HIV care and treatment for children in resource-limited settings.

abstract：:During the 2010 HIV Diagnostics Conference, which took place in Orlando (FL, USA) between 24 and 26 March 2010, salient new data related to three aspects of HIV testing (rapid point-of-care testing, laboratory assays and new technologies) were presented and discussed. A conundrum central to HIV diagnostics in the USA ...

journal_title：Expert review of anti-infective therapy

authors： Pandori MW,Branson BM

更新日期：2010-06-01 00:00:00

abstract：:The emergence of multidrug-resistant tuberculosis strains and the coinfection with HIV, together with advances in immunology, have led to renewed interest regarding ways to exploit the immune responses against Mycobacterium tuberculosis therapeutically. Here we review the fundamentals of tuberculosis therapy in view o...

journal_title：Expert review of anti-infective therapy

authors： Achkar JM,Casadevall A,Glatman-Freedman A

更新日期：2007-06-01 00:00:00

abstract：:In recent decades, the incidence of aspergillosis, candidiasis and clinically important deep mycoses has been increasing, with advances in transplantation medicine and anticancer chemotherapy. Micafungin (FK463, Fujisawa Healthcare) has been developed as a novel type of antifungal agent, which inhibits 1,3-beta-D-gluc...

journal_title：Expert review of anti-infective therapy

authors： Higashiyama Y,Kohno S

更新日期：2004-06-01 00:00:00

abstract：:Nosocomial infections are the most frequent complications observed in surgical patients. In colorectal surgery, the opening of the viscera causes the dissemination into the operative field of microorganisms originating from endogenous sources, increasing the chance of developing postoperative complications. It is repo...

journal_title：Expert review of anti-infective therapy

authors： Rovera F,Diurni M,Dionigi G,Boni L,Ferrari A,Carcano G,Dionigi R

更新日期：2005-10-01 00:00:00

abstract：:Carbapenem-resistant Klebsiella pneumoniae causes serious nosocomial infections and therapeutic options are limited. There is increasing evidence suggesting that combination antibiotic therapy is more effective than monotherapy and leads to better outcomes. However, questions remain about which regimen is optimal and ...

journal_title：Expert review of anti-infective therapy

authors： Watkins RR,Deresinski S

更新日期：2015-04-01 00:00:00

abstract：:Influenza has circulated among humans for centuries and kills more people than many newly emerging diseases. The present methods for control of influenza are not adequate, especially for dealing with a pandemic. In the face of a rapidly spreading outbreak, a race to isolate the virus and prepare a vaccine would probab...

journal_title：Expert review of anti-infective therapy

authors： Epstein SL

更新日期：2003-12-01 00:00:00

abstract：INTRODUCTION:The pathogenic and highly transmissible etiological agent, SARS-CoV-2, has caused a serious threat COVID-19 pandemic. WHO has declared the epidemic a public health emergency of international concern owing to its high contagiosity, mortality rate, and morbidity. Till now, there is no approved vaccine or dru...

journal_title：Expert review of anti-infective therapy

authors： Hossain MJ,Rahman SMA

更新日期：2020-12-23 00:00:00

abstract：:West Nile virus (WNV) is a mosquito-borne enveloped positive-strand RNA virus that emerged in North America in 1999 in New York City. Over the past 15 years, WNV has become established throughout the USA and has spread into Canada, Mexico and the Caribbean. CDC reports indicate >41,000 clinical cases, including more t...

journal_title：Expert review of anti-infective therapy

authors： Montgomery RR,Murray KO

更新日期：2015-03-01 00:00:00

abstract：INTRODUCTION:Patients with C. difficile infection (CDI) experience intestinal microflora changes that can promote the overgrowth and subsequent translocation of gut resident pathogens into the blood. Consistently, CDI due to PCR-ribotype 027 strain, severe or relapsing CDI, and treatment with high-dosage vancomycin are...

journal_title：Expert review of anti-infective therapy

authors： Falcone M,Venditti M,Sanguinetti M,Posteraro B

更新日期：2016-07-01 00:00:00

abstract：:Inflammation represents a complex biologic and biochemical process involving cells of the immune system and a plethora of biologic mediators in response to mechanical, chemical or infectious injuries. When mobilization of effector cells and molecules becomes excessive, the beneficial aspect of this response--to limit ...

journal_title：Expert review of anti-infective therapy

authors： Labro MT

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:The emergence of carbapenem-resistant Enterobacteriaceae (CRE) has brought aminoglycosides to the frontline since an aminoglycoside may be the only antimicrobial to which CRE isolates show in vitro susceptibility. The appropriateness of aminoglycoside-based therapies for severe infections by CRE is discuss...

journal_title：Expert review of anti-infective therapy

authors： Zavascki AP,Klee BO,Bulitta JB

更新日期：2017-06-01 00:00:00

abstract：:Sepsis in older adults has many challenges that affect rate of septic diagnosis, treatment, and monitoring parameters. Numerous age-related changes and comorbidities contribute to increased risk of infections in older adults, but also atypical symptomatology that delays diagnosis. Due to various pharmacokinetic/pharma...

journal_title：Expert review of anti-infective therapy

authors： Clifford KM,Dy-Boarman EA,Haase KK,Maxvill K,Pass SE,Alvarez CA

更新日期：2016-01-01 00:00:00

abstract：:Lymphatic filariasis (LF) is an important public health problem endemic in 73 countries, where it is a major cause of acute and chronic morbidity and a significant impediment to socioeconomic development. It is targeted for elimination by 2020, through preventive chemotherapy using albendazole in combination with eith...

journal_title：Expert review of anti-infective therapy

authors： Rebollo MP,Bockarie MJ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The coronavirus disease 2019 (COVID-19) pandemic has affected almost 2.5 million people worldwide with almost 170,000 deaths reported to date. So far, there is scarce evidence for the current treatment options available for COVID-19. Vitamin C has previously been used for treatment of severe sepsis and septi...

journal_title：Expert review of anti-infective therapy

authors： Hiedra R,Lo KB,Elbashabsheh M,Gul F,Wright RM,Albano J,Azmaiparashvili Z,Patarroyo Aponte G

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Listeriosis is an uncommon foodborne infection that may cause moderate maternal illness, but can be extremely serious for the fetus and the newborn. Several guidelines have been elaborated in order to help clinicians on the care of pregnant women with known or suspected exposure to Listeria monocytogenes. ...

journal_title：Expert review of anti-infective therapy

authors： Pucci L,Massacesi M,Liuzzi G

更新日期：2018-01-01 00:00:00

abstract：:Tuberculosis continues to be a major health problem worldwide, affecting millions of people each year. Accurate and rapid diagnosis is key to controlling the disease, yet the traditional tests for TB produce results that are either inaccurate or take too long to be definitive. A fast and reliable diagnostic method tha...

journal_title：Expert review of anti-infective therapy

authors： Al-Zamel FA

更新日期：2009-11-01 00:00:00

abstract：INTRODUCTION:Coronavirus Disease 2019 is a contagious infection that has infected millions worldwide. The objective of this systematic review is to identify studies pertaining to antivirals, both as sole and combined therapies, in COVID-19 patients and review the clinical outcomes of these treatment methods. AREAS COV...

journal_title：Expert review of anti-infective therapy

authors： Hussain N,Yoganathan A,Hewage S,Alom S,Harky A

更新日期：2020-10-20 00:00:00

abstract：INTRODUCTION:The nervous system is involved in 10-15% of patients infected with B. burgdorferi, B. afzelii and B. garinii. This review will address widespread misconceptions about the clinical phenomenology, diagnostic approach and response to treatment of neuroborreliosis. Areas covered: Improvements in diagnostic tes...

journal_title：Expert review of anti-infective therapy

authors： Halperin JJ

更新日期：2018-01-01 00:00:00

abstract：:Necrobacillosis, often used synonymously with Lemierre's syndrome, is a form of abscess infection in the peritonsillar area associated with a thrombophlebitis and caused by the strict anaerobic species Fusobacterium necrophorum. The thrombosis formed affects the internal jugular vein, from which the bacteria are seede...

journal_title：Expert review of anti-infective therapy

authors： Dahlén G,Ebenfelt A

更新日期：2011-02-01 00:00:00

abstract：:Linezolid is the first member of a new generation of antibiotics, the synthetic oxazolidinones, to become available, with a broad spectrum of in vitro activity against gram-positive organisms, including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecalis and vancomycin-resistant E. ...

journal_title：Expert review of anti-infective therapy

authors： Velissariou IM

更新日期：2006-12-01 00:00:00

abstract：:Introduction: Helicobacter Pylori (H.Pylori) is a pathogen that infects about 50% of the world's population and is known to be responsible for gastroduodenal diseases such as atrophic gastritis, peptic ulcer and stomach cancer. Nowadays, there is no treatment that ensures complete eradication. In addition, resistance ...

journal_title：Expert review of anti-infective therapy

authors： Safarov T,Kiran B,Bagirova M,Allahverdiyev AM,Abamor ES

更新日期：2019-10-01 00:00:00

abstract：:Ebola and Marburg viruses are emerging/re-emerging pathogens that pose a significant threat to human health. These naturally occurring viral infections frequently cause a lethal hemorrhagic fever in humans and nonhuman primates. The disastrous consequences of infection with these viruses have been pursued as potential...

journal_title：Expert review of anti-infective therapy

authors： Paragas J,Geisbert TW

更新日期：2006-02-01 00:00:00

abstract：:Infections due to multidrug-resistant pathogens have an increasing impact on patients undergoing cardiac surgery. Preoperative infections, such as endocarditis, and postoperative infections, including wound and device infection, influence patient outcomes. Special interest needs to be taken in patients admitted to car...

journal_title：Expert review of anti-infective therapy

authors： Kanzler I,Weis F,Beiras-Fernandez A

更新日期：2013-03-01 00:00:00

abstract：:Tinidazole has been used for bacterial vaginosis (BV) outside the USA for almost four decades. Tinidazole has recently been resurrected and FDA approved for trichomoniasis and BV in the USA and is being restudied as an alternative to metronidazole for BV. In vitro antimicrobial activity and pharmacokinetics studies in...

journal_title：Expert review of anti-infective therapy

authors： Nailor MD,Sobel JD

更新日期：2007-06-01 00:00:00

abstract：:Tuberculosis (TB) is mainly an intracellular infection of the lung alveolar macrophages, and any anti-TB agent must therefore be active at the macrophage. Among the available therapies, isoniazid and rifampicin are the most effective drugs against susceptible Mycobacterium tuberculosis, but they are ineffective agains...

journal_title：Expert review of anti-infective therapy

authors： Viveiros M,Martins M,Couto I,Rodrigues L,Machado D,Portugal I,Amaral L

更新日期：2010-04-01 00:00:00

abstract：:Management of anaerobic infections encompasses surgical procedures, antibacterial therapy and adjuncts. At present, metronidazole, penems, beta-lactam/beta-lactamase inhibitor combinations and chloramphenicol have the highest activity against obligate anaerobes. Tigecycline is a promising new agent. Other antibacteria...

journal_title：Expert review of anti-infective therapy

authors： Boyanova L,Kolarov R,Mitov I

更新日期：2007-08-01 00:00:00

abstract：INTRODUCTION:Onychomycosis is a chronic fungal infection of the nail bed, matrix or plate. It accounts for roughly 50% of all nail disease. As the prevalence of onychomycosis is increasing, a critical review of diagnostic techniques and treatment options is required. Areas covered: This review discusses the current dia...

journal_title：Expert review of anti-infective therapy

authors： Gupta AK,Mays RR,Versteeg SG,Shear NH,Piguet V

更新日期：2018-12-01 00:00:00

abstract：INTRODUCTION:International guidelines have recommended for many years to start antimicrobials as early as possible in sepsis and shock. This concept has been challenged by the controversial results of experimental studies and clinical cohorts and resulted in intense debate in the literature. This review aims to summari...

journal_title：Expert review of anti-infective therapy

authors： Dupuis C,Timsit JF

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Septic arthritis (SA) is an orthopedic emergency in childhood. It is uncommon in high resource settings. However, an incidence of 5-20 per 100,000 children has been reported in low-income countries. Area covered: The predictive value of serum markers is still under debate and the proposed diagnostic algori...

journal_title：Expert review of anti-infective therapy

authors： Chiappini E,Mastrolia MV,Galli L,De Martino M,Lazzeri S

更新日期：2016-11-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP) remains a major burden to the healthcare system and intubated patients in intensive care units. In fact, VAP is responsible for at least 50% of prescribed antibiotics to patients who need mechanical ventilation. One of the factors contributing to VAP pathogenesis is believed to be...

journal_title：Expert review of anti-infective therapy

authors： Loo CY,Lee WH,Young PM,Cavaliere R,Whitchurch CB,Rohanizadeh R

更新日期：2015-03-01 00:00:00