Abstract:
:Necrobacillosis, often used synonymously with Lemierre's syndrome, is a form of abscess infection in the peritonsillar area associated with a thrombophlebitis and caused by the strict anaerobic species Fusobacterium necrophorum. The thrombosis formed affects the internal jugular vein, from which the bacteria are seeded out in the bloodstream and cause bacteremia. Septicemia is a common complication with an often fatal outcome. Necrobacillosis is very rare and is referred to as the 'forgotten disease'. It is probably frequently overlooked in clinical practice in its early and milder forms such as tonsillitis (sore throat) and peritonsillar abscess. F. necrophorum frequently participates in these infections and is thus suspected to have an etiological role in Lemierre's syndrome. Similarly, F. necrophorum seems to play an important role in noma (cancrum oris) and this disease is also included in the necrobacillosis complex. Diagnosis of infections of the necrobacillosis complex seeks to disclose F. necrophorum in swab samples or blood culture. The most commonly used therapy is metronidazole in combination with penicillin or amoxicillin. Clindamycin is also an option, especially in cases of penicillin allergy.
journal_name
Expert Rev Anti Infect Therjournal_title
Expert review of anti-infective therapyauthors
Dahlén G,Ebenfelt Adoi
10.1586/eri.10.172subject
Has Abstractpub_date
2011-02-01 00:00:00pages
227-36issue
2eissn
1478-7210issn
1744-8336journal_volume
9pub_type
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,meta分析,评审
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journal_title:Expert review of anti-infective therapy
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journal_title:Expert review of anti-infective therapy
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journal_title:Expert review of anti-infective therapy
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,meta分析
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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更新日期:2011-06-01 00:00:00
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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更新日期:2011-12-01 00:00:00
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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更新日期:2014-12-01 00:00:00
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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更新日期:2013-07-01 00:00:00
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
doi:10.1586/14787210.2016.1135052
更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1586/14787210.2015.1023292
更新日期:2015-05-01 00:00:00
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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更新日期:2014-06-01 00:00:00
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00
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journal_title:Expert review of anti-infective therapy
pub_type: 评论,杂志文章
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journal_title:Expert review of anti-infective therapy
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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更新日期:2011-08-01 00:00:00
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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更新日期:2012-05-01 00:00:00
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章
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更新日期:2020-12-10 00:00:00
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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journal_title:Expert review of anti-infective therapy
pub_type: 杂志文章,评审
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journal_title:Expert review of anti-infective therapy
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更新日期:2010-06-01 00:00:00
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pub_type: 杂志文章,评审
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