Efavirenz-based antiretroviral therapy versus nevirapine-including regimens for prevention of mother-to-child transmission of HIV option B plus in resource-limited settings: is there anything missing?

abstract：INTRODUCTION:Drug-resistant tuberculous meningitis has been reported worldwide. Isoniazid mono-resistance is the most frequent cause of drug-resistant tuberculous meningitis, a life-threatening disease. Extensive drug-resistant tuberculous meningitis has also been reported in some isolated case reports. Areas covered: ...

journal_title：Expert review of anti-infective therapy

authors： Garg RK,Rizvi I,Malhotra HS,Uniyal R,Kumar N

更新日期：2018-11-01 00:00:00

abstract：:The constant new emergence of life-threatening human respiratory viral pathogens presents new challenges to clinicians who are left with no available therapeutic interventions. Highly pathogenic strains of influenza A virus (IAV) share an enhanced capacity to propagate to the lower airways and paralyze alveolar macrop...

journal_title：Expert review of anti-infective therapy

authors： Coulombe F,Divangahi M

更新日期：2014-11-01 00:00:00

abstract：INTRODUCTION:Listeriosis is an uncommon foodborne infection that may cause moderate maternal illness, but can be extremely serious for the fetus and the newborn. Several guidelines have been elaborated in order to help clinicians on the care of pregnant women with known or suspected exposure to Listeria monocytogenes. ...

journal_title：Expert review of anti-infective therapy

authors： Pucci L,Massacesi M,Liuzzi G

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:The identification of factors that can predispose to the development of severe influenza is essential to enable the implementation of optimal prevention and control measures for vulnerable populations. AREAS COVERED:Unfortunately, data in the pediatric age group remain difficult to interpret. However, epi...

journal_title：Expert review of anti-infective therapy

authors： Principi N,Esposito S

更新日期：2016-10-01 00:00:00

abstract：:West Nile virus (WNV) is a mosquito-borne enveloped positive-strand RNA virus that emerged in North America in 1999 in New York City. Over the past 15 years, WNV has become established throughout the USA and has spread into Canada, Mexico and the Caribbean. CDC reports indicate >41,000 clinical cases, including more t...

journal_title：Expert review of anti-infective therapy

authors： Montgomery RR,Murray KO

更新日期：2015-03-01 00:00:00

abstract：:The true incidence of pulmonary bacterial coinfection in infants and children hospitalized with a viral respiratory infection is difficult to ascertain but can vary widely from under 1 to 44%. For the same patient group admitted to pediatric intensive care units and/or requiring ventilatory support, the evidence is mo...

journal_title：Expert review of anti-infective therapy

authors： Thorburn K,Riordan A

更新日期：2012-08-01 00:00:00

abstract：:Healthy children are high transmitters of influenza and can experience poor influenza outcomes. Many questions remain about the efficacy and impect of preventive measures because most existing studies report imprecise proxies of influenza incidence, do not follow subjects throughout the entire influenza season and acr...

journal_title：Expert review of anti-infective therapy

authors： Lee BY,Shah M

更新日期：2012-10-01 00:00:00

abstract：:Reviews the epidemiology, natural history and the current status of treatment of HIV/hepatitis B coinfection. ...

journal_title：Expert review of anti-infective therapy

authors： Benhamou Y

更新日期：2005-04-01 00:00:00

abstract：INTRODUCTION:Pneumocystis pneumonia is a potentially life-threatening pulmonary infection that occurs in immunocompromised individuals and HIV-infected patients with a low CD4 cell count. Trimethoprim-sulfamethoxazole has been used as the first-line agent for treatment, but mutations within dihydropteroate synthase gen...

journal_title：Expert review of anti-infective therapy

authors： Huang YS,Yang JJ,Lee NY,Chen GJ,Ko WC,Sun HY,Hung CC

更新日期：2017-09-01 00:00:00

abstract：INTRODUCTION:Syphilis continues to be a growing epidemic among men who have sex with men (MSM), particularly for those living with the human immunodeficiency virus (HIV). In 2016, MSM accounted for 80% of primary and secondary syphilis diagnoses in men in the United States; almost half of who were also HIV-infected. Th...

journal_title：Expert review of anti-infective therapy

authors： Refugio ON,Klausner JD

更新日期：2018-04-01 00:00:00

abstract：:As a consequence of antibiotic overuse and misuse, nosocomial infections caused by multidrug-resistant bacteria represent a physician's nightmare throughout the world. No newer antimicrobials active against Pseudomonas aeruginosa, the main multidrug-resistant nosocomial pathogen, are available or under investigation. ...

journal_title：Expert review of anti-infective therapy

authors： Giamarellou H

更新日期：2006-08-01 00:00:00

abstract：:Although efforts to combat the HIV epidemic have focused on the perinatal reduction of HIV transmission, many children are still being infected with HIV in resource-limited settings. Access to HIV care, cotrimoxazole and antiretroviral therapy (ART) for HIV-infected children has greatly improved in recent years, and h...

journal_title：Expert review of anti-infective therapy

authors： Callens SF,McKellar MS,Colebunders R

更新日期：2008-04-01 00:00:00

abstract：:Introduction: Among the multidrug resistant pathogens, extended-spectrum beta-lactamase (ESBL-E) or carbapenemase-producing Enterobacteriaceae (CPE) are currently considered the main threat due to the scarcity of therapeutic options and their rapid spread around the globe. In addition to developing new antibiotics and...

journal_title：Expert review of anti-infective therapy

authors： Catho G,Huttner BD

更新日期：2019-08-01 00:00:00

abstract：:Bacillus anthracis is the causative agent of anthrax, a disease that plagues both humans and various animal species. Effective vaccines are available, but those approved for human use are crude culture supernatants that require multiple injections and a yearly boost. Many experts agree that it is now time for the next...

journal_title：Expert review of anti-infective therapy

authors： Tournier JN,Ulrich RG,Quesnel-Hellmann A,Mohamadzadeh M,Stiles BG

更新日期：2009-03-01 00:00:00

abstract：:Five main groups of commercial assays for the multiplex detection of alpha human papillomaviruses (HPVs) are currently available. DNA-based screening assays, which test for the presence of 13-14 HPVs without determination of HPV type, have been the standard for HPV detection in the last decade. Assays that combine tes...

journal_title：Expert review of anti-infective therapy

authors： Poljak M,Kocjan BJ

更新日期：2010-10-01 00:00:00

abstract：:Inhaled antibiotics are not usually considered outside the setting of cystic fibrosis or Pneumocystis jiroveci prophylaxis. However, because they deliver high drug concentrations at the site of infection with negligible systemic absorption and toxicity, they are logical compliments to standard intravenous therapy for ...

journal_title：Expert review of anti-infective therapy

authors： Lesho E

更新日期：2005-06-01 00:00:00

abstract：INTRODUCTION:The emergence of carbapenem-resistant Enterobacteriaceae (CRE) has brought aminoglycosides to the frontline since an aminoglycoside may be the only antimicrobial to which CRE isolates show in vitro susceptibility. The appropriateness of aminoglycoside-based therapies for severe infections by CRE is discuss...

journal_title：Expert review of anti-infective therapy

authors： Zavascki AP,Klee BO,Bulitta JB

更新日期：2017-06-01 00:00:00

abstract：:Diarrhoea is one of the most commonly occurring diseases. This article presents a review of the current state of the treatment of acute infectious diarrhoea, as well as of the most important pathogens. The general principles of the therapy of diarrhoea are exemplified, followed by a description of the targeted antimic...

journal_title：Expert review of anti-infective therapy

authors： Lübbert C

更新日期：2016-01-01 00:00:00

abstract：:This report, completed in November 2003, is intended to serve as a resource for physicians, public health officials and organizations involved in the evaluation and treatment of Lyme disease. ...

journal_title：Expert review of anti-infective therapy

authors： Cameron D,Gaito A,Harris N,Bach G,Bellovin S,Bock K,Bock S,Burrascano J,Dickey C,Horowitz R,Phillips S,Meer-Scherrer L,Raxlen B,Sherr V,Smith H,Smith P,Stricker R,ILADS Working Group.

更新日期：2004-01-01 00:00:00

abstract：:The aim of this article is to review the current literature examining the use of procalcitonin-guided antibiotic therapy for management of chronic obstructive pulmonary disease (COPD) exacerbations. Procalcitonin is a serum marker that rises in response to bacterial infections, but remains low in nonbacterial infectio...

journal_title：Expert review of anti-infective therapy

authors： Tokman S,Schuetz P,Bent S

更新日期：2011-06-01 00:00:00

abstract：:Fluoroquinolones are an important group of antibiotics that are used widely in the treatment of various infectious diseases in adults as a result of their excellent spectrum of activity, significant tissue penetration and convenient routes of administration. Their use in children, however, has been limited until recen...

journal_title：Expert review of anti-infective therapy

authors： Velissariou IM

更新日期：2006-10-01 00:00:00

abstract：:Nosocomial infections are the most frequent complications observed in surgical patients. In colorectal surgery, the opening of the viscera causes the dissemination into the operative field of microorganisms originating from endogenous sources, increasing the chance of developing postoperative complications. It is repo...

journal_title：Expert review of anti-infective therapy

authors： Rovera F,Diurni M,Dionigi G,Boni L,Ferrari A,Carcano G,Dionigi R

更新日期：2005-10-01 00:00:00

abstract：:Chronic hepatitis C is a major worldwide health problem with an estimated prevalence of 1.6-2%. The prognosis of chronic hepatitis C depends on the rate of fibrosis progression which, over a 20-30-year time span, may determine the risk of developing cirrhosis and its complications, namely hepatocellular carcinoma, liv...

journal_title：Expert review of anti-infective therapy

authors： Aghemo A,Rumi MG,Colombo M

更新日期：2009-10-01 00:00:00

abstract：:In clinical practice, a significant proportion of HIV-infected patients receive lopinavir/ritonavir (LPV/r) as a component of highly active antiretroviral therapy (HAART). The study by Israr et al. was designed to evaluate the effects of the HIV protease inhibitor LPV/r on gingival epithelium growth and differentiatio...

journal_title：Expert review of anti-infective therapy

authors： Rivero A,Pérez-Camacho I

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:Carbapenem-resistant Enterobacterales (CRE) represent a global public health problem. Precision medicine (PM) is a multicomponent medical approach that should be used to individualize the management of patients infected with CRE. AREAS COVERED:Here, we differentiate carbapenem-producing CRE (CP-CRE) from ...

journal_title：Expert review of anti-infective therapy

authors： Reyes S,Nicolau DP

更新日期：2020-08-01 00:00:00

abstract：:Invasive candidiasis, including candidemia (IC/C), is a major cause of morbidity and mortality among hospitalized patients. While incidence is higher in intensive care units, the majority of cases of candidemia are documented in medical wards. Although Candida albicans is still the most frequently isolated species, IC...

journal_title：Expert review of anti-infective therapy

authors： Tagliaferri E,Menichetti F

更新日期：2015-06-01 00:00:00

abstract：INTRODUCTION:COVID-19 disease progresses through a number of distinct phases. The management of each phase is unique and specific. The pulmonary phase of COVID-19 is characterized by an organizing pneumonia with profound immune dysregulation, activation of clotting, and a severe microvascular injury culminating in seve...

journal_title：Expert review of anti-infective therapy

authors： Marik PE,Kory P,Varon J,Iglesias J,Meduri GU

更新日期：2020-08-18 00:00:00

abstract：:Influenza has circulated among humans for centuries and kills more people than many newly emerging diseases. The present methods for control of influenza are not adequate, especially for dealing with a pandemic. In the face of a rapidly spreading outbreak, a race to isolate the virus and prepare a vaccine would probab...

journal_title：Expert review of anti-infective therapy

authors： Epstein SL

更新日期：2003-12-01 00:00:00

abstract：:Bacteremias represent severe infectious complications following hematopoietic stem cell transplantation (HSCT). Frequency is highest during the pre-engraftment period, both in autologous and in allogeneic HSCT, when patients are granulocytopenic. In the postengraftment period, bacteremias are also frequent in the abse...

journal_title：Expert review of anti-infective therapy

authors： Castagnola E,Faraci M

更新日期：2009-06-01 00:00:00

abstract：:Telaprevir is an NS3/4A protease inhibitor that has recently received US FDA approval for the treatment of chronic HCV infection. Telaprevir is given in combination with peg-IFN-α and ribavirin and is indicated for both treatment-naive and treatment-experienced patients with genotype 1 infection. Along with the other ...

journal_title：Expert review of anti-infective therapy

authors： Muir AJ

更新日期：2011-12-01 00:00:00