Ceftobiprole: drug evaluation and place in therapy.

abstract：:Neurocysticercosis is the most common parasitic disease of the CNS. Intracranial neurocysticercosis is classified into cerebral parenchymal and extraparenchymal forms (subarachnoidal and intraventricular). Current medical therapy for parenchymal and extraparenchymal neurocysticercosis invovles the use of anticysticerc...

journal_title：Expert review of anti-infective therapy

authors： Garg RK

更新日期：2008-08-01 00:00:00

abstract：:Lymphogranuloma venereum (LGV) is a sexually transmitted infection, previously only seen in tropical regions. This changed in 2003 when the first endemically acquired LGV cases were reported in Rotterdam, the Netherlands, among predominantly HIV positive men who have sex with men (MSM). Early diagnosis is important to...

journal_title：Expert review of anti-infective therapy

authors： de Vrieze NH,de Vries HJ

更新日期：2014-06-01 00:00:00

abstract：:Coinfection with hepatitis C in HIV-infected patients has been reported in 15-70% of patients depending on the mode of acquisition of both viruses. As recent advances in HIV-directed antiviral therapy have markedly delayed HIV progression and mortality, the incidence of complications arising from hepatitis C-associate...

journal_title：Expert review of anti-infective therapy

authors： Vyas JJ,Brown RS,Gaglio PJ

更新日期：2003-10-01 00:00:00

abstract：:Invasive aspergillosis (IA) is currently an important cause of morbidity and mortality in hematopoietic stem cell transplant and solid organ transplant recipients. A high index of suspicion and careful clinical and radiological examinations are the keys to identifying infected patients early. Chest computerized axial ...

journal_title：Expert review of anti-infective therapy

authors： Salman N,Törün SH,Budan B,Somer A

更新日期：2011-03-01 00:00:00

abstract：:Lopinavir is a protease inhibitor (PI) for the treatment of HIV infection that was specifically designed to overcome the shortcomings of earlier agents in this class. It is the only PI coformulated with ritonavir, whose pharmacological boosting effect results in a highly potent, well-tolerated, clinically effective an...

journal_title：Expert review of anti-infective therapy

authors： Tan D,Walmsley S

更新日期：2007-02-01 00:00:00

abstract：INTRODUCTION:The advent, more than two decades ago, of monoclonal antibodies and soluble receptors targeting tumor necrosis factor (TNF)-α has revolutionized the therapeutic approach to otherwise difficult-to-treat autoimmune and inflammatory diseases. However, due to the pleiotropic functions played by this pro-inflam...

journal_title：Expert review of anti-infective therapy

authors： Fernández-Ruiz M,Aguado JM

更新日期：2018-12-01 00:00:00

abstract：:Use of nonsystemic antimicrobials with activity against enteropathogens is a promising approach for treatment of infectious diarrhea and other nonsystemic gastrointestinal infections. Rifaximin is approved by the US FDA for the treatment of travelers' diarrhea caused by noninvasive strains of Escherichia coli in patie...

journal_title：Expert review of anti-infective therapy

authors： Cottreau J,Baker SF,DuPont HL,Garey KW

更新日期：2010-07-01 00:00:00

abstract：:Multidrug chemotherapy for 6-9-months is one of the primary treatments in effective control of tuberculosis, although the mechanisms underlying the persistence of its etiological agent, Mycobacterium tuberculosis, against antibiotics remain unclear. Ever-mounting evidence indicates that the survival of many environmen...

journal_title：Expert review of anti-infective therapy

authors： Islam MS,Richards JP,Ojha AK

更新日期：2012-09-01 00:00:00

abstract：:Although penicillin remains the first-choice treatment for Streptococcus pyogenes infection, macrolides are important alternatives for allergic patients and lincosamides are recommended together with β-lactams in invasive infections. S. pyogenes may exhibit macrolide resistance because of active efflux (mef genes) or ...

journal_title：Expert review of anti-infective therapy

authors： Silva-Costa C,Friães A,Ramirez M,Melo-Cristino J

更新日期：2015-05-01 00:00:00

abstract：INTRODUCTION:COVID-19 disease progresses through a number of distinct phases. The management of each phase is unique and specific. The pulmonary phase of COVID-19 is characterized by an organizing pneumonia with profound immune dysregulation, activation of clotting, and a severe microvascular injury culminating in seve...

journal_title：Expert review of anti-infective therapy

authors： Marik PE,Kory P,Varon J,Iglesias J,Meduri GU

更新日期：2020-08-18 00:00:00

abstract：:The 49th Annual Spring Meeting of the British Society of Parasitology was held at Nottingham University, UK, on 11-14 April 2011. Although a meeting of a national parasitological society, the meeting attracted approximately 375 delegates from 30 countries worldwide. Of the various themes at this meeting, two were focu...

journal_title：Expert review of anti-infective therapy

authors： Staines HM,Croft SL,Horrocks PD

更新日期：2011-07-01 00:00:00

abstract：:Human rickettsioses caused by intracellular bacteria of the genus Rickettsia are distributed worldwide and are transmitted by arthropod vectors such as ticks, fleas, mites and lice. They have a wide range of manifestations from benign to life-threatening diseases. Mortality rates of up to 30% have been reported for so...

journal_title：Expert review of anti-infective therapy

authors： Botelho-Nevers E,Socolovschi C,Raoult D,Parola P

更新日期：2012-12-01 00:00:00

abstract：:Mycobacterium caprae, a member of the Mycobacterium tuberculosis complex, causes tuberculosis (TB) in man and animals. Some features distinguish M. caprae from its epidemiological twin, Mycobacterium bovis: M. caprae is evolutionarily older, accounts for a smaller burden of zoonotic TB and is not globally distributed,...

journal_title：Expert review of anti-infective therapy

authors： Prodinger WM,Indra A,Koksalan OK,Kilicaslan Z,Richter E

更新日期：2014-12-01 00:00:00

abstract：:Influenza has circulated among humans for centuries and kills more people than many newly emerging diseases. The present methods for control of influenza are not adequate, especially for dealing with a pandemic. In the face of a rapidly spreading outbreak, a race to isolate the virus and prepare a vaccine would probab...

journal_title：Expert review of anti-infective therapy

authors： Epstein SL

更新日期：2003-12-01 00:00:00

abstract：:Fluoroquinolones are an important group of antibiotics that are used widely in the treatment of various infectious diseases in adults as a result of their excellent spectrum of activity, significant tissue penetration and convenient routes of administration. Their use in children, however, has been limited until recen...

journal_title：Expert review of anti-infective therapy

authors： Velissariou IM

更新日期：2006-10-01 00:00:00

abstract：:Sertaconazole is an imidazole-type antifungal agent that has shown considerable in vitro activity against pathogenic fungi. Various studies carried out in animal models, clinical and toxicologic trials have confirmed the value of sertaconazole in the topical treatment of superficial mycoses in dermatology and gynecolo...

journal_title：Expert review of anti-infective therapy

authors： Carrillo-Muñoz AJ,Giusiano G,Ezkurra PA,Quindós G

更新日期：2005-06-01 00:00:00

abstract：:The 6th World Congress of the World Society for Pediatric Infectious Diseases (WSPID), which was recently held in Buenos Aires, Argentina, between 18 and 22 November 2009, attracted 2401 attendees from 90 countries representing six continents. The WSPID, founded in 1994 by Professor Saldana Gonzalez of the Mexican Ped...

journal_title：Expert review of anti-infective therapy

authors： Falade AG

更新日期：2010-03-01 00:00:00

abstract：:Since the discovery of HIV 30 years ago, we have learned much about HIV in children and adolescents. Dramatic declines have occurred in mother-to-child transmission of HIV in resource-rich countries. Resource-poor countries struggle with improving prevention of mother-to-child transmission due to the lack of universal...

journal_title：Expert review of anti-infective therapy

authors： Anderson EJ,Yogev R

更新日期：2012-07-01 00:00:00

abstract：:Hepatitis C virus infection is the leading cause of chronic liver disease in the western world. Chronic liver diseases may cause, through portal hypertension, the development of gastroesophageal varices, which can then bleed. We assess the findings of a study aimed at identifying the incidence of de novo varix develop...

journal_title：Expert review of anti-infective therapy

authors： Gentile I,Borgia G

更新日期：2010-08-01 00:00:00

abstract：:HBV infection remains a major global health problem and continues to be a common cause of liver-related morbidity and mortality in both immunocompetent and immunosuppressed individuals. Reactivation of HBV is a serious complication of chemotherapy/immunosuppressive therapy in patients with HBV infection. In this artic...

journal_title：Expert review of anti-infective therapy

authors： Idilman R,Arat M

更新日期：2011-08-01 00:00:00

abstract：:Chronic hepatitis B is a worldwide health problem. Research interests have focused on the development of potent and safe antiviral agents with low resistance rates. Among these, telbivudine is an oral nucleoside analogue with specific activity against hepatitis B virus DNA polymerase. Various prospective, randomized c...

journal_title：Expert review of anti-infective therapy

authors： Lui YY,Chan HL

更新日期：2009-04-01 00:00:00

abstract：:The acyclic nucleoside phosphonates [HPMPC: cidofovir, Vistide; PMEA: adefovir dipivoxil, Hepsera; and PMPA: tenofovir, Viread] have proven to be effective in vitro (cell culture systems) and in vivo (animal models and clinical studies) against a wide variety of DNA virus and retrovirus infections, for example, cidofo...

journal_title：Expert review of anti-infective therapy

authors： De Clercq E

更新日期：2003-06-01 00:00:00

abstract：:Antibiotic resistance is an important factor influencing clinical outcome for patients in intensive care units. It is also associated with increased healthcare costs resulting from prolonged patient stays. The problem of antibiotic resistance is particularly acute in intensive care units because they house seriously i...

journal_title：Expert review of anti-infective therapy

authors： Johnson AP

更新日期：2003-08-01 00:00:00

abstract：:As the result of improved bacteriological techniques, Kingella kingae is emerging as an important cause of infections of the skeletal system in children younger than 2 years of age. This review details the bacteriological features and detection methods of this pathogen, as well as the epidemiology, clinical presentati...

journal_title：Expert review of anti-infective therapy

authors： Yagupsky P

更新日期：2004-10-01 00:00:00

abstract：:Invasive candidiasis, including candidemia (IC/C), is a major cause of morbidity and mortality among hospitalized patients. While incidence is higher in intensive care units, the majority of cases of candidemia are documented in medical wards. Although Candida albicans is still the most frequently isolated species, IC...

journal_title：Expert review of anti-infective therapy

authors： Tagliaferri E,Menichetti F

更新日期：2015-06-01 00:00:00

abstract：:HIV-associated nephropathy (HIVAN) is the most well-known and aggressive kidney disease in HIV-1-infected patients. A variant of focal segmental glomerulosclerosis, it is characterized by the collapse of the glomerular tuft with podocyte hypertrophy/hyperplasia and foot process effacement, often with concurrent tubula...

journal_title：Expert review of anti-infective therapy

authors： Atta MG,Lucas GM,Fine DM

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The introduction of antibiotics into modern medicine has changed clinical care by saving millions of lives. However, misuse of antibiotics has led to their benefits being overshadowed by the development of antimicrobial resistance. AIMS OF STUDY:This study aimed to assess university students' knowledge and ...

journal_title：Expert review of anti-infective therapy

authors： Haque M,Rahman NAA,McKimm J,Binti Abdullah SL,Islam MZ,Zulkifli Z,Saidin NB,Azhar NIK,Binti Lutfi SNN,Binti Othman NSA

更新日期：2019-04-01 00:00:00

abstract：:Intracellular pathogens present a major health risk because of their innate ability to evade clearance. Their location within host cells and ability to react to the host environment by mutation or transcriptional changes often enables survival mechanisms to resist standard therapies. Host-directed drugs do not target ...

journal_title：Expert review of anti-infective therapy

authors： Collier MA,Gallovic MD,Peine KJ,Duong AD,Bachelder EM,Gunn JS,Schlesinger LS,Ainslie KM

更新日期：2013-11-01 00:00:00

abstract：:Diarrhea is the second largest cause of mortality worldwide in children from the perinatal period to the age of 5 years. Rotavirus has been the most commonly identified viral cause of diarrhea in children. Norovirus is now recognized as the second most common viral pathogen. Adenovirus, astrovirus and sapovirus are th...

journal_title：Expert review of anti-infective therapy

authors： Anderson EJ

更新日期：2010-02-01 00:00:00

abstract：:Evaluation of: Riedel S, Melendez JH, An AT, Rosenbaum JE, Zenilman JM. Procalcitonin as a marker for the detection of bacteremia and sepsis in the emergency department. Am. J. Clin. Pathol. 135(2), 182-189 (2011). In a recent report, Riedel et al. proposed a procalcitonin cutoff of 0.1 ng/ml to rule out bacteremia in...

journal_title：Expert review of anti-infective therapy

authors： Albrich WC,Mueller B

更新日期：2011-06-01 00:00:00