Levofloxacin for the treatment of community-acquired pneumonia.

abstract：:Neurocysticercosis is a major cause of neurologic disease worldwide. In India and other developing countries, single small enhancing computed tomographic lesions representing solitary cysticercus granuloma are a common cause of new-onset seizures. The interesting feature of these solitary enhancing lesions is their sp...

journal_title：Expert review of anti-infective therapy

authors： Garg RK

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:Herpes zoster (HZ) or shingles occurs as a result of reactivation after a primary infection with varicella zoster virus (chickenpox). The burden of HZ in older adults in China is not well understood. We conducted a systematic literature review to understand the burden of disease related to HZ, its complica...

journal_title：Expert review of anti-infective therapy

authors： Yin D,Van Oorschot D,Jiang N,Marijam A,Saha D,Wu Z,Tang H,Diaz-Decaro J,Watson P,Xie X,Ren Y,He Y,Feng Y

更新日期：2020-09-30 00:00:00

abstract：:The management of anaerobic infection needs to be prompt and appropriate in order to ensure recovery. Management includes the use of hyperbaric oxygen, surgical methods and antimicrobial therapy. Various factors, such as efficacy, bacterial antimicrobial resistance, ability to reach appropriate antimicrobial levels at...

journal_title：Expert review of anti-infective therapy

authors： Brook I

更新日期：2004-02-01 00:00:00

abstract：:The 49th Annual Spring Meeting of the British Society of Parasitology was held at Nottingham University, UK, on 11-14 April 2011. Although a meeting of a national parasitological society, the meeting attracted approximately 375 delegates from 30 countries worldwide. Of the various themes at this meeting, two were focu...

journal_title：Expert review of anti-infective therapy

authors： Staines HM,Croft SL,Horrocks PD

更新日期：2011-07-01 00:00:00

abstract：:In 2013, an estimated 1.5 million HIV-positive pregnant women gave birth, with 240,000 children worldwide acquiring HIV. More than 90% of new pediatric infections occurred in Sub-Saharan Africa. The latest WHO guidelines recommended efavirenz (EFV)-based antiretroviral therapy as the first-line regimen for prevention ...

journal_title：Expert review of anti-infective therapy

authors： De Nardo P,Gentilotti E,Nguhuni B,Vairo F,Chaula Z,Nicastri E,Ippolito G

更新日期：2016-01-01 00:00:00

abstract：:Tuberculosis (TB) is mainly an intracellular infection of the lung alveolar macrophages, and any anti-TB agent must therefore be active at the macrophage. Among the available therapies, isoniazid and rifampicin are the most effective drugs against susceptible Mycobacterium tuberculosis, but they are ineffective agains...

journal_title：Expert review of anti-infective therapy

authors： Viveiros M,Martins M,Couto I,Rodrigues L,Machado D,Portugal I,Amaral L

更新日期：2010-04-01 00:00:00

abstract：:Having available tools to determine the prognosis of pediatric meningococcal sepsis at admission to the Intensive Care Unit or during the course of the disease constitutes a clinical necessity. Recently, new readily measurable circulating biomarkers have been described as an additional tool for severity classification...

journal_title：Expert review of anti-infective therapy

authors： Briassoulis G,Galani A

更新日期：2014-09-01 00:00:00

abstract：:Since the discovery of HIV 30 years ago, we have learned much about HIV in children and adolescents. Dramatic declines have occurred in mother-to-child transmission of HIV in resource-rich countries. Resource-poor countries struggle with improving prevention of mother-to-child transmission due to the lack of universal...

journal_title：Expert review of anti-infective therapy

authors： Anderson EJ,Yogev R

更新日期：2012-07-01 00:00:00

abstract：:Over the last few decades, various extended-spectrum β-lactamases (ESBLs), which are remotely related to the classical TEM and SHV families, have emerged. Among these, CTX-M, VEB and PER variants are of particular interest due to their widespread dissemination. This article will focus on these emerging ESBLs. CTX-M wa...

journal_title：Expert review of anti-infective therapy

authors： Akinci E,Vahaboglu H

更新日期：2010-11-01 00:00:00

abstract：:Lopinavir is a protease inhibitor (PI) for the treatment of HIV infection that was specifically designed to overcome the shortcomings of earlier agents in this class. It is the only PI coformulated with ritonavir, whose pharmacological boosting effect results in a highly potent, well-tolerated, clinically effective an...

journal_title：Expert review of anti-infective therapy

authors： Tan D,Walmsley S

更新日期：2007-02-01 00:00:00

abstract：:The aim of this article is to review the current literature examining the use of procalcitonin-guided antibiotic therapy for management of chronic obstructive pulmonary disease (COPD) exacerbations. Procalcitonin is a serum marker that rises in response to bacterial infections, but remains low in nonbacterial infectio...

journal_title：Expert review of anti-infective therapy

authors： Tokman S,Schuetz P,Bent S

更新日期：2011-06-01 00:00:00

abstract：:Introduction: Ceftobiprole is a fifth-generation cephalosporin with a broad spectrum of antimicrobial activity, including also methicillin-resistant Staphylococcus aureus (MRSA). Ceftobiprole is approved for the treatment of community-acquired pneumonia (CAP) and hospital-acquired pneumonia (HAP), excluding ventilator...

journal_title：Expert review of anti-infective therapy

authors： Giacobbe DR,De Rosa FG,Del Bono V,Grossi PA,Pea F,Petrosillo N,Rossolini GM,Tascini C,Tumbarello M,Viale P,Bassetti M

更新日期：2019-09-01 00:00:00

abstract：INTRODUCTION:Pneumocystis pneumonia is a potentially life-threatening pulmonary infection that occurs in immunocompromised individuals and HIV-infected patients with a low CD4 cell count. Trimethoprim-sulfamethoxazole has been used as the first-line agent for treatment, but mutations within dihydropteroate synthase gen...

journal_title：Expert review of anti-infective therapy

authors： Huang YS,Yang JJ,Lee NY,Chen GJ,Ko WC,Sun HY,Hung CC

更新日期：2017-09-01 00:00:00

abstract：:Antifungal susceptibility testing should identify in vitro resistance among a normally susceptible population or should detect the development of resistance during therapy. The Clinical and Laboratory Standards Institute (CLSI; formerly the National Committee for Clinical Laboratory Standards [NCCLS]) has developed re...

journal_title：Expert review of anti-infective therapy

authors： Cantón E,Espinel-Ingroff A,Pemán J

更新日期：2009-02-01 00:00:00

abstract：:Intracellular pathogens present a major health risk because of their innate ability to evade clearance. Their location within host cells and ability to react to the host environment by mutation or transcriptional changes often enables survival mechanisms to resist standard therapies. Host-directed drugs do not target ...

journal_title：Expert review of anti-infective therapy

authors： Collier MA,Gallovic MD,Peine KJ,Duong AD,Bachelder EM,Gunn JS,Schlesinger LS,Ainslie KM

更新日期：2013-11-01 00:00:00

abstract：:Tuberculosis continues to be a major global health problem. Lack of accurate, rapid and cost-effective diagnostic tests poses a huge obstacle to global TB control. While several new diagnostic tools are being developed and evaluated for TB, it is important that new tools are introduced for widespread use only after ca...

journal_title：Expert review of anti-infective therapy

authors： Sohn H,Minion J,Albert H,Dheda K,Pai M

更新日期：2009-08-01 00:00:00

abstract：:Human enteritis resulting from the consumption of poultry products contaminated with serovars of Salmonella enterica remains a major public-health concern. Reducing food contamination by preventing or controlling infection in the chicken during rearing is an attractive solution. An accurate understanding of the mechan...

journal_title：Expert review of anti-infective therapy

authors： Beal RK,Smith AL

更新日期：2007-10-01 00:00:00

abstract：:As a consequence of antibiotic overuse and misuse, nosocomial infections caused by multidrug-resistant bacteria represent a physician's nightmare throughout the world. No newer antimicrobials active against Pseudomonas aeruginosa, the main multidrug-resistant nosocomial pathogen, are available or under investigation. ...

journal_title：Expert review of anti-infective therapy

authors： Giamarellou H

更新日期：2006-08-01 00:00:00

abstract：:Rodent-borne hantaviruses (family Bunyaviridae, genus Hantavirus) cause hantavirus pulmonary syndrome in the Americas and hemorrhagic fever with renal syndrome in Europe and Asia. The viruses are transmitted to humans mainly by inhalation of virus-contaminated aerosols of rodent excreta and secreta. Classic clinical h...

journal_title：Expert review of anti-infective therapy

authors： Mattar S,Guzmán C,Figueiredo LT

更新日期：2015-08-01 00:00:00

abstract：INTRODUCTION:We assessed the knowledge of, attitude toward antimicrobial resistance (AMR) and practice of antimicrobial stewardship (AMS) among physicians in Nigeria to provide future guidance to the Nigerian National Action Plan for AMR. METHODS:A descriptive cross-sectional questionnaire-based study explored the phy...

journal_title：Expert review of anti-infective therapy

authors： Babatola AO,Fadare JO,Olatunya OS,Obiako R,Enwere O,Kalungia A,Ojo TO,Sunmonu TA,Desalu O,Godman B

更新日期：2020-11-02 00:00:00

abstract：:Introduction: Helicobacter Pylori (H.Pylori) is a pathogen that infects about 50% of the world's population and is known to be responsible for gastroduodenal diseases such as atrophic gastritis, peptic ulcer and stomach cancer. Nowadays, there is no treatment that ensures complete eradication. In addition, resistance ...

journal_title：Expert review of anti-infective therapy

authors： Safarov T,Kiran B,Bagirova M,Allahverdiyev AM,Abamor ES

更新日期：2019-10-01 00:00:00

abstract：:Despite significant advances in the day-to-day management of patients receiving hematopoietic stem cell transplantations, including the introduction of new antiviral drugs, cytomegalovirus (CMV) infection continues to be a major cause of morbidity and mortality. The aim of this article is to undertake a literature-bas...

journal_title：Expert review of anti-infective therapy

authors： Bacigalupo A,Boyd A,Slipper J,Curtis J,Clissold S

更新日期：2012-11-01 00:00:00

abstract：:Endobronchial tuberculosis is defined as tuberculous infection of the tracheobronchial tree. Although clinical features differ between various types and stages of endobronchial tuberculosis, common symptoms are cough, hemoptysis, sputum production, wheezing, chest pain, fever and dyspnea. Endobronchial tuberculosis is...

journal_title：Expert review of anti-infective therapy

authors： Rikimaru T

更新日期：2004-04-01 00:00:00

abstract：:Although penicillin remains the first-choice treatment for Streptococcus pyogenes infection, macrolides are important alternatives for allergic patients and lincosamides are recommended together with β-lactams in invasive infections. S. pyogenes may exhibit macrolide resistance because of active efflux (mef genes) or ...

journal_title：Expert review of anti-infective therapy

authors： Silva-Costa C,Friães A,Ramirez M,Melo-Cristino J

更新日期：2015-05-01 00:00:00

abstract：:Hospital infection due to multidrug-resistant Gram-positive bacteria may often represent a life-threatening challenge; thus, to appropriately combat them, clinicians should be confident and systematically apply several important pharmacodynamic concepts. The concept of 'correct antibiotic treatment' should include, in...

journal_title：Expert review of anti-infective therapy

authors： Pea F,Viale P

更新日期：2007-04-01 00:00:00

abstract：INTRODUCTION:COVID-19 disease progresses through a number of distinct phases. The management of each phase is unique and specific. The pulmonary phase of COVID-19 is characterized by an organizing pneumonia with profound immune dysregulation, activation of clotting, and a severe microvascular injury culminating in seve...

journal_title：Expert review of anti-infective therapy

authors： Marik PE,Kory P,Varon J,Iglesias J,Meduri GU

更新日期：2020-08-18 00:00:00

abstract：:Tinidazole has been used for bacterial vaginosis (BV) outside the USA for almost four decades. Tinidazole has recently been resurrected and FDA approved for trichomoniasis and BV in the USA and is being restudied as an alternative to metronidazole for BV. In vitro antimicrobial activity and pharmacokinetics studies in...

journal_title：Expert review of anti-infective therapy

authors： Nailor MD,Sobel JD

更新日期：2007-06-01 00:00:00

abstract：:Ceftobiprole is among the first of a new generation of cephalosporins with activity against aerobic Gram-negative bacilli, which extends to cefepime-sensitive Pseudomonas aeruginosa, and activity against Gram-positive organisms, which includes methicillin-resistant Staphylococcus aureus. Ceftobiprole is currently unde...

journal_title：Expert review of anti-infective therapy

authors： Schirmer PL,Deresinski SC

更新日期：2009-09-01 00:00:00

abstract：INTRODUCTION:Listeriosis is an uncommon foodborne infection that may cause moderate maternal illness, but can be extremely serious for the fetus and the newborn. Several guidelines have been elaborated in order to help clinicians on the care of pregnant women with known or suspected exposure to Listeria monocytogenes. ...

journal_title：Expert review of anti-infective therapy

authors： Pucci L,Massacesi M,Liuzzi G

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:The management of latent tuberculosis (LTBI) in children represents an important issue for paediatricians because of the disease burden, the lack of a gold standard for the diagnosis and the high annual risk of progression to active disease. Areas covered: A review of English language articles on LTBI in c...

journal_title：Expert review of anti-infective therapy

authors： Venturini E,Tersigni C,Chiappini E,de Martino M,Galli L

更新日期：2017-04-01 00:00:00