Abstract:
:An outbreak of typhoid fever occurred in Chu-Tung township, Taiwan, with dates of onset from 6 July to 8 August, 1983. Fifty-four cases were hospitalized, of which 52 were laboratory confirmed. A chloramphenicol-resistant strain of Salmonella typhi was isolated from patients' blood samples. A community survey of 2772 people selected from 490 households by stratified systematic cluster sampling, presented an attack rate of 9.4 per 1000 and a case reporting rate of 10%. The attack rate was higher in males than females for persons younger than ten years, but was greater in females than in males aged 40 years and older. The only consistent characteristic of the early outbreak cases was drinking of tapwater (10/10, 100% versus 319/490, 65% of the controls). None of the early cases but 36% (13/36) of the late cases had drunk stream or river water. Households of early cases had better hygienic conditions than those of late cases. Laboratory examination of environmental specimens indicated Escherichia coli contamination of tapwater, well water and all stream foci associated with human activities. The epidemiological data combined with laboratory results suggested that the epidemic might be due to repeated contamination of some common source (such as municipal tapwater) and/or a variety of other vehicles.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
King CC,Chen CJ,You SL,Chuang YC,Huang HH,Tsai WCdoi
10.1093/ije/18.1.254subject
Has Abstractpub_date
1989-03-01 00:00:00pages
254-60issue
1eissn
0300-5771issn
1464-3685journal_volume
18pub_type
杂志文章abstract:Background:The Obstetrics and Periodontal Therapy (OPT) study, a randomized controlled trial, reported no effect of periodontal treatment on preterm birth. Even though there were more spontaneous abortions or stillbirths in the control group, sensitivity analyses using conventional approaches did not change the results...
journal_title:International journal of epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1093/ije/dyy089
更新日期:2018-10-01 00:00:00
abstract::A 10-year prospective study of Hawaii Japanese males with partial gastrectomy shows that the age-adjusted mortality rates in men with partial gastrectomy were slightly higher than in those with an intact stomach, but the difference failed to achieve statistical significance. This excess of mortality is due, in part, t...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/13.3.299
更新日期:1984-09-01 00:00:00
abstract::In recent years a strong case has been made in support of a viral aetiology for at least some primary hepatocellular carcinoma (PHC) in areas of low incidence. By pooling routinely collected cancer registration and infection data, study of the relationship between hepatitis B virus (HBV) infection and the incidence of...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.1.60
更新日期:1991-03-01 00:00:00
abstract::Using routinely collected maternity discharge data from 250,000 women in Scotland, we examined the risks of late spontaneous abortion and preterm delivery during the period 20 up to 36 weeks of gestation. Gestational age is treated as a fetal survival time and the risks of delivery associated with a history of spontan...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.2.456
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND:Few studies have examined the independent and combined relationships of body mass index (BMI) peak and rebound with adiposity, insulin resistance and metabolic risk later in life. We used data from Project Viva, a well-characterized birth cohort from Boston with repeated measures of BMI, to help fill this ga...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy286
更新日期:2019-02-01 00:00:00
abstract::This paper contains part of the results of a repetitive and comprehensive analysis of accidents among bus drivers. In a series of articles different aspects of the aetiology of bus drivers' accidents will be highlighted. The results presented indicate a strong negative association of experience with accident risk, mod...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/16.1.35
更新日期:1987-03-01 00:00:00
abstract::Recent criticism of epidemiologic methods has focused on the limitations of 'black box' epidemiology, a pejorative label given to the simple identification of exposure-disease relationships. The assessment of mediation is an important tool for addressing this criticism. By using mediation analysis to open the black bo...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyn372
更新日期:2009-06-01 00:00:00
abstract::We undertook a case-control study to investigate the association between chemicals in maternal drinking water consumed during pregnancy and congenital heart disease in the offspring. Two hundred and seventy affected children and 665 healthy children were enrolled in the study. Information on contaminant levels in mate...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/17.3.589
更新日期:1988-09-01 00:00:00
abstract::Life expectancy is most commonly measured for a period (corresponding to mortality within a given year) or for a specific birth cohort. Although widely used, period and cohort life expectancy have limitations as their time-trends often show disparities and can mask the historical mortality experience of all cohorts pr...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyz276
更新日期:2020-10-01 00:00:00
abstract::The European Prospective Investigation of Cancer (EPIC) is a 10-country collaborative study in which EPIC-Norfolk is one of the UK centres. EPIC-Norfolk examined 25 639 men and women resident in East Anglia (aged 40-79 years), between 1993 and 1997. The EPIC collaboration was set up to examine the dietary determinants...
journal_title:International journal of epidemiology
pub_type: 杂志文章
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更新日期:2014-08-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyh274
更新日期:2004-12-01 00:00:00
abstract::To develop a procedure for maximizing the discrimination of smoking status, the authors analysed parallel samples of thiocyanate and cotinine in serum, and carbon monoxide (CO) in expired air in a cohort of 145 male subjects aged 45-65 years. The sensitivity and specificity were 93% and 82%, 97% and 83%, and 98% and 1...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/21.3.488
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND:Neighbourhood socioeconomic status (SES) may affect rich and poor residents differentially. Two models are proposed. Model 1: living in a non-deprived neighbourhood is better for health because better collective material and social resources are available. Model 2: being poor (rich) relative to the neighbour...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyg084
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:To examine the effects, by income group, of targeted food taxes and subsidies on nutrition, health and expenditure in the UK. METHODS:A model based on consumption data and demand elasticity was constructed to predict the effects of four food taxation-subsidy regimens. Resulting changes in demand, expenditure...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyp214
更新日期:2009-10-01 00:00:00
abstract::The European Atherosclerosis Research Study--EARS--is a multicentre collaborative project sponsored by the European Community. Its main objective is to study, in young people, the biological expression of a paternal history of premature acute myocardial infarction (AMI) and the relative share of heredity and environme...
journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1093/ije/23.3.465
更新日期:1994-06-01 00:00:00
abstract::It is usually necessary to estimate repeatability of a self-administered questionnaire from responses by subjects on just two occasions. It is shown that it is not possible to estimate false positive and false negative classification rates separately, but that an average correct classification can be calculated. This ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/16.1.121
更新日期:1987-03-01 00:00:00
abstract::Serial blood specimens from Rh-negative pregnant women sent to laboratory for Rh antibody testing were stored and used for influenza investigations. The study period covered three epidemics, each caused by a different variant of influenza A (H3N2) virus. The relationship between pre-epidemic haemagglutination inhibiti...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/4.2.127
更新日期:1975-06-01 00:00:00
abstract:BACKGROUND:Little is known about long-term changes linking chronic diseases and poverty in low-income countries such as Bangladesh. This study examines how chronic disease mortality rates change across socioeconomic groups over time in Bangladesh, and whether such mortality is associated with households falling into po...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyv197
更新日期:2015-12-01 00:00:00
abstract::This paper discusses the application of Popper's philosophy to epidemiological research, examining in particular the problems of replication without risk of refutation, of mistaking statistical sophistication for deductive inference, and of dealing with causality at a general level. An example is given of a Popperian ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/4.3.159
更新日期:1975-09-01 00:00:00
abstract::The effects of smoking habits, socio-occupational factors and respiratory symptoms in the development of airflow obstruction have been studied in a working population of 575 men aged 30-54 in 1960 and surveyed in 1960 and 1972. On average, FEV1 decreased by 47 ml/annum. Apart from FEV1 level, which reflects loss since...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/8.3.201
更新日期:1979-09-01 00:00:00
abstract:BACKGROUND:The impact and cost-effectiveness of couples' voluntary HIV counselling and testing (CVCT) has not been quantified in real-world settings. We quantify cost-per-HIV-infection averted by CVCT in Zambia from the donor's perspective. METHODS:From 2010 to 2016, CVCT was established in 73 Zambian government clini...
journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:2019-02-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/23.1.98
更新日期:1994-02-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyw335
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Immunocompromised patients are at increased risk of acquiring healthcare-associated infections (HAIs) and often require specialized models of care. Surveillance of HAIs is essential for effective infection-prevention programmes. However, little is known regarding standardized or specific surveillance methods...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyz162
更新日期:2019-12-01 00:00:00
abstract::Cardiovascular disease risk factor and mortality data collected since the 1978 Conference on the Decline in Coronary Heart Disease Mortality were reviewed. Risk factor and disease trends were generally parallel and compatible with current hypotheses of cause and prevention. A few discrepancies between risk factors and...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-01-01 00:00:00
abstract::A comparative study of the effects of combined oral contraceptives (OC) on coagulation and fibrinolytic variables using standardized laboratory technique and methodology has been performed in Dublin (Ireland), Salvador (Brazil), Santiago (Chile) and Singapore. Of 777 entrants to the study, 622 were randomly allocated ...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1093/ije/20.4.913
更新日期:1991-12-01 00:00:00
abstract:BACKGROUND:In this paper we investigated whether the capture-recapture method is useful for a cancer registry to monitor its completeness of case ascertainment on a routine basis. METHODS:The capture-recapture method was used to estimate the completeness of case ascertainment in three regional cancer registries in the...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/23.6.1111
更新日期:1994-12-01 00:00:00
abstract::Two controlled, double blind field trials of a non-living promastigote vaccine against New World Cutaneous Leishmaniasis (NWCL) were conducted in 1981 and 1983 in Brazil. Brazilian Army conscripts were randomly assigned to the vaccine or placebo groups and tested during their training in the Amazon jungle, a high risk...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/ije/15.4.572
更新日期:1986-12-01 00:00:00
abstract::Data on T4 and TSH values derived from a voluntary screening programme of thyroid function in Belgium are presented. Significant differences in T4 values according to sex, maturity and birthplace are shown. ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/7.3.249
更新日期:1978-09-01 00:00:00
abstract:BACKGROUND:The long average incubation time from HIV infection to AIDS makes it difficult to estimate recent HIV transmission from AIDS incidence data. Age-period-cohort (APC) analysis can separate out the effects of age, calendar time and birth cohort to provide a clearer picture of transmission trends. METHODS:AIDS ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/28.6.1141
更新日期:1999-12-01 00:00:00