Maintaining physical activity during refeeding improves body composition, intestinal hyperpermeability and behavior in anorectic mice.

abstract：:Alzheimer's disease (AD) is mainly characterized by the deposition of extracellular amyloid plaques and intracellular accumulation of neurofibrillary tangles (NFTs). While the recent 5xFAD AD mouse model exhibits many AD-related phenotypes and a relatively early and aggressive amyloid β production, it does not show NF...

journal_title：Scientific reports

authors： Kang S,Kim J,Chang KA

更新日期：2021-01-14 00:00:00

abstract：:Genetically encoded calcium indicators and optogenetic actuators can report and manipulate the activity of specific neuronal populations. However, applying imaging and optogenetics simultaneously has been difficult to establish in the mammalian brain, even though combining the techniques would provide a powerful appro...

journal_title：Scientific reports

authors： Bovetti S,Moretti C,Zucca S,Dal Maschio M,Bonifazi P,Fellin T

更新日期：2017-01-05 00:00:00

abstract：:The continuous search for natural products that attenuate age-related losses has increasingly gained notice; among them, those applicable for skin care have drawn significant attention. The bioester generated from the Chenopodium quinoa's oil is a natural-origin ingredient described to produce replenishing skin effect...

journal_title：Scientific reports

authors： Camillo-Andrade AC,Santos MDM,Fischer JSG,Swinka BB,Bosquetti B,Schuck DC,Pincerati MR,Lorencini M,Carvalho PC

更新日期：2020-11-10 00:00:00

abstract：:Understanding ethanol-induced stresses and responses in biofuel-producing bacteria at systems level has significant implications in engineering more efficient biofuel producers. We present a computational study of transcriptomic and genomic data of both ethanol-stressed and ethanol-adapted E. coli cells with computati...

journal_title：Scientific reports

authors： Cao H,Wei D,Yang Y,Shang Y,Li G,Zhou Y,Ma Q,Xu Y

更新日期：2017-03-16 00:00:00

abstract：:Viral infection triggers a series of signaling cascades, which converge to activate the transcription factors nuclear factor-κB (NF-κB) and interferon regulatory factor 3 (IRF3), thereby inducing the transcription of type I interferons (IFNs). Although not fully characterized, these innate antiviral responses are fine...

journal_title：Scientific reports

authors： Zhang H,Wang D,Zhong H,Luo R,Shang M,Liu D,Chen H,Fang L,Xiao S

更新日期：2015-06-10 00:00:00

abstract：:Linearly polarized microwave radiation is shown to have its plane of polarization converted to the orthogonal state upon reflection from an ultrathin (λ/25) cavity array. The structure benefits from an uncomplicated design consisting of a metallic grating closely separated from a ground plane by a dielectric spacer. A...

journal_title：Scientific reports

authors： Tremain B,Rance HJ,Hibbins AP,Sambles JR

更新日期：2015-03-23 00:00:00

abstract：:Neuroinflammation is involved in the pathogenesis of Parkinson's disease (PD) and other neurodegenerative disorders. We show that lack of PINK1- a mitochondrial kinase linked to recessive familial PD - leads to glia type-specific abnormalities of innate immunity. PINK1 loss enhances LPS/IFN-γ stimulated pro-inflammato...

journal_title：Scientific reports

authors： Sun L,Shen R,Agnihotri SK,Chen Y,Huang Z,Büeler H

更新日期：2018-01-10 00:00:00

abstract：:Some ant species have multiple worker castes that differ in body size; workers in one caste remain in the colony and those in the other forage outside the colony (caste polyethism). In other species, all workers engage in both tasks, but the younger workers remain in the colony and the older workers forage (age polyet...

journal_title：Scientific reports

authors： Iwasa Y,Yamaguchi S

更新日期：2020-02-24 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Uranga RM,Millán C,Barahona MJ,Recabal A,Salgado M,Martinez F,Ordenes P,Elizondo-Vega R,Sepúlveda F,Uribe E,García-Robles MLÁ

更新日期：2019-08-28 00:00:00

abstract：:Studies on the evolution of parental care have focused primarily on the costs and benefits of parental care and the life-history attributes that favour it. However, once care evolves, offspring in some taxa appear to become increasingly dependent on their parents. Although offspring dependency is a central theme in fa...

journal_title：Scientific reports

authors： Capodeanu-Nägler A,Keppner EM,Vogel H,Ayasse M,Eggert AK,Sakaluk SK,Steiger S

更新日期：2016-07-05 00:00:00

abstract：:The ryanodine receptor 1 is a large calcium ion channel found in mammalian skeletal muscle. The ion channel gained a lot of attention recently, after multiple independent authors published near-atomic cryo electron microscopy data. Taking advantage of the unprecedented quality of structural data, we performed molecula...

journal_title：Scientific reports

authors： Heinz LP,Kopec W,de Groot BL,Fink RHA

更新日期：2018-05-02 00:00:00

abstract：:Empowering an indirect band-gap material like Si with optical functionalities, firstly light emission, represents a huge advancement constantly pursued in the realization of any integrated photonic device. We report the demonstration of giant photoluminescence (PL) emission by a newly synthesized material consisting o...

journal_title：Scientific reports

authors： Faraci G,Pennisi AR,Alberti A,Ruggeri R,Mannino G

更新日期：2013-01-01 00:00:00

abstract：:Persistent shortage and heterogeneous quality of liver grafts encourages the optimization of donor-recipient matching in liver transplantation (LT). We explored whether or not there was a survival benefit (SB) of LT according to the quality of grafts assessed by the Donor Quality Index (DQI) and recipients' disease se...

journal_title：Scientific reports

authors： Winter A,Féray C,Antoine C,Azoulay D,Daurès JP,Landais P

更新日期：2020-03-05 00:00:00

abstract：:Potassium depletion affects AQP2 expression and the cellular composition of the kidney collecting duct. This, in turn, contributes to the development of a secondary form of nephrogenic diabetes insipidus and hypokalemic nephropathy. Here we show that after 14 days of potassium depletion, the cellular fraction of A-typ...

journal_title：Scientific reports

authors： Iervolino A,Prosperi F,De La Motte LR,Petrillo F,Spagnuolo M,D'Acierno M,Siccardi S,Perna AF,Christensen BM,Frische S,Capasso G,Trepiccione F

更新日期：2020-03-31 00:00:00

abstract：:Cytochrome P450 monooxygenases (P450s) are heme-thiolate proteins whose role as drug targets against pathogens, as well as in valuable chemical production and bioremediation, has been explored. In this study we performed comprehensive comparative analysis of P450s in 13 newly explored oomycete pathogens. Three hundred...

journal_title：Scientific reports

authors： Sello MM,Jafta N,Nelson DR,Chen W,Yu JH,Parvez M,Kgosiemang IKR,Monyaki R,Raselemane SC,Qhanya LB,Mthakathi NT,Sitheni Mashele S,Syed K

更新日期：2015-07-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is characterized by failure of ovulation and is associated with obesity and chronic inflammation. Recent evidence suggests that anomalous activation of ovarian macrophages and numerical and functional deficits in the Th17 (CD4+IL17A+) and the CD4+CD25+CD127low Tregs plays crucial role ...

journal_title：Scientific reports

authors： Albaghdadi AJH,Feeley CA,Kan FWK

更新日期：2019-04-25 00:00:00

abstract：:NETs constitute a network of DNA and proteins released by neutrophils in response to infectious and immunologic triggers. NET proteins are recognized as autoantigens in ANCA vasculitis; limited knowledge is available in other autoimmune pathologies. The composition of NETs produced ex vivo by resting and Phorbol-myris...

journal_title：Scientific reports

authors： Bruschi M,Petretto A,Santucci L,Vaglio A,Pratesi F,Migliorini P,Bertelli R,Lavarello C,Bartolucci M,Candiano G,Prunotto M,Ghiggeri GM

更新日期：2019-05-28 00:00:00

abstract：:This work aimed to use artificial intelligence to predict subjective refraction from wavefront aberrometry data processed with a novel polynomial decomposition basis. Subjective refraction was converted to power vectors (M, J0, J45). Three gradient boosted trees (XGBoost) algorithms were trained to predict each power ...

journal_title：Scientific reports

authors： Rampat R,Debellemanière G,Malet J,Gatinel D

更新日期：2020-05-22 00:00:00

abstract：:Nanodiamond (ND) has emerged as a promising carbon nanomaterial for therapeutic applications. In previous studies, ND has been reported to have outstanding biocompatibility and high uptake rate in various cell types. ND containing nitrogen-vacancy centers exhibit fluorescence property is called fluorescent nanodiamond...

journal_title：Scientific reports

authors： Huang YA,Kao CW,Liu KK,Huang HS,Chiang MH,Soo CR,Chang HC,Chiu TW,Chao JI,Hwang E

更新日期：2014-11-05 00:00:00

abstract：:Microvascular endothelial cell heterogeneity and its relationship to hemodynamics remains poorly understood due to a lack of sufficient methods to examine these parameters in vivo at high resolution throughout an angiogenic network. The availability of surrogate markers for functional vascular proteins, such as green ...

journal_title：Scientific reports

authors： Kelly-Goss MR,Ning B,Bruce AC,Tavakol DN,Yi D,Hu S,Yates PA,Peirce SM

更新日期：2017-08-22 00:00:00

abstract：:This study aimed to determine the role of magnetic resonance imaging (MRI) in diagnosing and describing the characteristics of fistula-in-ano, and the agreement between MRI and operative findings. We conducted a retrospective study in 367 patients with fistula-in-ano who were diagnosed and had an operation at the Univ...

journal_title：Scientific reports

authors： Vo D,Phan C,Nguyen L,Le H,Nguyen T,Pham H

更新日期：2019-11-29 00:00:00

abstract：:Plutonium and radiocaesium are hazardous contaminants released by the Fukushima Daiichi nuclear power plant (FDNPP) disaster and their distribution in the environment requires careful characterisation using isotopic information. Comprehensive spatial survey of 134Cs and 137Cs has been conducted on a regular basis sinc...

journal_title：Scientific reports

authors： Dunne JA,Martin PG,Yamashiki Y,Ang IXY,Scott TB,Richards DA

更新日期：2018-11-14 00:00:00

abstract：:Surface plasmon resonators can drastically redistribute incident light over different output wave vectors and polarizations. This can lead for instance to sub-diffraction sized nanoapertures in metal films that beam and to nanoparticle antennas that enable efficient conversion of photons between spatial modes, or heli...

journal_title：Scientific reports

authors： Osorio CI,Mohtashami A,Koenderink AF

更新日期：2015-04-30 00:00:00

abstract：:The human brain has evolved specialised mechanisms to enable the rapid detection of threat cues, including emotional face expressions (e.g., fear and anger). However, contextual cues - such as gaze direction - influence the ability to recognise emotional expressions. For instance, anger paired with direct gaze, and fe...

journal_title：Scientific reports

authors： Caruana N,Inkley C,Zein ME,Seymour K

更新日期：2019-11-07 00:00:00

abstract：:The interlocking roles of lexical, syntactic and semantic processing in language comprehension has been the subject of longstanding debate. Recently, the cortical response to a frequency-tagged linguistic stimulus has been shown to track the rate of phrase and sentence, as well as syllable, presentation. This could be...

journal_title：Scientific reports

authors： Burroughs A,Kazanina N,Houghton C

更新日期：2021-01-28 00:00:00

abstract：:Carabids are considered beneficial arthropods in agroecosystems, where they prey on crop pests or consume weed seeds. Therefore, knowledge of the spatial distribution of carabids in agricultural landscapes is crucial to efficiently manage the ecosystem services that they provide. In the present study, we investigated ...

journal_title：Scientific reports

authors： Knapp M,Seidl M,Knappová J,Macek M,Saska P

更新日期：2019-06-20 00:00:00

abstract：:Ectoine synthase (EctC) is the signature enzyme for the production of ectoine, a compatible solute and chemical chaperone widely synthesized by bacteria as a cellular defense against the detrimental effects of osmotic stress. EctC catalyzes the last step in ectoine synthesis through cyclo-condensation of the EctA-form...

journal_title：Scientific reports

authors： Czech L,Höppner A,Kobus S,Seubert A,Riclea R,Dickschat JS,Heider J,Smits SHJ,Bremer E

更新日期：2019-01-23 00:00:00

abstract：:We have observed that one in three patients admitted to the Neurological Rehabilitation Ward for Children and Adolescents due to a syndrome or disease associated with neurodysfunction is short of stature for their age. In order to identify the relationship between growth defects (short stature) and syndromes or diseas...

journal_title：Scientific reports

authors： Perenc L,Guzik A,Podgórska-Bednarz J,Drużbicki M

更新日期：2019-11-11 00:00:00

abstract：:Papillary thyroid carcinoma (PTC) displays strong but so far largely uncharacterized heritability. Here we studied genetic predisposition in a family with six affected individuals. We genotyped all available family members and conducted whole exome sequencing of blood DNA from two affected individuals. Haplotype analy...

journal_title：Scientific reports

authors： Tomsic J,He H,Akagi K,Liyanarachchi S,Pan Q,Bertani B,Nagy R,Symer DE,Blencowe BJ,de la Chapelle A

更新日期：2015-07-02 00:00:00

abstract：:Open-ended evolution (OEE) is relevant to a variety of biological, artificial and technological systems, but has been challenging to reproduce in silico. Most theoretical efforts focus on key aspects of open-ended evolution as it appears in biology. We recast the problem as a more general one in dynamical systems theo...

journal_title：Scientific reports

authors： Adams A,Zenil H,Davies PCW,Walker SI

更新日期：2017-04-20 00:00:00