Abstract:
OBJECTIVE:We previously developed an 8-item self-assessment tool to identify individuals with a high probability of having albuminuria. This tool was developed and externally validated among non-Hispanic Whites and non-Hispanic Blacks. We sought to validate it in a multi-ethnic cohort that also included Hispanics and Chinese Americans. DESIGN:This is a cross-sectional study. SETTING:Data were collected using standardized questionnaires and spot urine samples at a baseline examination in 2000-2002. The 8 items in the self-assessment tool include age, race, gender, current cigarette smoking, history of diabetes, hypertension, or stroke, and self-rated health. PARTICIPANTS:Of 6,814 community-dwelling adults aged 45-84 years participating in the Multi-Ethnic Study of Atherosclerosis (MESA), 6,542 were included in the primary analysis. MAIN OUTCOME MEASURES:Albuminuria was defined as urine albumin-to-creatinine ratio ≥ 30 mg/g at baseline. RESULTS:Among non-Hispanic Whites, non-Hispanic Blacks, Hispanics, and Chinese Americans, the prevalence of albuminuria was 6.0%, 11.3%, 11.6%, and 10.8%, respectively. The c-statistic for discriminating participants with and without albuminuria was .731 (95% CI: .692, .771), .728 (95% CI: .687, .761), .747 (95% CI: .709, .784), and .761 (95% CI: .699, .814) for non-Hispanic Whites, non-Hispanic Blacks, Hispanics, and Chinese Americans, respectively. The self-assessment tool over-estimated the probability of albuminuria for non-Hispanic Whites and Blacks, but was well-calibrated for Hispanics and Chinese Americans. CONCLUSIONS:The albuminuria self-assessment tool maintained good test characteristics in this large multi-ethnic cohort, suggesting it may be helpful for increasing awareness of albuminuria in an ethnically diverse population.
journal_name
Ethn Disjournal_title
Ethnicity & diseaseauthors
Tanner RM,Woodward M,Peralta C,Warnock DG,Gutiérrez O,Shimbo D,Kramer H,Katz R,Muntner Pdoi
10.18865/ed.25.4.427subject
Has Abstractpub_date
2015-11-05 00:00:00pages
427-34issue
4eissn
1049-510Xissn
1945-0826pii
ed.25.4.427journal_volume
25pub_type
杂志文章abstract:OBJECTIVE:To identify the prevalence of hypertension among adults in Bo, Sierra Leone. DESIGN:Hypertension data were extracted from outpatient clinic records. SETTING:Mercy Hospital in urban Bo, Sierra Leone. PATIENTS:All nonpregnant outpatients aged -15 years seen at the outpatient clinic in 2009. MAIN OUTCOME MEA...
journal_title:Ethnicity & disease
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journal_title:Ethnicity & disease
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journal_title:Ethnicity & disease
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