatozoa are exposed to the sec...

journal_title：Andrology

authors： Soriano-Úbeda C,Avilés-López K,García-Vázquez FA,Romero-Aguirregomezcorta J,Matás C

更新日期：2021-01-01 00:00:00

abstract：:Maternal overweight and obesity in pregnancy has been associated with earlier age of menarche in daughters as well as reduced semen quality in sons. We aimed at investigating pubertal development in sons born by mothers with a high body mass index (BMI). The study included 2522 sons of mothers that during pregnancy in...

journal_title：Andrology

authors： Hounsgaard ML,Håkonsen LB,Vested A,Thulstrup AM,Olsen J,Bonde JP,Nohr EA,Ramlau-Hansen CH

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Regulatory bodies recommend inconsistent ejaculatory abstinence lengths before semen analysis. The literature exploring the effect of ejaculatory abstinence length on the outcomes of intracytoplasmic sperm injection is scarce. OBJECTIVE:To study the influence of ejaculatory abstinence length on semen qualit...

journal_title：Andrology

authors： Borges E Jr,Braga DPAF,Zanetti BF,Iaconelli A Jr,Setti AS

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The transcription factor DMRTB1 plays a pivotal role in coordinating the transition between mitosis and meiosis in murine germ cells. No reliable data are available for human testis. OBJECTIVES:The present study aims to examine the testicular expression pattern of DMRTB1 in men showing normal and impaired s...

journal_title：Andrology

authors： Hilbold E,Bergmann M,Fietz D,Kliesch S,Weidner W,Langeheine M,Rode K,Brehm R

更新日期：2019-07-01 00:00:00

abstract：:Exosomes are membranous nanovesicles of endocytic origin that carry and transfer regulatory bioactive molecules and mediate intercellular communication between cells and tissues. Although seminal exosomes have been identified in human seminal plasma, their exact composition and possible physiologic function remain unk...

journal_title：Andrology

authors： Yang C,Guo WB,Zhang WS,Bian J,Yang JK,Zhou QZ,Chen MK,Peng W,Qi T,Wang CY,Liu CD

更新日期：2017-09-01 00:00:00

abstract：:Tamoxifen is an off-label option to treat men for breast cancer, infertility, and idiopathic gynecomastia. Lately, tamoxifen has been proposed as a treatment to prevent gynecomastia in prostate cancer patients receiving antiandrogen therapy. We reviewed the adverse events (AEs) reported in studies of men prescribed ta...

journal_title：Andrology

authors： Wibowo E,Pollock PA,Hollis N,Wassersug RJ

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:At the beginning of the 20th century, the Viennese physiologist Eugen Steinach proposed to treat the effects of physiological ageing by vasectomy. After experimenting his theory with animal, he published his results, and convinced scientists to apply this method to humans (ie men). The scientific community h...

journal_title：Andrology

authors： Benmoussa N,Charlier P,Rebibo JD

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:Testicular germ cell tumour (TGCT) is a malignancy with a high heritable component. The inherited risk is polygenic, and around 50 susceptibility genes are identified. The functional role of the gene products for TGCT development is not well understood. The focus of this review is functional studies of geneti...

journal_title：Andrology

authors： Das MK,Kleppa L,Haugen TB

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Men with congenital unilateral absence of vas deferens were reported to be mainly azoospermic, with both unilateral renal absence and mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) but some have neither. OBJECTIVES:To assess whether in infertile couples the male partners with co...

journal_title：Andrology

authors： Mieusset R,Bieth E,Daudin M,Isus F,Delaunay B,Bujan L,Monteil L,Fauquet I,Huyghe E,Hamdi SM

更新日期：2020-05-01 00:00:00

abstract：:Most of the non-obstructive azoospermia (NOA)-patients have only focal spermatogenesis which results in insufficient numbers of spermatozoa to reach the ejaculate. In ≈50% of these NOA-patients testicular sperm extraction (TESE) is successful and intracytoplasmic sperm injection (ICSI) is pursued. We studied whether (...

journal_title：Andrology

authors： Hessel M,de Vries M,D'Hauwers KW,Fleischer K,Hulsbergen-van de Kaa CA,Braat DD,Ramos L

更新日期：2015-05-01 00:00:00

abstract：:Prevalence and risk factors of concomitant primary low sexual desire/interest (LSD/I) and subsequent new-onset erectile dysfunction (ED) in men have been only partially investigated. We looked at the sociodemographic and clinical predictors of the concomitant condition of primary LSD/I - defined as the reduction in th...

journal_title：Andrology

authors： Salonia A,Clementi MC,Ventimiglia E,Colicchia M,Capogrosso P,Castiglione F,Castagna G,Boeri L,Suardi N,Cantiello F,Damiano R,Montorsi F

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Bulls are of great importance in the productive chain and for this reason they should have a good semen quality. There is no doubt that sperm morphology is very important to bull fertility, although little is known about how exactly the abnormal morphologies may affect sperm functions. OBJECTIVES:To detail ...

journal_title：Andrology

authors： Díaz-Miranda EA,Maitan PP,Machado TP,Camilo BS,Lima DA,Okano DS,Penitente-Filho JM,Machado-Neves M,de Oliveira LL,Guimarães SEF,da Costa EP,Guimarães JD

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Previous studies suggested that sperm head shape may serve as an effective indicator of semen quality. However, there lacks research with large sample and quantitative measurement. OBJECTIVES:The objective of this retrospective study was to explore the association between sperm head elongation (Width/Length...

journal_title：Andrology

authors： Chen F,Gao L,Zhou H,Guo L,Chen Q,Gan Y,Sun X,Li Q,Wang K

更新日期：2019-11-01 00:00:00

abstract：:The molecular basis of spermatogenic failure (SpF) is still largely unknown. Accumulating evidence suggests that a series of specific events such as meiosis, are determined at the early stage of spermatogenesis. This study aims to assess the expression profile of pre-meiotic genes of infertile testicular biopsies that...

journal_title：Andrology

authors： Bonache S,Algaba F,Franco E,Bassas L,Larriba S

更新日期：2014-07-01 00:00:00