Metabolomics: a state-of-the-art technology for better understanding of male infertility.

abstract：:Solasodine obtained from the Solanum xanthocarpum berries was administered to Rhesus monkeys for 150 days to evaluate their effect on testicular cell population dynamics. Solasodine brings about an interference with spermiogenesis at the stage XII of late spermatids. The spermatids were decreased by 69% (P less than 0...

journal_title：Andrologia

authors： Dixit VP,Gupta RS,Gupta S

更新日期：1989-11-01 00:00:00

abstract：:Male infertility is a major health problem worldwide. We investigated a possible association between leptin, obesity, hormonal interplay and male infertility. This cross-sectional study of 313 males (178 infertile and 135 fertile) was carried out in 2017. The subjects were categorised by body mass index (BMI) and body...

journal_title：Andrologia

authors： Amjad S,Baig M,Zahid N,Tariq S,Rehman R

更新日期：2019-02-01 00:00:00

abstract：:Varicocele is one of the leading causes of male infertility in which oxidative stress induces DNA damages in spermatozoa of patients with varicocele. Recent studies indicated that the treatment with antioxidant agents has protective effects against the formation of reactive oxygen species (ROS). Our research aimed to ...

journal_title：Andrologia

authors： Dolatkhah MA,Shokoohi M,Charvandeh S,Tvrda E,Shoorei H,Moghimian M,Alihemmati A

更新日期：2020-12-01 00:00:00

abstract：:The spontaneous acrosomal reaction of mouse spermatozoa during their passage through the male and female genital tract was studied by indirect immunofluorescence staining techniques using antibodies against the outer acrosomal membrane (OAM). Low rates of spontaneously acrosome-reacted spermatozoa could be observed du...

journal_title：Andrologia

authors： Klemm M,Engel W

更新日期：1991-11-01 00:00:00

abstract：:Considering dopamine-enhancing effect of (+)-catechin, the present study was designed to evaluate dopamine-2 (D2) receptor agonistic and phosphodiesterase-5 (PDE5) enzyme inhibitory effects in in silico and effect on male sexual function of Sprague Dawley rats in vivo. (+)-Catechin and standard (sildenafil and bromocr...

journal_title：Andrologia

authors： Rai A,Gill M,Kinra M,Dsouza LA,Sumalatha S,Raj S,Shetty R,Nandakumar K,Chamallamudi MR,Kumar N

更新日期：2020-07-02 00:00:00

abstract：:In sows, the oviductal sperm-binding glycoprotein (SBG), which binds to the periacrosomal region of boar sperm, has been shown to be involved in sperm selection. In this work, we isolated porcine sperm proteins that interact with SBG. One of them is identified as a homologue of human S100A7 (psoriasin). Anti-human S10...

journal_title：Andrologia

authors： Teijeiro JM,Marini PE

更新日期：2012-05-01 00:00:00

abstract：:This study aimed to evaluate the effect of N-acetyl cysteine on the male reproductive system and consensus and classification of data found from previous studies. It is undeniable that N-acetyl cysteine as a powerful antioxidant compound can medicate many diseases such as cardiovascular, kidney, liver and reproductive...

journal_title：Andrologia

authors： Ghafarizadeh A,Malmir M,Naderi Noreini S,Faraji T

更新日期：2021-02-01 00:00:00

abstract：:Aquaporin-9 (AQP-9) regulates tissue hydration by promoting transmembrane exchanges of both water and solutes, such as lactate. The latter is a key metabolite of primary spermatocytes and of maturing haploid germ cells (h-GCs). The present investigation was aimed at immunolocalising human AQP-9 in both normal and vari...

journal_title：Andrologia

authors： Arena S,Arena F,Maisano D,Di Benedetto V,Romeo C,Nicòtina PA

更新日期：2011-02-01 00:00:00

abstract：:The aim of this study was to investigate the effects of several dietary fatty acids (FAs) on semen quality and blood parameters in rams. We gave diet-supplemented treatments (35 g day(-1) ram(-1)) by C16:0 (palm oil), C18:2 [sunflower oil (SO)] and an n-3 source [fish oil (FO)] to 12 rams, who were fed for 15 weeks du...

journal_title：Andrologia

authors： Esmaeili V,Shahverdi AH,Alizadeh AR,Alipour H,Chehrazi M

更新日期：2014-02-01 00:00:00

abstract：:The role of N-methyl-D-aspartate (NMDA) and non-NMDA receptors in the control of FSH and LH secretion was analysed in prepubertal male rats. In the first experiment 4, 8, 12, 16, 20 and 30-day-old males were decapitated 15 min after vehicle, NMDA or kainic acid (KA) administration. In the second experiment, 23-day-old...

journal_title：Andrologia

authors： Aguilar E,Tena-Sempere M,Gonzalez D,Pinilla L

更新日期：1996-05-01 00:00:00

abstract：:The aim of this study was to investigate possible ultrasound seminal vesicle (SV) changes in infertile patients with 'hypertrophic-congestive' (HCUF) or 'fibro-sclerotic' (FSUF) ultrasound form of male accessory gland infection (MAGI) after prolonged administration of tadalafil (TAD), a selective phosphodiesterase-5 i...

journal_title：Andrologia

authors： La Vignera S

更新日期：2013-12-01 00:00:00

abstract：:The Aurora kinases regulate chromosome segregation and cytokinesis, and alterations in their expression associate with cell malignant transformation. In this study, we demonstrated by qRT-PCR analysis of 14 seminomas that Aurora-A mRNA was, with respect to control tissues, augmented in five of 14 tumour tissues by 2.1...

journal_title：Andrologia

authors： Baldini E,Arlot-Bonnemains Y,Mottolese M,Sentinelli S,Antoniani B,Sorrenti S,Salducci M,Comini E,Ulisse S,D'Armiento M

更新日期：2010-08-01 00:00:00

abstract：:5alpha-Dihydrotestosterone (DHT), the most powerful naturally occurring androgen, is commercially available since 1982 as a gel. In view of its considerably higher biopotency (three to six times) than of testosterone, side effects, particularly on the main target organ of androgens, the prostate, are anticipated. In f...

journal_title：Andrologia

authors： Sakhri S,Gooren LJ

更新日期：2007-12-01 00:00:00

abstract：:The present study summarizes a four-year follow-up of 20 production workers with D.B.C.P.-induced testicular dysfunction. In 4 of the 13 initially azoospermic men, sperm density increased to 1.5 to 48.0 millions/ml. Five of the seven initially oligozoospermic workers showed a marked increase in sperm count. In all the...

journal_title：Andrologia

authors： Potashnik G

更新日期：1983-03-01 00:00:00

abstract：:The authors present the histological features of the testes in 1,609 cases of male sterility. In 485 cases (30.1%), histological changes were found, which did not warrant treatment. The histologic pattern of the testes was normal in only 39% of the cases of azoospermia; and only these patients were qualified for surge...

journal_title：Andrologia

authors： Janczewski Z,Bablok L

更新日期：1978-09-01 00:00:00

abstract：:Semen samples of 24 patients were analysed. Volumes were measured and the numbers of progressively motile (PMS), motile (MS) and nonmotile spermatozoa (NMS) were determined. These 24 samples appeared to show a large variation in motility percentages and numbers. Spermatozoa of these semen samples were isolated from th...

journal_title：Andrologia

authors： Rhemrev JP,Vermeiden JP,Haenen GR,De Bruijne JJ,Rekers-Mombarg LT,Bast A

更新日期：2001-05-01 00:00:00

abstract：:This study examines the effect of melatonin on leptin-induced changes in transition of histone to protamine in adult rats during spermatogenesis. Twelve-week-old Sprague-Dawley rats were randomised into control, leptin-, leptin-melatonin-10-, leptin-melatonin-20- and melatonin-10-treated groups with six rats per group...

journal_title：Andrologia

authors： Almabhouh FA,Singh HJ

更新日期：2018-02-01 00:00:00

abstract：:Twenty infertile patients with normal tubal patency were inseminated intraperitoneally (11 once, seven twice, and two three times) with spermatozoa (mean 14 x 10(6), range 0.6-48 x 10(6)) prepared by the standard swim-up technique. The occurrence of immunization to spermatozoa was looked for by the Gelatin Agglutinati...

journal_title：Andrologia

authors： Ragni G,Lenzi A,Gandini L,Cristiani C,Lombroso GC,Olivares MD,Wyssling H,Dondero F,Crosignani PG

更新日期：1993-01-01 00:00:00

abstract：:Seminal oxidative stress plays an important role in male factor infertility (MFI), worldwide. A study was thus undertaken for the first time to establish seminal reactive oxygen species (ROS) as a clinical marker of MFI in a cohort of Sri Lankan males. The nitro blue tetrazolium (NBT) assay for ROS estimation and modi...

journal_title：Andrologia

authors： Amarasekara DS,Wijerathna S,Fernando C,Udagama PV

更新日期：2014-03-01 00:00:00

abstract：:In eutherian mammalian spermatozoa the capacitation is coupled to a specific type of metabolism, that is glycolysis or oxidative respiration. A cytochemical study was carried out on cytochrome oxidase and lactate dehydrogenase in human spermatozoa collected at different times during in vitro capacitation. Human sperma...

journal_title：Andrologia

authors： Ferrandi B,Lange Consiglio A,Chiara F,Uber E,Marchini M,Baglioni A,Carnevali A,Cremonesi F,Porcelli F

更新日期：1987-06-01 00:00:00

abstract：:Neuropeptide Y (NPY) has been shown to induce contraction of isolated human penile erectile tissue and potentiate the response to noradrenaline. The purpose of our study was to measure in the cavernous and systemic blood of healthy male volunteers the course of NPY through different stages of sexual arousal. Whole blo...

journal_title：Andrologia

authors： Ückert S,Soyk L,Trottmann M,Stief CG,Kuczyk MA,Becker AJ

更新日期：2012-05-01 00:00:00

abstract：:This short review summarizes some recent findings on arylhydrocarbon (dioxin) receptor expression during early pregnancy in mammals. The arylhydrocarbon receptor is a ligand-activated transcription factor and was originally described as a mediator of the toxic effects of dioxins and other chlorinated hydrocarbons such...

journal_title：Andrologia

authors： Fischer B

更新日期：2000-09-01 00:00:00

abstract：:Administration of indomethacin exhibited antigonadal action by inhibiting the Leydig cells, sex-accessories and spermatocyte-spermatid conversion process. Administration of PGE2 or PGF2 alpha had no effect on Leydig cell nuclear volume or accessory organ weights, but PGE2 had a restorative effect on the efficiency of ...

journal_title：Andrologia

authors： Sanyal S,Patra PB,Nag S,Biswas NM

更新日期：1980-03-01 00:00:00

abstract：:Twisting of the spermatic cord is considered a popular problem in the urological field, which may lead to testicular necrosis and male infertility. Sitagliptin, a glucose-lowering agent, proved to have a vindicatory function in myocardial and renal ischaemia/reperfusion (I/R), but its role in testicular I/R has not ye...

journal_title：Andrologia

authors： Abdel-Aziz AM,Naguib Abdel Hafez SM

更新日期：2020-03-01 00:00:00

abstract：:We investigated whether chronic stress, applied from prepuberty to early puberty, interferes with the spermatogenic and androgenic testicular functions. Male pubertal rats (40 days old) were immobilized 6 h per day for 15 days. Plasma concentrations of corticosterone, prolactin and testosterone were significantly augm...

journal_title：Andrologia

authors： Almeida SA,Petenusci SO,Franci JA,Rosa e Silva AA,Carvalho TL

更新日期：2000-01-01 00:00:00

abstract：:Infertility affects up to 15% of reproductive-aged couples worldwide, with male factor being detected in 40%-50% of the cases. Proper sperm production is associated with the establishment of appropriate epigenetic marks in developing germ cells. Several studies have demonstrated the association between abnormal sperma...

journal_title：Andrologia

authors： Nasri F,Gharesi-Fard B,Namavar Jahromi B,Farazi-Fard MA,Banaei M,Davari M,Ebrahimi S,Anvar Z

更新日期：2017-12-01 00:00:00

abstract：:For the 13 abnormalities under consideration, the mean percentages were found to be the following: irregular head (15.2), microcephalic (9.8), elongated head (5.9), coiled tail (5.8), bent tail (4.7), thin head (4.6), cytoplasmic remains (3.2), macrocephalic (1.6), short tail (1.1), no tail (0.6), duplicate tail (0.5)...

journal_title：Andrologia

authors： Schwartz D,Mayaux MJ,Guihard-Moscato ML,Spira A,Jouannet P,Czyglik F,David G

更新日期：1984-09-01 00:00:00

abstract：:Penile amputation is an uncommon condition for which immediate surgical replantation is warranted. This work aimed to represent intervention and management for an amputated penis by replantation and reconstruction. A 23-year-old man presented with traumatic penile amputation for 2 h where the penile proximal part was ...

journal_title：Andrologia

authors： Salem HK,Mostafa T

更新日期：2009-08-01 00:00:00

abstract：:Angiotensin converting enzyme (EC 3.4.15.1) from bovine seminal plasma was shown to exist in two distinct forms. A lower molecular weight form of the enzyme having higher activity was purified to homogeneity. Final recovery of the enzyme was 18.37%. The apparent molecular weight of the enzyme was estimated to be 1.99 ...

journal_title：Andrologia

authors： Sharma M,Singh US

更新日期：1991-07-01 00:00:00

abstract：:Androgen insensitivity syndrome (AIS) is an X-linked disorder due to mutations of androgen receptor (AR) gene. Various AR mutations have been identified, and the characterisation of these mutations greatly facilitates our understanding of AR structure-function. In this study, we have analysed an AR missense mutation (...

journal_title：Andrologia

authors： Cai J,Cai LQ,Hong Y,Zhu YS

更新日期：2012-05-01 00:00:00