Shearing of the CENP-A dimerization interface mediates plasticity in the octameric centromeric nucleosome.

abstract：:We investigate the impact of borders on the topology of spatially embedded networks. Indeed territorial subdivisions and geographical borders significantly hamper the geographical span of networks thus playing a key role in the formation of network communities. This is especially important in scientific and technologi...

journal_title：Scientific reports

authors： Cerina F,Chessa A,Pammolli F,Riccaboni M

更新日期：2014-04-01 00:00:00

abstract：:The animal gut microbiota evolves quickly towards a complex community and plays crucial roles in its host's health and development. Factors such as host genetics and environmental changes are regarded as important for controlling the dynamics of animal gut microbiota. Migratory animals are an important group for study...

journal_title：Scientific reports

authors： Le MH,Wang D

更新日期：2020-05-05 00:00:00

abstract：:Fossils of the sponge Angulosuspongia sinensis from calcareous mudstones of the middle and upper part of the Kaili Formation (Cambrian Stage 5) in the Jianhe area of Guizhou province, South China, exhibit an apparently reticulate pattern, characteristic of the Vauxiidae. Energy Dispersive X-Ray Spectrometry (EDS) and ...

journal_title：Scientific reports

authors： Yang XL,Zhao YL,Babcock LE,Peng J

更新日期：2017-02-21 00:00:00

abstract：:Detailed structural analyses of the mushroom body which plays critical roles in olfactory learning and memory revealed that it is directly connected with multiple primary sensory centers in Drosophila. Connectivity patterns between the mushroom body and primary sensory centers suggest that each mushroom body lobe proc...

journal_title：Scientific reports

authors： Yagi R,Mabuchi Y,Mizunami M,Tanaka NK

更新日期：2016-07-11 00:00:00

abstract：:Intrahepatic cholestasis induced by drug toxicity, bile salt export pump (BSEP) deficiency, or pregnancy frequently causes cholestatic liver damage, which ultimately may lead to liver fibrosis and cirrhosis. Here, the preventive and therapeutic effects of peroxisome proliferator-activated receptor α (PPARα) signaling ...

journal_title：Scientific reports

authors： Zhao Q,Yang R,Wang J,Hu DD,Li F

更新日期：2017-08-30 00:00:00

abstract：:Although Hepatitis B virus (HBV) X gene mutations are frequently detected in HBV-related human hepatocellular carcinoma (HCC) patients, causative HBx mutations in the development of HCC have not yet been determined. We herein identified C1485T and C1653T mutations in the HBx gene as independent risk of HCC for HBV thr...

journal_title：Scientific reports

authors： Hagiwara S,Nishida N,Park AM,Komeda Y,Sakurai T,Watanabe T,Kudo M

更新日期：2017-09-05 00:00:00

abstract：:The first choice of treatment for patients with plantar fasciitis is non-invasive treatment, rather than corticosteroid injection (CSI). However, no comprehensive study has compared the effectiveness of CSI with non-invasive treatments for plantar fasciitis. We conducted a meta-analysis comparing CSI and non-invasive ...

journal_title：Scientific reports

authors： Chen CM,Lee M,Lin CH,Chang CH,Lin CH

更新日期：2018-03-05 00:00:00

abstract：:The first instar larva of a species of the Australian endemic genus Aenigmetopia Malloch is described for the first time, along with the first instar larvae of three other Australian species representing the genera Amobia Robineau-Desvoidy and Protomiltogramma Townsend. Larval morphology was analysed using a combinati...

journal_title：Scientific reports

authors： Szpila K,Walczak K,Johnston NP,Pape T,Wallman JF

更新日期：2021-01-29 00:00:00

abstract：:The neural bases of the inter-trial validity/invalidity sequential effects in a visuo-auditory modified version of the Central Cue Posner's Paradigm (CCPP) are analyzed by means of Early Directing Attention Negativity (EDAN), Contingent Negative Variation (CNV) and Lateralized Readiness Potential (LRP). ERPs results i...

journal_title：Scientific reports

authors： Arjona A,Escudero M,Gómez CM

更新日期：2014-03-31 00:00:00

abstract：:Group-IVa elements silicon and germanium are known for their semiconducting properties at room temperature, which are technologically critical. Metallicity and superconductivity are found at higher pressures only, Ge β-tin (tI4) being the first high-pressure metallic phase in the phase diagram. However, recent experim...

journal_title：Scientific reports

authors： Selli D,Baburin IA,Martoňák R,Leoni S

更新日期：2013-01-01 00:00:00

abstract：:Beta amyloid peptides (Aβ) are known risk factors involved in cognitive impairment, neuroinflammatory and apoptotic processes in Alzheimer's disease (AD). Phosphodiesterase 2 (PDE2) inhibitors increase the intracellular cAMP and/or cGMP activities, which may ameliorate cognitive deficits associated with AD. However, i...

journal_title：Scientific reports

authors： Wang L,Xiaokaiti Y,Wang G,Xu X,Chen L,Huang X,Liu L,Pan J,Hu S,Chen Z,Xu Y

更新日期：2017-09-21 00:00:00

abstract：:Single-cell RNA-seq has been established as a reliable and accessible technique enabling new types of analyses, such as identifying cell types and studying spatial and temporal gene expression variation and change at single-cell resolution. Recently, single-cell RNA-seq has been applied to developing embryos, which of...

journal_title：Scientific reports

authors： Ilsley GR,Suyama R,Noda T,Satoh N,Luscombe NM

更新日期：2020-03-18 00:00:00

abstract：:Single-photon emitters with stable and uniform photoluminescence properties are important for quantum technology. However, in many cases, colour centres in diamond exhibit spectral diffusion and photoluminescence intensity fluctuation. It is therefore essential to investigate the dynamics of colour centres at the sing...

journal_title：Scientific reports

authors： Liu Y,Chen G,Rong Y,McGuinness LP,Jelezko F,Tamura S,Tanii T,Teraji T,Onoda S,Ohshima T,Isoya J,Shinada T,Wu E,Zeng H

更新日期：2015-07-23 00:00:00

abstract：:Krüppel-like factor 6 (KLF6) is a transcription factor and tumor suppressor. We previously identified KLF6 as mediator of hepatocyte glucose and lipid homeostasis. The loss or reduction of KLF6 is linked to the progression of hepatocellular carcinoma, but its contribution to liver regeneration and repair in acute live...

journal_title：Scientific reports

authors： Sydor S,Manka P,Best J,Jafoui S,Sowa JP,Zoubek ME,Hernandez-Gea V,Cubero FJ,Kälsch J,Vetter D,Fiel MI,Hoshida Y,Bian CB,Nelson LJ,Moshage H,Faber KN,Paul A,Baba HA,Gerken G,Friedman SL,Canbay A,Bechmann LP

更新日期：2017-08-14 00:00:00

abstract：:The sustainable use of common pool resources has become a significant global challenge. It is now widely accepted that specific mechanisms such as community-based management strategies, institutional responses such as resource privatization, information availability and emergent social norms can be used to constrain i...

journal_title：Scientific reports

authors： Osten FBV,Kirley M,Miller T

更新日期：2017-05-23 00:00:00

abstract：:Honokiol, derived from Magnolia officinalis, has various pharmacological properties. Platelet activation plays a critical role in cardiovascular diseases. Honokiol has been reported to inhibit collagen-stimulated rabbit platelet aggregation. However, detailed further studies on the characteristics and functional activ...

journal_title：Scientific reports

authors： Lee TY,Chang CC,Lu WJ,Yen TL,Lin KH,Geraldine P,Li JY,Sheu JR

更新日期：2017-01-05 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron loss that ultimately leads to fatal paralysis. Reducing levels or function of the tyrosine kinase, ephrin type-A receptor 4 (EphA4), has been suggested as a potential approach for slowing disease progression in ALS. Becaus...

journal_title：Scientific reports

authors： Dominguez SL,Earr T,Dourado M,Ngu H,Meilandt WJ,Hanson JE

更新日期：2020-09-24 00:00:00

abstract：:We report a daily-updated sequenced/species Tree Of Life (sTOL) as a reference for the increasing number of cellular organisms with their genomes sequenced. The sTOL builds on a likelihood-based weight calibration algorithm to consolidate NCBI taxonomy information in concert with unbiased sampling of molecular charact...

journal_title：Scientific reports

authors： Fang H,Oates ME,Pethica RB,Greenwood JM,Sardar AJ,Rackham OJ,Donoghue PC,Stamatakis A,de Lima Morais DA,Gough J

更新日期：2013-01-01 00:00:00

abstract：:As part of efforts to reduce pressure on the Amazon and other biomes, one approach considered by Brazilian authorities and scientists is more intensive use of the soils of the interior of the northeast of the country, which are generally sandy, with low contents of organic matter and low water holding capacity and are...

journal_title：Scientific reports

authors： Batista EMCC,Shultz J,Matos TTS,Fornari MR,Ferreira TM,Szpoganicz B,de Freitas RA,Mangrich AS

更新日期：2018-07-16 00:00:00

abstract：:N(1)-methyladenosine (m(1)A) is a prominent RNA modification involved in many biological processes. Accurate identification of m(1)A site is invaluable for better understanding the biological functions of m(1)A. However, limitations in experimental methods preclude the progress towards the identification of m(1)A site...

journal_title：Scientific reports

authors： Chen W,Feng P,Tang H,Ding H,Lin H

更新日期：2016-08-11 00:00:00

abstract：:Replacing precious and nondurable Pt catalysts with cheap materials is a key issue for commercialization of fuel cells. In the case of oxygen reduction reaction (ORR) catalysts for direct methanol fuel cell (DMFC), the methanol tolerance is also an important concern. Here, we develop AlN nanowires with diameters of ab...

journal_title：Scientific reports

authors： Lei M,Wang J,Li JR,Wang YG,Tang HL,Wang WJ

更新日期：2014-08-11 00:00:00

abstract：:Hypertension is a public health issue in Iran. The study aimed to estimate the prevalence, awareness, treatment, and control of hypertension, and to explore their determinants among 10,040 Kurdish adults from Ravansar Non-Communicable Disease (RaNCD) cohort study in Iran. Univariate, and multivariate analyses were use...

journal_title：Scientific reports

authors： Rajati F,Hamzeh B,Pasdar Y,Safari R,Moradinazar M,Shakiba E,Bazargan-Hejazi S,Karim H,Najafi F

更新日期：2019-08-27 00:00:00

abstract：:The activation and regulation of coagulation Factor XIII (FXIII) protein has been the subject of active research for the past three decades. Although discrete evidence exists on various aspects of FXIII activation and regulation a combinatorial structure/functional view in this regard is lacking. In this study, we pre...

journal_title：Scientific reports

authors： Gupta S,Biswas A,Akhter MS,Krettler C,Reinhart C,Dodt J,Reuter A,Philippou H,Ivaskevicius V,Oldenburg J

更新日期：2016-07-25 00:00:00

abstract：:Hydrogen has therapeutic and preventive effects against various diseases. Although animal and clinical studies have reported promising results, hydrogen distribution in organs after administration remains unclear. Herein, the sequential changes in hydrogen concentration in tissues over time were monitored using a high...

journal_title：Scientific reports

authors： Yamamoto R,Homma K,Suzuki S,Sano M,Sasaki J

更新日期：2019-02-04 00:00:00

abstract：:Molecular behaviour of liquid water under proton irradiation is of great importance to a number of technological and medical applications. The highly energetic proton generates a time-varying field that is highly localized and heterogeneous at the molecular scale, and massive electronic excitations are produced as a r...

journal_title：Scientific reports

authors： Reeves KG,Kanai Y

更新日期：2017-01-13 00:00:00

abstract：:Developing effective treatment strategies for neurodegenerative diseases require an understanding of the underlying cellular pathways that lead to neuronal vulnerability and progressive degeneration. To date, numerous mutations in 147 distinct genes are identified to be "associated" with, "modifier" or "causative" of ...

journal_title：Scientific reports

authors： Dervishi I,Gozutok O,Murnan K,Gautam M,Heller D,Bigio E,Ozdinler PH

更新日期：2018-10-03 00:00:00

abstract：:Insulin secretion from pancreatic beta-cells is dependent on zinc ions as essential components of insulin crystals, zinc transporters are thus involved in the insulin secretory process. Zip14 (SLC39a14) is a zinc importing protein that has an important role in glucose homeostasis. Zip14 knockout mice display hyperinsu...

journal_title：Scientific reports

authors： Maxel T,Smidt K,Petersen CC,Honoré B,Christensen AK,Jeppesen PB,Brock B,Rungby J,Palmfeldt J,Larsen A

更新日期：2019-06-13 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Koo B,Koh CS,Park HY,Lee HG,Chang JW,Choi S,Shin HC

更新日期：2017-12-19 00:00:00

abstract：:In this report, we demonstrate mid-infrared dual-waveband (i.e., ~3 μm and ~2 μm) pulses from a cascaded gain-switched Ho3+-doped ZBLAN fiber laser by the use of hybrid pumping of 1150 nm CW and pulse LDs for the first time. Stable ~3 μm gain-switched pulses with the maximum output power 262.14 mW and shortest pulse d...

journal_title：Scientific reports

authors： Luo H,Li J,Zhu C,Lai X,Hai Y,Liu Y

更新日期：2017-12-04 00:00:00

abstract：:Microbiota-derived short-chain fatty acids (SCFAs) and organic acids produced by the fermentation of non-digestible fibre can communicate from the microbiome to host tissues and modulate homeostasis in mammals. The microbiome has circadian rhythmicity and helps the host circadian clock function. We investigated the ef...

journal_title：Scientific reports

authors： Tahara Y,Yamazaki M,Sukigara H,Motohashi H,Sasaki H,Miyakawa H,Haraguchi A,Ikeda Y,Fukuda S,Shibata S

更新日期：2018-01-23 00:00:00