Diabetes Management and Cardiovascular Risk: Are SGLT-2 Inhibitors the Safest?

abstract：BACKGROUND:We compared the lipid-altering effects of ezetimibe/simvastatin (EZE/SIMVA) co-administered with fenofibrate (FENO) in mixed hyperlipidemic patients with (MetS) versus those without MetS. METHODS:A total of 611 patients, 20 to 79 years old, with LDL-C 130-220 mg/dL (100-180 mg/dL for patients with type 2 di...

journal_title：Metabolic syndrome and related disorders

authors： Gil-Extremera B,Mendez G,Zakson M,Meehan A,Shah A,Lin J,Mitchel Y

更新日期：2007-12-01 00:00:00

abstract：: Background: Ethnic variations have been reported in allelic frequencies of the leptin receptor gene (LEPR) with population-specific effects. We aimed to explore the association of LEPR polymorphisms with obesity, metabolic syndrome (MetS), and leptin levels in Afro-Caribbe...

journal_title：Metabolic syndrome and related disorders

authors： Foucan L,Bassien-Capsa V,Rambhojan C,Lacorte JM,Larifla L

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess clinical and inflammatory markers in nonalcoholic fatty liver disease (NAFLD) in postmenopausal women with metabolic syndrome. METHODS:This cross-sectional study included 180 Brazilian women (age ≥45 years and amenorrhea ≥12 months). Metabolic syndrome was diagnosed by th...

journal_title：Metabolic syndrome and related disorders

authors： Rodrigues MH,Bruno AS,Nahas-Neto J,Sandrim VC,Muniz LG,Nahas EA

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is strongly associated to oxidative stress, metabolic syndrome, and cardiovascular risk. Hepatocytes overloaded with fatty acids (FA) could generate substances that interfere with endothelial function, providing a potential explanation for this association. We have in...

journal_title：Metabolic syndrome and related disorders

authors： Soardo G,Donnini D,Domenis L,Catena C,De Silvestri D,Cappello D,Dibenedetto A,Carnelutti A,Bonasia V,Pagano C,Sechi LA

更新日期：2011-10-01 00:00:00

abstract：AIM:The objective of this study was to estimate basal insulin resistance (IR) and insulin secretion (IS) in Nigerians with type 2 diabetes mellitus (T2DM). METHODS:The homeostasis model assessment (HOMA) method was used to estimate basal IR and IS in 146 Nigerians with T2DM and in 33 controls at the University of Nige...

journal_title：Metabolic syndrome and related disorders

authors： Oli JM,Adeyemo AA,Okafor GO,Ofoegbu EN,Onyenekwe B,Chukwuka CJ,Onwasigwe CN,Ufelle S,Chen G,Rotimi CN

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess prevalence of metabolic syndrome and its components according to different criteria in the population of bank employees in St. Petersburg, Russia. METHODS:A total of 1,600 office workers were screened at their working places from the Sberbank state bank in St. Petersburg....

journal_title：Metabolic syndrome and related disorders

authors： Konradi AO,Rotar OP,Korostovtseva LS,Ivanenko VV,Solntcev VN,Anokhin SB,Bart VA,Shlyakhto EV

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Niacin increases blood glucose, but whether the degree of increase is associated with increasing body mass index (BMI) is unknown. We evaluated the effect of extended-release niacin initiation on fasting plasma glucose (FPG) and the development of new-onset diabetes mellitus (DM) in relation to body mass ind...

journal_title：Metabolic syndrome and related disorders

authors： Libby A,Meier J,Lopez J,Swislocki AL,Siegel D

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:This study investigates ethnic disparities in metabolic syndrome in Malaysia. METHODS:Data were obtained from the Malaysia Non-Communicable Disease Surveillance-1 (2005/2006). Logistic regressions of metabolic syndrome health risks on sociodemographic and health-lifestyle factors were conducted using a mult...

journal_title：Metabolic syndrome and related disorders

authors： Tan AK,Dunn RA,Yen ST

更新日期：2011-12-01 00:00:00

abstract：: Background: The problem of obesity in young women leads to future chronic diseases, effects on reproductive health, and next-generation obesity. Thus, it is necessary to provide effective support for these women's behavioral change. The purpose of this study was to evaluat...

journal_title：Metabolic syndrome and related disorders

authors： Nishimura A,Harashima SI,Hosoda K,Honda I

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Fibronectin type III domain containing 5 (FNDC5) and its protein product Irisin are therapeutic targets for obesity-associated disorders. Irisin plays an important role in energy regulation, inducing browning of white adipocytes, and improving obesity. We aimed to investigate the association between muscle I...

journal_title：Metabolic syndrome and related disorders

authors： de Macêdo SM,Lelis DF,Mendes KL,Fraga CAC,Brandi IV,Feltenberger JD,Farias LC,Guimarães ALS,de Paula AMB,Santos SHS

更新日期：2017-05-01 00:00:00

abstract：:Even though insulin resistance, cardiovascular disease (CVD), and type 2 diabetes (T2D) are associated with hypertriglyceridemia, blacks with these conditions usually have normal triglyceride (TG) levels. This is often called a lipid paradox. More precisely, it is a "TG paradox." The pathways that lead to hypertriglyc...

journal_title：Metabolic syndrome and related disorders

authors： Yu SS,Castillo DC,Courville AB,Sumner AE

更新日期：2012-04-01 00:00:00

abstract：:The metabolic syndrome (MS) is a clustering of cardiovascular risk factors, with insulin resistance as a major feature. This syndrome has been variously defined, but generally consists of 3 or more of the following components: hyperglycemia, hypertension, hypertriglyceridemia, low HDL, and increased abdominal circumfe...

journal_title：Metabolic syndrome and related disorders

authors： Sutherland JP,McKinley B,Eckel RH

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:In the fed state, the glucose disposal action of insulin can be attributed in approximately equal part to the direct action of insulin and to a hepatic insulin sensitizing substance (HISS) that acts selectively on skeletal muscle. HISS action is absent in the 24-hour fasted state. The objective of this study...

journal_title：Metabolic syndrome and related disorders

authors： Lautt WW,Legare DJ,Reid MA,Sadri P,Ting JW,Prieditis H

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Obesity and metabolic syndrome are significant global health issues, with current public health messages predominately focused on altering dietary and physical activity behaviors. Resveratrol is a polyphenol (stilbenoid) commonly found in grapes, and human trials to date have shown conflicting and limited be...

journal_title：Metabolic syndrome and related disorders

authors： Christenson J,Whitby SJ,Mellor D,Thomas J,McKune A,Roach PD,Naumovski N

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The use of chromium-containing dietary supplements is widespread among patients with type 2 diabetes. Chromium's effects in patients at high risk for developing diabetes, especially those with metabolic syndrome, is unknown. The objective of this study was to determine the effects of chromium picolinate (CrP...

journal_title：Metabolic syndrome and related disorders

authors： Iqbal N,Cardillo S,Volger S,Bloedon LT,Anderson RA,Boston R,Szapary PO

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Isolated postchallenge hyperglycemia (IPH) is an early form of type 2 diabetes with fasting glucose <126 mg/dL and 2-hr postchallenge glucose ≥200 mg/dL. The purpose of this study was to explore the relationships of high-sensitivity C-reactive protein (hsCRP) with IPH. METHODS:We recruited 476 naturally pos...

journal_title：Metabolic syndrome and related disorders

authors： Hwu CM,Lin YC,Lin MW

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The increased prevalence of overweight and obesity has reached alarming proportions worldwide and has serious health implications, including an association with an increase in metabolic syndrome. Among the methods to control metabolic syndrome, bariatric surgery plays an important role and can provide a sign...

journal_title：Metabolic syndrome and related disorders

authors： Saboya C,Arasaki CH,Matos D,Lopes-Filho GJ

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:In contrast to the definition of metabolic syndrome (MetS) in adults, there is no standard definition of MetS in pediatric populations. We aimed at assessing the differences in the prevalence of MetS in children and adolescents aged 9-17 years using four different operational definitions for these age groups...

journal_title：Metabolic syndrome and related disorders

authors： Ramírez-Vélez R,Anzola A,Martinez-Torres J,Vivas A,Tordecilla-Sanders A,Prieto-Benavides D,Izquierdo M,Correa-Bautista JE,Garcia-Hermoso A

更新日期：2016-11-01 00:00:00

abstract：: Background: Obesity causes significant morbidity and mortality and continues to be a significant public health concern. Unfortunately, lifestyle modification and pharmacotherapy do not produce durable results. This has led to bariatric surgical procedures playing an increa...

journal_title：Metabolic syndrome and related disorders

authors： Kittah E,Camilleri M,Jensen MD,Vella A

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:Obesity and high body fat are related to diabetes and metabolic syndrome (MetS) in all ethnic groups. Based on the International Diabetes Federation (IDF) definition of MetS, the aim of the present study was to compare body adiposity indexes (BAIs) and to assess their various cutoff values for the prediction of...

journal_title：Metabolic syndrome and related disorders

authors： Correa-Bautista JE,González-Ruíz K,Vivas A,Triana-Reina HR,Martínez-Torres J,Prieto-Benavides DH,Carrillo HA,Ramos-Sepúlveda JA,Afanador-Rodríguez MI,Villa-González E,García-Hermoso A,Ramírez-Vélez R

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The fetal origins hypothesis indicates that morphometric evidence of fetal nutritional deprivation is predictive of excessive weight gain/obesity, insulin resistance, and cardiovascular disease after birth. However, it is unclear whether these effects are present in offspring with "normal" birth weights in c...

journal_title：Metabolic syndrome and related disorders

authors： Clapp Iii JF,Lopez B

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Previous reports showed a high prevalence of obesity, diabetes, hypertension, and dyslipidemia among people suffering from posttraumatic stress disorder (PTSD). However, there is a lack of reviews that systematically analyze the relationship between PTSD and metabolic syndrome. We conducted a systematic revi...

journal_title：Metabolic syndrome and related disorders

authors： Bartoli F,Carrà G,Crocamo C,Carretta D,Clerici M

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Obesity and metabolic syndrome (MetS) are increasing rapidly worldwide, but metabolically healthy population exists. Thus, this study evaluated the proportion of obesity and MetS and investigated clinical and body compositional factors associated with MetS in obese Koreans. METHODS:This cross-sectional obse...

journal_title：Metabolic syndrome and related disorders

authors： Kim YM,Kim S,Kim SH,Won YJ

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The relationship between the metabolic syndrome and subclinical atherosclerosis among elderly people remains controversial. We seek to investigate the associations of metabolic syndrome and its components with subclinical carotid atherosclerosis in older people living in rural China. METHODS:This cross-sect...

journal_title：Metabolic syndrome and related disorders

authors： Yan Z,Liang Y,Jiang H,Cai C,Sun B,Qiu C

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The combination of ezetimibe and simvastatin (EZE/SIMVA) inhibits intestinal absorption and hepatic synthesis of cholesterol, providing significantly greater LDL-C-lowering compared to either drug alone. We examined the efficacy and safety of EZE/SIMVAin hypercholesterolemic patients with metabolic syndrome ...

journal_title：Metabolic syndrome and related disorders

authors： Feldman T,Ose L,Shah A,Zakson M,Meehan A,Johnson-Levonas AO,Maccubbin D,Tribble DL,Veltri E,Mitchel Y

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:Patients with metabolic syndrome are at increased risk of atherosclerotic coronary heart disease, often have mixed dyslipidemia, and may thus require more aggressive treatment of multiple lipid parameters. The objective of this investigation was to compare the treatment response of ezetimibe co-administered w...

journal_title：Metabolic syndrome and related disorders

authors： Bays HE,Shah A,Macdonell G,Taggart WV,Gumbiner B

更新日期：2011-04-01 00:00:00

abstract：: Background: Few studies have compared the local and international body mass index (BMI) reference sets for their relationship with metabolic syndrome (MetS) in children. This study aimed to compare the BMI percentiles using Korean, United States Centers for Disease Control...

journal_title：Metabolic syndrome and related disorders

authors： Lee K

更新日期：2019-05-01 00:00:00

abstract：INTRODUCTION:The association of metabolic syndrome with venous thromboembolism (VTE) remains uncertain. Moreover, the relevance of abdominal obesity as an independent or related risk factor for VTE in the metabolic syndrome cluster is controversial. We aimed to evaluate the impact of metabolic syndrome and its individu...

journal_title：Metabolic syndrome and related disorders

authors： Vayá A,Martínez-Triguero ML,España F,Todolí JA,Bonet E,Corella D

更新日期：2011-06-01 00:00:00

abstract：: Background: Glycated hemoglobin (HbA1c) is an index of the average blood glucose level over the preceding 2-3 months. In experimental studies, the lens responded to changes in osmolarity by forming vacuoles. By observing the vacuoles of the lens during eye examination, can...

journal_title：Metabolic syndrome and related disorders

authors： Koç Ş,Baysal S,Koç Z,Yener AÜ

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The circadian pattern of adipokines is blunted in obese subjects, and we tested the hypothesis that bariatric surgery could normalize the 24-hr pattern of adipokines. Therefore, this study was designed to examine the early impact of the newly designed sleeve gastrectomy with transit bipartition (SGTB) surger...

journal_title：Metabolic syndrome and related disorders

authors： Costa Justus JF,Ligocki Campos AC,Figueroa AL,Gomis R,Santo MA,Fávero GM,Milléo FQ,Vieira E

更新日期：2016-02-01 00:00:00