Mycobacterium caprae infection in humans.

abstract：:Treatment of second-stage gambiense human African trypanosomiasis relied on toxic arsenic-based derivatives for over 50 years. The availability and subsequent use of eflornithine, initially in monotherapy and more recently in combination with nifurtimox (NECT), has drastically improved the prognosis of treated patient...

journal_title：Expert review of anti-infective therapy

authors： Eperon G,Balasegaram M,Potet J,Mowbray C,Valverde O,Chappuis F

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Neuraminidase inhibitors (NAIs) reduce influenza symptoms but clear evidence of relationships between viral titer reduction and symptom alleviation is lacking. This open-label, randomized study evaluated differences in viral dynamics between NAIs, and relationships between viral dynamics and influenza sympto...

journal_title：Expert review of anti-infective therapy

authors： Hirotsu N,Saisho Y,Hasegawa T,Shishido T

更新日期：2018-02-01 00:00:00

abstract：:Reversing the spread of HIV infection and the incidence of malaria constitute two of the Millenium Development Goals. However, despite recent achievements, both diseases still entail global heath problems. Furthermore, their overlapping geographical distribution raises concerns and challenges for potential immunologic...

journal_title：Expert review of anti-infective therapy

authors： González R,Ataíde R,Naniche D,Menéndez C,Mayor A

更新日期：2012-02-01 00:00:00

abstract：INTRODUCTION:In December 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak occurred and caused the coronavirus disease of 2019 (COVID-19), which affected ~ 190 countries. The World Health Organization (WHO) has declared COVID-19 a pandemic on 11 March 2020. AREA COVERED:In the review, a com...

journal_title：Expert review of anti-infective therapy

authors： Bhagat S,Yadav N,Shah J,Dave H,Swaraj S,Tripathi S,Singh S

更新日期：2020-12-07 00:00:00

abstract：:Antibiotic resistance is an important factor influencing clinical outcome for patients in intensive care units. It is also associated with increased healthcare costs resulting from prolonged patient stays. The problem of antibiotic resistance is particularly acute in intensive care units because they house seriously i...

journal_title：Expert review of anti-infective therapy

authors： Johnson AP

更新日期：2003-08-01 00:00:00

abstract：:The management of anaerobic infection needs to be prompt and appropriate in order to ensure recovery. Management includes the use of hyperbaric oxygen, surgical methods and antimicrobial therapy. Various factors, such as efficacy, bacterial antimicrobial resistance, ability to reach appropriate antimicrobial levels at...

journal_title：Expert review of anti-infective therapy

authors： Brook I

更新日期：2004-02-01 00:00:00

abstract：:The authors sought to study whether extended or continuous infusion of cephalosporins is associated with better clinical outcomes than short-term infusion. PubMed and Scopus databases were systematically searched. Studies reporting the clinical outcomes of patients receiving extended or continuous infusion (≥3 or 24 h...

journal_title：Expert review of anti-infective therapy

authors： Korbila IP,Tansarli GS,Karageorgopoulos DE,Vardakas KZ,Falagas ME

更新日期：2013-06-01 00:00:00

abstract：:Bacteremias represent severe infectious complications following hematopoietic stem cell transplantation (HSCT). Frequency is highest during the pre-engraftment period, both in autologous and in allogeneic HSCT, when patients are granulocytopenic. In the postengraftment period, bacteremias are also frequent in the abse...

journal_title：Expert review of anti-infective therapy

authors： Castagnola E,Faraci M

更新日期：2009-06-01 00:00:00

abstract：:Neurocysticercosis is a major cause of neurologic disease worldwide. In India and other developing countries, single small enhancing computed tomographic lesions representing solitary cysticercus granuloma are a common cause of new-onset seizures. The interesting feature of these solitary enhancing lesions is their sp...

journal_title：Expert review of anti-infective therapy

authors： Garg RK

更新日期：2008-02-01 00:00:00

abstract：:The constant new emergence of life-threatening human respiratory viral pathogens presents new challenges to clinicians who are left with no available therapeutic interventions. Highly pathogenic strains of influenza A virus (IAV) share an enhanced capacity to propagate to the lower airways and paralyze alveolar macrop...

journal_title：Expert review of anti-infective therapy

authors： Coulombe F,Divangahi M

更新日期：2014-11-01 00:00:00

abstract：:Neurocysticercosis is the most common cause of late-onset epilepsy in developing countries. The larval stage of Taenia solium is the causative agent of the disease. Recent advances in neuroimaging and serologic diagnostic techniques have led to increased recognition of its importance, but its pathogenesis is just begi...

journal_title：Expert review of anti-infective therapy

authors： Serpa JA,Yancey LS,White AC Jr

更新日期：2006-12-01 00:00:00

abstract：:Hepatitis E, caused by hepatitis E virus, is a disease of global significance, causing 20 million infections each year. Genotypes 1 and 2 have vastly different epidemiological patterns from genotypes 3 and 4. In genotype 1 and 2 endemic areas, most infections and illness occur in persons 15-30 years of age, with pregn...

journal_title：Expert review of anti-infective therapy

authors： Kmush BL,Nelson KE,Labrique AB

更新日期：2015-01-01 00:00:00

abstract：:The acyclic nucleoside phosphonates [HPMPC: cidofovir, Vistide; PMEA: adefovir dipivoxil, Hepsera; and PMPA: tenofovir, Viread] have proven to be effective in vitro (cell culture systems) and in vivo (animal models and clinical studies) against a wide variety of DNA virus and retrovirus infections, for example, cidofo...

journal_title：Expert review of anti-infective therapy

authors： De Clercq E

更新日期：2003-06-01 00:00:00

abstract：:Human enteritis resulting from the consumption of poultry products contaminated with serovars of Salmonella enterica remains a major public-health concern. Reducing food contamination by preventing or controlling infection in the chicken during rearing is an attractive solution. An accurate understanding of the mechan...

journal_title：Expert review of anti-infective therapy

authors： Beal RK,Smith AL

更新日期：2007-10-01 00:00:00

abstract：:Ceftobiprole is among the first of a new generation of cephalosporins with activity against aerobic Gram-negative bacilli, which extends to cefepime-sensitive Pseudomonas aeruginosa, and activity against Gram-positive organisms, which includes methicillin-resistant Staphylococcus aureus. Ceftobiprole is currently unde...

journal_title：Expert review of anti-infective therapy

authors： Schirmer PL,Deresinski SC

更新日期：2009-09-01 00:00:00

abstract：INTRODUCTION:Drug-resistant tuberculous meningitis has been reported worldwide. Isoniazid mono-resistance is the most frequent cause of drug-resistant tuberculous meningitis, a life-threatening disease. Extensive drug-resistant tuberculous meningitis has also been reported in some isolated case reports. Areas covered: ...

journal_title：Expert review of anti-infective therapy

authors： Garg RK,Rizvi I,Malhotra HS,Uniyal R,Kumar N

更新日期：2018-11-01 00:00:00

abstract：:The prodrug isavuconazonium sulfate (BAL8557) is an extended-spectrum water-soluble triazole, developed for the treatment of severe invasive and life-threatening fungal diseases. Its active moiety, BAL4815, is a potent inhibitor of ergosterol biosynthesis, resulting in the disruption of fungal membrane structure and f...

journal_title：Expert review of anti-infective therapy

authors： Seyedmousavi S,Verweij PE,Mouton JW

更新日期：2015-01-01 00:00:00

abstract：:A defective mucociliary clearance facilitates colonization with bacteria and fungal spores in cystic fibrosis patients. Yeasts and molds are cultured from the cystic fibrosis respiratory tract and often their clinical relevance is unknown. Candida spp. are the most commonly isolated yeasts, whereas Aspergillus spp., S...

journal_title：Expert review of anti-infective therapy

authors： Müller FM,Seidler M

更新日期：2010-08-01 00:00:00

abstract：:Since the advent of combined antiretroviral therapy there have been reductions in mortality and morbidity from HIV, transforming the disease into a chronic medical condition where newly diagnosed individuals can expect to live a near-normal life expectancy. When choosing therapy, probably the most important considerat...

journal_title：Expert review of anti-infective therapy

authors： Scourfield A,Waters L,Nelson M

更新日期：2011-11-01 00:00:00

abstract：:In clinical practice, a significant proportion of HIV-infected patients receive lopinavir/ritonavir (LPV/r) as a component of highly active antiretroviral therapy (HAART). The study by Israr et al. was designed to evaluate the effects of the HIV protease inhibitor LPV/r on gingival epithelium growth and differentiatio...

journal_title：Expert review of anti-infective therapy

authors： Rivero A,Pérez-Camacho I

更新日期：2010-12-01 00:00:00

abstract：:Sertaconazole is an imidazole-type antifungal agent that has shown considerable in vitro activity against pathogenic fungi. Various studies carried out in animal models, clinical and toxicologic trials have confirmed the value of sertaconazole in the topical treatment of superficial mycoses in dermatology and gynecolo...

journal_title：Expert review of anti-infective therapy

authors： Carrillo-Muñoz AJ,Giusiano G,Ezkurra PA,Quindós G

更新日期：2005-06-01 00:00:00

abstract：INTRODUCTION:Invasive fungal diseases (IFDs) have received attention as an emerging public health threat, are difficult to diagnose and to treat, and are associated with substantial morbidity and mortality. The standard of care in IFD management requires an early and targeted antifungal treatment, hence covers - amongs...

journal_title：Expert review of anti-infective therapy

authors： Knabl L,Lass-Flörl C

更新日期：2020-08-01 00:00:00

abstract：:Although penicillin remains the first-choice treatment for Streptococcus pyogenes infection, macrolides are important alternatives for allergic patients and lincosamides are recommended together with β-lactams in invasive infections. S. pyogenes may exhibit macrolide resistance because of active efflux (mef genes) or ...

journal_title：Expert review of anti-infective therapy

authors： Silva-Costa C,Friães A,Ramirez M,Melo-Cristino J

更新日期：2015-05-01 00:00:00

abstract：:As a consequence of antibiotic overuse and misuse, nosocomial infections caused by multidrug-resistant bacteria represent a physician's nightmare throughout the world. No newer antimicrobials active against Pseudomonas aeruginosa, the main multidrug-resistant nosocomial pathogen, are available or under investigation. ...

journal_title：Expert review of anti-infective therapy

authors： Giamarellou H

更新日期：2006-08-01 00:00:00

abstract：:This report, completed in November 2003, is intended to serve as a resource for physicians, public health officials and organizations involved in the evaluation and treatment of Lyme disease. ...

journal_title：Expert review of anti-infective therapy

authors： Cameron D,Gaito A,Harris N,Bach G,Bellovin S,Bock K,Bock S,Burrascano J,Dickey C,Horowitz R,Phillips S,Meer-Scherrer L,Raxlen B,Sherr V,Smith H,Smith P,Stricker R,ILADS Working Group.

更新日期：2004-01-01 00:00:00

abstract：:Botulism is a severe neuroparalytic disease resulting from exposure to one of the most poisonous toxins to humans. Because of this high potency and the use of toxins as biological weapons, botulism is a public health concern and each case represents an emergency. Current therapy involves respiratory supportive care an...

journal_title：Expert review of anti-infective therapy

authors： Anniballi F,Lonati D,Fiore A,Auricchio B,De Medici D,Locatelli CA

更新日期：2014-09-01 00:00:00

abstract：:Chronic hepatitis C is a major worldwide health problem with an estimated prevalence of 1.6-2%. The prognosis of chronic hepatitis C depends on the rate of fibrosis progression which, over a 20-30-year time span, may determine the risk of developing cirrhosis and its complications, namely hepatocellular carcinoma, liv...

journal_title：Expert review of anti-infective therapy

authors： Aghemo A,Rumi MG,Colombo M

更新日期：2009-10-01 00:00:00

abstract：INTRODUCTION:The nervous system is involved in 10-15% of patients infected with B. burgdorferi, B. afzelii and B. garinii. This review will address widespread misconceptions about the clinical phenomenology, diagnostic approach and response to treatment of neuroborreliosis. Areas covered: Improvements in diagnostic tes...

journal_title：Expert review of anti-infective therapy

authors： Halperin JJ

更新日期：2018-01-01 00:00:00

abstract：:Malaria is a curable disease, provided timely access to efficacious drugs is sought. Poor quality and, in particular, falsified antimalarial drugs harm the population of malaria endemic areas; they put lives in peril, cause economic losses to patients, families, industry, and generally undermine the trust in health sy...

journal_title：Expert review of anti-infective therapy

authors： Chaccour C,Kaur H,Del Pozo JL

更新日期：2015-04-01 00:00:00

abstract：:Despite increased malaria control efforts, recent reports indicate that over 1.2 million deaths due to malaria occurred in 2010. Pregnant women represent a particularly vulnerable risk group as malaria infection can lead to life-threatening disease for the mother and fetus. With 125 million women at risk of malaria in...

journal_title：Expert review of anti-infective therapy

authors： Conroy AL,McDonald CR,Kain KC

更新日期：2012-11-01 00:00:00